beta-Carboline alkaloids from the leaves of Trigonostemon lii YT Chang
Li, Shi-Fei1,2; Zhang, Yu1; Li, Yan1; Li, Xin-Rao1,2; Kong, Ling-Mei1; Tan, Cheng-Jian1; Li, Shun-Lin1; Di, Ying-Tong1; He, Hong-Ping1; Hao, Xiao-Jiang1
Corresponding AuthorDi, YT (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China, diyt@mail.kib.ac.cn ; hehongping@mail.kib.ac.cn
2012-03-15
Source PublicationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN0960-894X
Volume22Issue:6Pages:2296-2299
AbstractA phytochemical work on the alkaloid constituents from Trigonostemon lii Y.T. Chang was conducted to give six new beta-carboline alkaloids, trigonostemines A-F (1-6) and eight known beta-carboline alkaloids (7-14). Their structures were elucidated by extensive spectroscopic techniques including 2D NMR experiments and mass spectrometry. All of the compounds were evaluated for their cytotoxic activities against the HL-60, SMMC-7721, A-549, MCF-7, and SW480 human cancer cell lines. Trigonostemines A and B (1 and 2) exhibited stronger inhibitory activities than the positive control (cisplatin) in some cell lines. (C) 2012 Elsevier Ltd. All rights reserved.
KeywordTrigonostemon Lii Beta-carboline Alkaloids Trigonostemines A-f Cytotoxic Activity
Subject AreaChemistry, Medicinal ; Chemistry, Organic
DOI10.1016/j.bmcl.2012.01.106
Indexed BySCI
Language英语
WOS Research AreaPharmacology & Pharmacy ; Chemistry
WOS SubjectChemistry, Medicinal ; Chemistry, Organic
WOS IDWOS:000301285500034
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/10391
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Li, Shi-Fei,Zhang, Yu,Li, Yan,et al. beta-Carboline alkaloids from the leaves of Trigonostemon lii YT Chang[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2012,22(6):2296-2299.
APA Li, Shi-Fei.,Zhang, Yu.,Li, Yan.,Li, Xin-Rao.,Kong, Ling-Mei.,...&Hao, Xiao-Jiang.(2012).beta-Carboline alkaloids from the leaves of Trigonostemon lii YT Chang.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,22(6),2296-2299.
MLA Li, Shi-Fei,et al."beta-Carboline alkaloids from the leaves of Trigonostemon lii YT Chang".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 22.6(2012):2296-2299.
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