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题名: Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum
作者: Chen, Guo-Dong1, 4; Chen, Ying1; Gao, Hao1; Shen, Li-Qing1; Wu, Yang1; Li, Xiao-Xia1; null(李艳)2; Guo, Liang-Dong3; Cen, Ying-Zhou4; Yao, Xin-Sheng1
刊名: JOURNAL OF NATURAL PRODUCTS
关键词: CERCOSPORA-BETICOLA TOXINS ; HUMICOLA SP ; PROLIFERATION ; ASSAY
英文摘要: Five new xanthoquinodins, A4-A6 (1-3), B4 (4), and B5 (5), were isolated from the crude extract of the endolichenic fungal strain Chaetomium elatum (No. 63-10-3-1), along with three known xanthoquinodins, A1-A3 (6-8). Their structures were determined by detailed spectroscopic analysis and comparison of the NMR data with those of the closely related compounds previously reported. The absolute configuration of 1 was established by X-ray crystallographic analysis and ECD calculation. The cytotoxic activity of all compounds was tested against HL-60, SMMC-7721, A-549, MCF-7, and SW480 human cancer cell lines.
出版日期: 2013-04-01
卷号: 76, 期号:4, 页码:702-709
DOI标识: 10.1021/np400041y
语种: 英语
收录类别: SCI ; IC
学科分类: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
ISSN号: 0163-3864
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/16551
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China
2.Chinese Acad Sci, State Key Lab Photochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650204, Peoples R China
3.Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100190, Peoples R China
4.Jinan Univ, Dept Chem, Guangzhou 510632, Guangdong, Peoples R China

Recommended Citation:
Chen, Guo-Dong; Chen, Ying; Gao, Hao; Shen, Li-Qing; Wu, Yang; Li, Xiao-Xia; Li, Yan; Guo, Liang-Dong; Cen, Ying-Zhou; Yao, Xin-Sheng.Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum,JOURNAL OF NATURAL PRODUCTS,2013,76(4):702-709
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