A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun
Qi, Jing-Jing1,2; Yan, Yong-Ming3; Cheng, Li-Zhi3; Liu, Bao-Hua3; Qin, Fu-Ying2,3; Cheng, Yong-Xian1,2,3,4
2018-02-01
发表期刊MOLECULES
ISSN1420-3049
卷号23页码:325
摘要A novel flavonoid glucoside, ruthenicunoid A (1), together with eight known substances, were isolated from the fruits of Lycium ruthenicun Murr. Their structures were elucidated by extensive spectroscopic data and chemical methods. Especially, the absolute configuration of glucose residue in 1 was assigned by acid hydrolysis followed by derivatization and GC analysis. Biological evaluation towards Sirtuin 1 (SIRT1) found that compounds 1 and 2 exhibit inhibitory activity against SIRT1 in a concentration-dependent manner, indicating its potential on SIRT1-associated disorders.
关键词Lycium Ruthenicun Flavonoid Ruthenicunoid a Sirt1
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/60442
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Yunnan Univ Tradit Chinese Med, Sch Pharm, Kunming 650500, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
3.Shenzhen Univ Hlth Sci Ctr, Sch Med, Sch Pharmaceut Sci, Guangdong Key Lab Genome Stabil & Dis Prevent, Shenzhen 518060, Peoples R China
4.Henan Univ Chinese Med, Sch Pharm, Zhengzhou 450008, Henan, Peoples R China
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Qi, Jing-Jing,Yan, Yong-Ming,Cheng, Li-Zhi,et al. A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun[J]. MOLECULES,2018,23(2):325.
APA Qi, Jing-Jing,Yan, Yong-Ming,Cheng, Li-Zhi,Liu, Bao-Hua,Qin, Fu-Ying,&Cheng, Yong-Xian.(2018).A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun.MOLECULES,23(2),325.
MLA Qi, Jing-Jing,et al."A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun".MOLECULES 23.2(2018):325.
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