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Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
浏览  |  Adobe PDF(11543Kb)  |  收藏  |  浏览/下载:12/2  |  提交时间:2024/07/17
Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 106375
作者:  Peng,Xingrong;  Luo,Rongcan;  Ran,Xiaoqian;  Guo,Yarong;  Yao,Yong-Gang;  Qiu,Minghua
Adobe PDF(3003Kb)  |  收藏  |  浏览/下载:11/4  |  提交时间:2024/07/22
Ganoderma  Ganoderma applanatum  Triterpenoid  Autophagy  Tau pathology  Alzheimer?s disease  LANOSTANE-TYPE TRITERPENOIDS  ALZHEIMERS-DISEASE  FRUITING BODIES  NEURODEGENERATION  ACID  
Sesquiterpenes from Carpesium faberi triggered ROS-induced apoptosis and protective autophagy in hepatocellular carcinoma cells 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113805
作者:  Yan,Ying;  Chen,Jie;  Peng,Mingyou;  Zhang,Xiong;  Feng,Enming;  Li,Qindan;  Guo,Bing;  Ding,Xiao;  Zhang,Yu;  Tang,Lei
浏览  |  Adobe PDF(4017Kb)  |  收藏  |  浏览/下载:11/5  |  提交时间:2024/07/25
Carpesium faberi (compositae)  Sesquiterpenes  Structural elucidation  Cytotoxic activities  Autophagy  LACTONE DIMERS  MYRRHANONE C  XANTHANOLIDES  TRITERPENE  HYBRIDS  ESTERS  
Tripterygium wilfordii protects against an animal model of autoimmune hepatitis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 309, 页码: 116365
作者:  Zhang,Ting;  Rao,Qianru;  Dai,Manyun;  Zhao,Qi;  Li,Fei
Adobe PDF(13950Kb)  |  收藏  |  浏览/下载:8/2  |  提交时间:2024/07/25
Tripterygium wilfordii tablets  Celastrol  Concanavalin A  Autophagy  TFEB  PXR  PREGNANE-X-RECEPTOR  CHOLESTATIC LIVER-INJURY  CELASTROL PROTECTS  AUTOPHAGY  OBESITY  DYSFUNCTION  DOMAIN  
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
作者:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
Adobe PDF(5266Kb)  |  收藏  |  浏览/下载:42/13  |  提交时间:2024/05/09
Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1088
作者:  Yan,Ying;  Zhou,Qi;  Ran,Xiaoqian;  Lu,Qingyun;  Zhang,Cuishan;  Peng,Mingyou;  Tang,Lei;  Luo,Rongcan;  Di,Yingtong;  Hao,Xiaojiang
Adobe PDF(11343Kb)  |  收藏  |  浏览/下载:55/15  |  提交时间:2024/05/09
euphjatrophane  Euphorbia peplus  jatrophane diterpenoid  autophagy  Tau pathology  UBIQUITIN-PROTEASOME SYSTEM  MULTIDRUG-RESISTANCE  BIOLOGICAL-ACTIVITY  ALZHEIMERS-DISEASE  MODULATORS  CELLS  
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
作者:  Ran,Xiaoqian;  Lu,Qing-Yun;  Li,Ying-Yao;  Pu,Xue-Xue;  Guo,Yarong;  Yuan,Ming-Rui;  Guan,Shi-Peng;  Sun,Mao;  Jiao,Lijin;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang;  Luo,Rongcan
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Euphorbia peplus L  Euphorbiaceae  Ent-abietane diterpenoid  Euphejolkinolide A  Autophagy-lysosomal pathway  ALZHEIMERS-DISEASE  TAU PATHOLOGY  NEURODEGENERATION  DITERPENOIDS  INHIBITION  MECHANISMS  APOPTOSIS  CELASTROL  PROTEIN  SYSTEM  
20-去氧巨大戟醇酯衍生物合成及其构效关系研究 学位论文
: 中国科学院大学, 2022
作者:  张翠珊
Adobe PDF(3951Kb)  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/05/14
20-去氧巨大戟醇酯,自噬,结构修饰,构效关系  20-Deoxyingenane esters, Autophagy, Structural modification, SAR  
南欧大戟中大戟二萜类成分及其自噬相关活性评价 学位论文
: 中国科学院大学, 2022
作者:  李盈瑶
Adobe PDF(4112Kb)  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/05/14
南欧大戟  Euphorbia peplus  大戟二萜  Euphorbia diterpenoids  自噬-溶酶体  autophagy-lysosomal  
Nujiangexanthone A Inhibits Cervical Cancer Cell Proliferation by Promoting Mitophagy 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 10, 页码: 2858
作者:  Feng,Jiling;  Mansouripour,Anahitasadat;  Xi,Zhichao;  Zhang,Li;  Xu,Gang;  Zhou,Hua;  Xu,Hongxi
收藏  |  浏览/下载:101/0  |  提交时间:2022/04/02
nujiangexanthone A  mitophagy  ATG7  starvation  MITOCHONDRIAL DYSFUNCTION  GARCINIA-NUJIANGENSIS  COMPOUND  AUTOPHAGY  NUJIANGEXATHONE  ACTIVATION