A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun

doi:10.3390/molecules23020325

	A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun
	Qi, Jing-Jing 1,2; Yan, Yong-Ming 3; Cheng, Li-Zhi 3; Liu, Bao-Hua 3; Qin, Fu-Ying 2,3; Cheng, Yong-Xian 1,2,3,4
	2018-02-01
发表期刊	MOLECULES
ISSN	1420-3049
卷号	23 期号:2 页码:325
摘要	A novel flavonoid glucoside, ruthenicunoid A (1), together with eight known substances, were isolated from the fruits of Lycium ruthenicun Murr. Their structures were elucidated by extensive spectroscopic data and chemical methods. Especially, the absolute configuration of glucose residue in 1 was assigned by acid hydrolysis followed by derivatization and GC analysis. Biological evaluation towards Sirtuin 1 (SIRT1) found that compounds 1 and 2 exhibit inhibitory activity against SIRT1 in a concentration-dependent manner, indicating its potential on SIRT1-associated disorders.
关键词	Lycium Ruthenicun Flavonoid Ruthenicunoid a Sirt1
DOI	10.3390/molecules23020325
语种	英语
WOS记录号	WOS:000426436300105
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/60442
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Yunnan Univ Tradit Chinese Med, Sch Pharm, Kunming 650500, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 3.Shenzhen Univ Hlth Sci Ctr, Sch Med, Sch Pharmaceut Sci, Guangdong Key Lab Genome Stabil & Dis Prevent, Shenzhen 518060, Peoples R China 4.Henan Univ Chinese Med, Sch Pharm, Zhengzhou 450008, Henan, Peoples R China
推荐引用方式 GB/T 7714	Qi, Jing-Jing,Yan, Yong-Ming,Cheng, Li-Zhi,et al. A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun[J]. MOLECULES,2018,23(2):325.
APA	Qi, Jing-Jing,Yan, Yong-Ming,Cheng, Li-Zhi,Liu, Bao-Hua,Qin, Fu-Ying,&Cheng, Yong-Xian.(2018).A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun.MOLECULES,23(2),325.
MLA	Qi, Jing-Jing,et al."A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun".MOLECULES 23.2(2018):325.

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