A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun
Qi, Jing-Jing1,2; Yan, Yong-Ming3; Cheng, Li-Zhi3; Liu, Bao-Hua3; Qin, Fu-Ying2,3; Cheng, Yong-Xian1,2,3,4
2018-02-01
Source PublicationMOLECULES
ISSN1420-3049
Volume23Issue:2Pages:325
AbstractA novel flavonoid glucoside, ruthenicunoid A (1), together with eight known substances, were isolated from the fruits of Lycium ruthenicun Murr. Their structures were elucidated by extensive spectroscopic data and chemical methods. Especially, the absolute configuration of glucose residue in 1 was assigned by acid hydrolysis followed by derivatization and GC analysis. Biological evaluation towards Sirtuin 1 (SIRT1) found that compounds 1 and 2 exhibit inhibitory activity against SIRT1 in a concentration-dependent manner, indicating its potential on SIRT1-associated disorders.
KeywordLycium Ruthenicun Flavonoid Ruthenicunoid a Sirt1
DOI10.3390/molecules23020325
Language英语
WOS IDWOS:000426436300105
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/60442
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Yunnan Univ Tradit Chinese Med, Sch Pharm, Kunming 650500, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
3.Shenzhen Univ Hlth Sci Ctr, Sch Med, Sch Pharmaceut Sci, Guangdong Key Lab Genome Stabil & Dis Prevent, Shenzhen 518060, Peoples R China
4.Henan Univ Chinese Med, Sch Pharm, Zhengzhou 450008, Henan, Peoples R China
Recommended Citation
GB/T 7714
Qi, Jing-Jing,Yan, Yong-Ming,Cheng, Li-Zhi,et al. A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun[J]. MOLECULES,2018,23(2):325.
APA Qi, Jing-Jing,Yan, Yong-Ming,Cheng, Li-Zhi,Liu, Bao-Hua,Qin, Fu-Ying,&Cheng, Yong-Xian.(2018).A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun.MOLECULES,23(2),325.
MLA Qi, Jing-Jing,et al."A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun".MOLECULES 23.2(2018):325.
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