Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum
Chen, Guo-Dong1,4; Chen, Ying1; Gao, Hao1; Shen, Li-Qing1; Wu, Yang1; Li, Xiao-Xia1; Li, Yan2; Guo, Liang-Dong3; Cen, Ying-Zhou4; Yao, Xin-Sheng1
通讯作者Gao, H (reprint author), Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China. ; tghao@jnu.edu.cn ; tyaoxs@jnu.edu.cn
2013-04-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号76期号:4页码:702-709
摘要Five new xanthoquinodins, A4-A6 (1-3), B4 (4), and B5 (5), were isolated from the crude extract of the endolichenic fungal strain Chaetomium elatum (No. 63-10-3-1), along with three known xanthoquinodins, A1-A3 (6-8). Their structures were determined by detailed spectroscopic analysis and comparison of the NMR data with those of the closely related compounds previously reported. The absolute configuration of 1 was established by X-ray crystallographic analysis and ECD calculation. The cytotoxic activity of all compounds was tested against HL-60, SMMC-7721, A-549, MCF-7, and SW480 human cancer cell lines.
关键词Cercospora-beticola Toxins Humicola Sp Proliferation Assay
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np400041y
收录类别SCI ; IC
语种英语
WOS记录号WOS:000318264700030
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16551
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China
2.Chinese Acad Sci, State Key Lab Photochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650204, Peoples R China
3.Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100190, Peoples R China
4.Jinan Univ, Dept Chem, Guangzhou 510632, Guangdong, Peoples R China
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Chen, Guo-Dong,Chen, Ying,Gao, Hao,et al. Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(4):702-709.
APA Chen, Guo-Dong.,Chen, Ying.,Gao, Hao.,Shen, Li-Qing.,Wu, Yang.,...&Yao, Xin-Sheng.(2013).Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum.JOURNAL OF NATURAL PRODUCTS,76(4),702-709.
MLA Chen, Guo-Dong,et al."Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum".JOURNAL OF NATURAL PRODUCTS 76.4(2013):702-709.
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