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Cytotoxic and pro-apoptotic effects of botanical drugs derived from the indigenous cultivated medicinal plant Paris polyphylla var. yunnanensis 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1100825
作者:  Yan,Xiu-Xiang;  Zhao,Yan-Qiang;  He,Yun;  Disayathanoowat,Terd;  Pandith,Hataichanok;  Inta,Angkhana;  Yang,Li-Xin
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Paris polyphylla var  yunnanensis  indigenous medicine knowledge  saponins  cytotoxic effects  pro-apoptotic effects  CELL-CYCLE ARREST  STEROIDAL SAPONINS  HEPATOCELLULAR-CARCINOMA  CHEMICAL-CONSTITUENTS  ASSAY  GLYCOSIDES  LEAVES  GROWTH  STEMS  SITES  
A Multiplex PCR System of Novel Microsatellite Loci for Population Genetic Application in Walnuts 期刊论文
PLANTS-BASEL, 2023, 卷号: 12, 期号: 24, 页码: 4101
作者:  Xiahou,Zuo-Ying;  Wambulwa,Moses C.;  Xu,Zu-Chang;  Ye,Lin-Jiang;  Fan,Peng-Zhen;  Magige,Ephie A.;  Luo,Ya-Huang;  Liu,Jie
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genetic diversity  Juglans  microsatellite marker  multiplex PCR  transferability  walnut  CROSS-SPECIES AMPLIFICATION  SSR-MARKERS  JUGLANS-MANDSHURICA  COMPUTER-PROGRAM  DIVERSITY  SOFTWARE  SUCCESS  ASSAY  
Cloning and Functional Characterization of a Squalene Synthase from Paris polyphylla var. yunnanensis 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 7
作者:  Gao,Jian-Xiong;  Chen,Yue-Gui;  Li,De-Sen;  Lin,Liang;  Liu,Yan;  Li,Sheng-Hong
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Paris polyphylla var  Yunnanensis  squalene synthase  steroidal saponins  squalene  in vitro enzymatic assay  MOLECULAR-CLONING  SAPONINS  EXPRESSION  GENE  GLYCOSIDES  PLANTS  SQS  
Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities 期刊论文
TETRAHEDRON, 2021, 卷号: 79, 页码: 131783
作者:  Shi,Bao-Bao;  Wang,Fang;  Chen,Gao;  Schinnerl,Johann;  Zeng,Ying;  Cai,Xiang-Hai
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Stemona mairei  Dihydrostilbenes  Structure elucidation  Quantum chemical calculation  Hypoglycemic activity assay  STILBENOIDS  CONFIGURATION  DERIVATIVES  
A re-evaluation of dilution for eliminating PCR inhibition in soil DNA samples 期刊论文
SOIL BIOLOGY & BIOCHEMISTRY, 2017, 卷号: 106, 页码: 109-118
作者:  Wang,Hang;  Qi,Jinfeng;  Xiao,Derong;  Wang,Zhibao;  Tian,Kun
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Real-time Pcr  Environmental-samples  Extraction  Sediment  Quantification  Optimization  Assay  Pcr  Inhibition  Dilution  Dna Extraction  Microbe  Humic Acid  
Isolation, characterisation, and antioxidant activities of flavonoids from chufa (Eleocharis tuberosa) peels 期刊论文
FOOD CHEMISTRY, 2014, 卷号: 164, 页码: 30-35
作者:  Luo, Yanghe;  Li, Xingren;  He, Juan;  Su, Jia;  Peng, Liyan;  Wu, Xingde;  Du, Runan;  Zhao, Qinshi;  Zhao, QS (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China.;  qinshizhao@mail.kib.ac.cn
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Chufa Peels  Eleocharis Tuberosa  Flavonoids  Antioxidant Activity  Dpph Assay  
Heterodimeric ent-Kauranoids from Isodon tenuifolius 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2014, 卷号: 77, 期号: 11, 页码: 2444-2453
作者:  Yang, Jian-Hong;  Wang, Wei-Guang;  Du, Xue;  He, Fei;  Zhang, Hai-Bo;  Li, Xiao-Nian;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
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Immunosuppressive Polyketides  5-aminolevulinic Acid  Assay  Marine-associated Fungus  Daldinia Eschscholzii  Secondary Metabolites  Hydrolysis  Gc Analysis  X-ray Diffraction Analysis  
Development of a fluorescence-based HIV-1 integrase DNA binding assay for identification of novel HIV-1 integrase inhibitors 期刊论文
ANTIVIRAL RESEARCH, 2013, 卷号: 98, 期号: 3, 页码: 441-448
作者:  Han, Ying-Shan;  Xiao, Wei-Lie;  Quashie, Peter K.;  Mesplede, Thibault;  Xu, Hongtao;  Deprez, Eric;  Delelis, Olivier;  Pu, Jian-Xin;  Sun, Han-Dong;  Wainberg, Mark A.
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Hiv-1 Integrase Inhibitors  Integrase Dna Binding  Fluorescent Assay  
Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 4, 页码: 702-709
作者:  Chen, Guo-Dong;  Chen, Ying;  Gao, Hao;  Shen, Li-Qing;  Wu, Yang;  Li, Xiao-Xia;  Li, Yan;  Guo, Liang-Dong;  Cen, Ying-Zhou;  Yao, Xin-Sheng
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Cercospora-beticola Toxins  Humicola Sp  Proliferation  Assay  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
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One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.