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Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60
作者:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying;  Liu, Xingyong;  Siddique, Abu Nasar;  Zhang, Li;  Zuo, Zhili
收藏  |  浏览/下载：146/0  |  提交时间：2018/11/12
Checkpoint kinase 1 inhibitor  Virtual screening  Pharmacophore modeling  Molecular docking  Molecular dynamics simulations  
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
作者:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
收藏  |  浏览/下载：371/0  |  提交时间：2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization  
12th全国天然有机化学学术会议摘要集 会议录
会议录编者:  中国化学会
Adobe PDF(123481Kb)  |  收藏  |  浏览/下载：181/8  |  提交时间：2018/10/24
Structural Elucidation and Biomimetic Synthesis of (+/-)-Cochlactone A with Anti-Inflammatory Activity 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 10, 页码: 5516-5522
作者:  Peng, Xing-Rong;  Lu, Shuang-Yang;  Shao, Li-Dong;  Zhou, Lin;  Qiu, Ming-Hua
浏览  |  Adobe PDF(436Kb)  |  收藏  |  浏览/下载：146/50  |  提交时间：2018/07/16
Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 189-199
作者:  Li, Mingyue;  Yue, Grace Gar-Lee;  Song, Li-Hua;  Huang, Mao-Bo;  Lee, Julia Kin-Ming;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
浏览  |  Adobe PDF(2333Kb)  |  收藏  |  浏览/下载：201/40  |  提交时间：2018/07/02
Bigelovin  Colorectal Cancer  Metastasis  Tumor Microenvironment  Ll6/stat3 Pathway  
Munronin O, a potential activator for plant resistance 期刊论文
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2018, 卷号: 146, 页码: 13-18
作者:  Yan, Ying;  Tang, Lei;  Hu, Jiaqi;  Wang, Jianta;  Adelakun, Tiwalade Adegoke;  Yang, Dongqiong;  Di, Yingtong;  Zhang, Yu;  Hao, Xiaojiang
浏览  |  Adobe PDF(1146Kb)  |  收藏  |  浏览/下载：604/159  |  提交时间：2018/06/11
Limonoids  Munronia Henryi Harms  Tobacco Mosaic Virus  Antiviral Activity  Plant Resistance  
Enzyme-Assisted Extraction Optimization, Characterization and Antioxidant Activity of Polysaccharides from Sea Cucumber Phyllophorus proteus 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 590
作者:  Qin, Yujing;  Yuan, Qingxia;  Zhang, Yuexing;  Li, Jialu;  Zhu, Xinjiao;  Zhao, Lingling;  Wen, Jing;  Liu, Jikai;  Zhao, Longyan;  Zhao, Jinhua
浏览  |  Adobe PDF(5270Kb)  |  收藏  |  浏览/下载：276/73  |  提交时间：2018/07/02
Sea Cucumber  Polysaccharide  Enzyme-assisted Extraction  Characterization  Antioxidant Activity  
Structure-Activity Relationship of Xanthones as Inhibitors of Xanthine Oxidase 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 2, 页码: 365
作者:  Zhou, Ling-Yun;  Peng, Jia-Le;  Wang, Jun-Ming;  Geng, Yuan-Yuan;  Zuo, Zhi-Li;  Hua, Yan
浏览  |  Adobe PDF(2334Kb)  |  收藏  |  浏览/下载：222/45  |  提交时间：2018/05/08
Xanthone  Xanthine Oxidase Inhibitors  3d-qsar  Gout  
A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 2, 页码: 325
作者:  Qi, Jing-Jing;  Yan, Yong-Ming;  Cheng, Li-Zhi;  Liu, Bao-Hua;  Qin, Fu-Ying;  Cheng, Yong-Xian
浏览  |  Adobe PDF(1181Kb)  |  收藏  |  浏览/下载：166/36  |  提交时间：2018/05/08
Lycium Ruthenicun  Flavonoid  Ruthenicunoid a  Sirt1  
Synthesis of Fucosylated Chondroitin Sulfate Glycoclusters: A Robust Route to New Anticoagulant Agents 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2018, 卷号: 24, 期号: 7, 页码: 1694-1700
作者:  Zhang, Xiao;  Yao, Wang;  Xu, Xiaojiang;  Sun, Huifang;  Zhao, Jinhua;  Meng, Xiangbao;  Wu, Mingyi;  Li, Zhongjun
浏览  |  Adobe PDF(1719Kb)  |  收藏  |  浏览/下载：203/54  |  提交时间：2018/05/08
Anticoagulants  Drug Discovery  Glycoconjugates  Structure-activity Relationships  Synthesis Design