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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
浏览  |  Adobe PDF(17974Kb)  |  收藏  |  浏览/下载:69/19  |  提交时间:2024/07/17
Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Tripterygium wilfordii protects against an animal model of autoimmune hepatitis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 309, 页码: 116365
作者:  Zhang,Ting;  Rao,Qianru;  Dai,Manyun;  Zhao,Qi;  Li,Fei
浏览  |  Adobe PDF(13950Kb)  |  收藏  |  浏览/下载:39/13  |  提交时间:2024/07/25
Tripterygium wilfordii tablets  Celastrol  Concanavalin A  Autophagy  TFEB  PXR  PREGNANE-X-RECEPTOR  CHOLESTATIC LIVER-INJURY  CELASTROL PROTECTS  AUTOPHAGY  OBESITY  DYSFUNCTION  DOMAIN  
Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
作者:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
收藏  |  浏览/下载:390/0  |  提交时间:2022/07/15
Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
雷公藤制剂对消化系统的毒性机理研究 学位论文
: 中国科学院大学, 2022
作者:  代曼云
Adobe PDF(10574Kb)  |  收藏  |  浏览/下载:18/0  |  提交时间:2024/05/14
代谢组学,雷公藤,药源性肝损伤,消化性溃疡,FXR,ET-1, 肠道血管屏障  Metabolomics, Tripterygium wilfordii, Drug-induced liver injury, peptic ulcer disease, FXR, ET-1, intestinal vascular barrier.  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
浏览  |  Adobe PDF(2010Kb)  |  收藏  |  浏览/下载:177/19  |  提交时间:2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Triterpenes from Tripterygium wilfordii Hook 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2006, 卷号: 8, 期号: 5, 页码: 425-429
作者:  Yang, J. -H.;  Luo, S. -D.;  Wang, Y-S.;  Zhao, J. -F.;  Zhang, H. -B.;  Li, L.
Adobe PDF(127Kb)  |  收藏  |  浏览/下载:321/178  |  提交时间:2011/11/24
Tripterygium Wilfordii Hook.f  Celastraceae  Triterpenes  Tripterfrielanons A-b  
Insecticidal compounds from Tripterygium wilfordii active against Mythimna separata 期刊论文
ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES, 2004, 卷号: 59, 期号: 5-6, 页码: 421-426
作者:  Luo, DQ;  Zhang, X;  Tian, X;  Liu, JK
浏览  |  Adobe PDF(80Kb)  |  收藏  |  浏览/下载:285/91  |  提交时间:2012/07/25
Tripterygium Wilfordii  Insecticidal Compounds  Mythimna Separata