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Synthesis of Fucosylated Chondroitin Sulfate Nonasaccharide as a Novel Anticoagulant Targeting Intrinsic Factor Xase Complex 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 39, 页码: 12880-12885
Authors:  Zhang, Xiao;  Liu, Huiying;  Lin, Lisha;  Yao, Wang;  Zhao, Jinhua;  Wu, Mingyi;  Li, Zhongjun
View  |  Adobe PDF(1568Kb)  |  Favorite  |  View/Download：64/7  |  Submit date：2018/10/22
Anticoagulants  Drug Discovery  Fucosylated Chondroitin Sulfate  Glycosaminoglycans  Oligosaccharides  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
Authors:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
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Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
Structural analysis and anticoagulant activities of three highly regular fucan sulfates as novel intrinsic factor Xase inhibitors 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 195, 页码: 257-266
Authors:  Shang, Feineng;  Mou, Rongrong;  Zhang, Zhidong;  Gao, Na;  Lin, Lisha;  Li, Zhongkun;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(2021Kb)  |  Favorite  |  View/Download：158/8  |  Submit date：2018/07/16
Fucan Sulfate  Chemical Structure  Anticoagulant  Polysaccharide  Sea Cucumber  
Synthesis and anticoagulation studies of "short-armed" fucosylated chondroitin sulfate glycoclusters 期刊论文
CARBOHYDRATE RESEARCH, 2018, 卷号: 467, 页码: 45-51
Authors:  Liu, Huiying;  Zhang, Xiao;  Wu, Mingyi;  Li, Zhongjun
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Fucosylated Chondroitin Sulfate  Glycocluster  Glycosaminoglycan  Anticoagulant  Carbohydrate  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
Authors:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(3117Kb)  |  Favorite  |  View/Download：68/9  |  Submit date：2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase  
Structural analysis and biological activity of a highly regular glycosaminoglycan from Achatina fulica 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 181, 页码: 433-441
Authors:  Liu, Jie;  Zhou, Lutan;  He, Zhicheng;  Gao, Na;  Shang, Feineng;  Xu, Jianping;  Li, Zi;  Yang, Zengming;  Wu, Mingyi;  Zhao, Jinhua
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Snail  Glycosaminoglycan  Chemical Structure  Heparin  Anticoagulant  
Synthesis of Fucosylated Chondroitin Sulfate Glycoclusters: A Robust Route to New Anticoagulant Agents 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2018, 卷号: 24, 期号: 7, 页码: 1694-1700
Authors:  Zhang, Xiao;  Yao, Wang;  Xu, Xiaojiang;  Sun, Huifang;  Zhao, Jinhua;  Meng, Xiangbao;  Wu, Mingyi;  Li, Zhongjun
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Anticoagulants  Drug Discovery  Glycoconjugates  Structure-activity Relationships  Synthesis Design  
Modulating the degree of fucosylation of fucosylated chondroitin sulfate enhances heparin cofactor II-dependent thrombin inhibition 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154, 页码: 133-143
Authors:  Xu, Li;  Gao, Na;  Xiao, Chuang;  Lin, Lisha;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
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Discovery of FIXa inhibitors by combination of pharmacophore modeling, molecular docking, and 3D-QSAR modeling 期刊论文
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2018, 卷号: 38, 期号: 3, 页码: 246-255
Authors:  Li, Penghua;  Peng, Jiale;  Zhou, Yeheng;  Li, Yaping;  Liu, XingYong;  Wang, LiangLiang;  Zuo, ZhiLi
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FGs 影响表面激活系统的活性与构效关系研究 学位论文
: 中国科学院大学, 2017
Authors:  林丽莎
Adobe PDF(5582Kb)  |  Favorite  |  View/Download：16/0  |  Submit date：2019/06/14