| Insecticidal compounds from Tripterygium wilfordii active against Mythimna separata | |
| Luo, DQ; Zhang, X; Tian, X; Liu, JK | |
| 2004-05-01 | |
| 发表期刊 | ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
 |
| ISSN | 0939-5075 |
| 卷号 | 59期号:5-6页码:421-426 |
| 摘要 | In the course of screening for novel naturally occurring insecticides from plants, the ethanol extract of the root bark of Tripterygium wilfordii Hook f. was found to show insecticidal activity against larvae of Mythimna separata Walker. Three active compounds were isolated by bioassay-guided fractionation of the extract and characterized as triptolide (1), triptonide (2) and euonine (3) by IR, H-1 and C-13 NMR and mass spectral analysis. Compounds 1 and 2 showed strong contact activity against 3(rd) or 5(th) larvae of M. separata (LD50 1.6 mug/insect for 1, 2.9 mug/insect for 2, no contact activity for 3; LD50 is the lethal dose for 50% mortality). The antifeedant activity against the 3(rd) larvae of M. separata after a 24-h treatment was demonstrated; 1, 2 and 3 gave EC50 (effective concentration causing 50% antifeedance) values of 0.25, 0.35 and 0.02 mm, respectively. 1 and 2 were inferior to the positive control represented by toosendanin (12alpha-acetoxyamoorastatin), 3 was superior to toosendanin. For the ingested toxicity against M. separata, 1 had the more potent activity with an KD50 value of 13.5 mug/g (insect body weight) than toosendanin. This is the first report on insecticidal activity of these three compounds. |
| 关键词 | Tripterygium Wilfordii Insecticidal Compounds Mythimna Separata |
| 学科领域 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000222866600024 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/14455 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China 2.NW Sci Tech Univ Agr & Forestry, Pesticide Res Ctr, Yangling 712100, Shaanxi, Peoples R China 3.Lanzhou Univ, Natl Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Luo, DQ,Zhang, X,Tian, X,et al. Insecticidal compounds from Tripterygium wilfordii active against Mythimna separata[J]. ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES,2004,59(5-6):421-426. |
| APA | Luo, DQ,Zhang, X,Tian, X,&Liu, JK.(2004).Insecticidal compounds from Tripterygium wilfordii active against Mythimna separata.ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES,59(5-6),421-426. |
| MLA | Luo, DQ,et al."Insecticidal compounds from Tripterygium wilfordii active against Mythimna separata".ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES 59.5-6(2004):421-426. |
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