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Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
作者:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
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Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Phomopsischalins A-C, polycyclic-fused cytochalasins from the endophytic fungus Phomopsis sp. shj2 and their abilities to induce lysosomal function 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 9, 页码: 2218-2225
作者:  Chen,Rong;  Guo,Li-Jing;  Li,Xue-Dan;  Li,Xing-Ren;  Hu,Kun;  Tang,Jian-Wei;  Ye,Zhen-Nan;  Yan,Bing-Chao;  Puno,Pema-Tenzin
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Abietane derived diterpenoids as Cav3.1 antagonists from Salvia digitaloides 期刊论文
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 4, 页码: 107737
作者:  Zhao,Jianjun;  Du,Shuzong;  Hu,Kun;  Hu,Yali;  Xia,Fan;  Ye,Yansong;  Yang,Jian;  Nian,Yin;  Xu,Gang
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10-Methylated 6  7  6 carbon ring system  Icetexane  Diterpenoid  Salvia digitaloides  Ca v 3  1 low voltage -gated Ca 2+channel  (LVGCC)  ROOTS  TANSHINLACTONE  CONSTITUENTS  ELUCIDATION  INHIBITORS  CHANNELS  SKELETON  SYSTEM  
Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106512
作者:  Tan,Qian;  Hu,Kun;  Li,Xiao-Nian;  Yang,Xing-Zhi;  Sun,Han-Dong;  Puno,Pema-Tenzin
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Isodon wardii  ent-Kauranoids  Cytotoxicity  Apoptosis  Cell cycle  
Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 11, 期号: 1, 页码: 37-46
作者:  Dai,Jia-Meng;  Yan,Bing-Chao;  Kong,Ling-Mei;  Hu,Kun;  Li,Xing-Ren;  Li,Xiao-Nian;  Sun,Han-Dong;  Li,Yan;  Puno,Pema-Tenzin
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ENT-KAURANE DITERPENOIDS  ABIETANE DITERPENOIDS  A-D  DIMERS  OXIDATION  CYCLOADDUCTS  ACTIVATION  LIGANDS  IBX  
Four new lanostane triterpenoids featuring extended pi-conjugated systems from the stems of Kadsura coccinea. 期刊论文
Natural products and bioprospecting, 2023, 卷号: 13, 期号: 1, 页码: 12-12
作者:  Zhang, Qi-Qi;  Hu, Kun;  Sun, Han-Dong;  Puno, Pema-Tenzin
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Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel 期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
作者:  Hu,Guilin;  Dong,Ding;  Du,Shuzong;  Peng,Xingrong;  Wu,Mingkun;  Shi,Qiangqiang;  Hu,Kun;  Hong,Defu;  Wang,Xiaoyuan;  Zhou,Lin;  Nian,Yin;  Qiu,Minghua
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Coffea arabica L  Roasted coffee  Coffee diterpenoid  Cafestol  Kahweol  T-type Ca2+ channels  Ca(v)3.1 low voltage-gated Ca2+ channel  Ca(v)3.1 inhibitors  CALCIUM-CHANNELS  CAFESTOL  KAHWEOL  PHYSIOLOGY  ESTERS  NOMENCLATURE  PHARMACOLOGY  APOPTOSIS  FURANS  
Arbuscular mycorrhizal trees influence the latitudinal beta-diversity gradient of tree communities in forests worldwide 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 3137
作者:  Zhong,Yonglin;  Chu,Chengjin;  Myers,Jonathan A.;  Gilbert,Gregory S.;  Lutz,James A.;  Stillhard,Jonas;  Zhu,Kai;  Thompson,Jill;  Baltzer,Jennifer L.;  He,Fangliang;  LaManna,Joseph A.;  Davies,Stuart J.;  Aderson-Teixeira,Kristina J.;  Burslem,David F. R. P.;  Alonso,Alfonso;  Chao,Kuo-Jung;  Wang,Xugao;  Gao,Lianming;  Orwig,David A.;  Yin,Xue;  Sui,Xinghua;  Su,Zhiyao;  Abiem,Iveren;  Bissiengou,Pulcherie;  Bourg,Norm;  Butt,Nathalie;  Cao,Min;  Chang-Yang,Chia-Hao;  Chao,Wei-Chun;  Chapman,Hazel;  Chen,Yu-Yun;  Coomes,David A.;  Cordell,Susan;  de Oliveira,Alexandre A.;  Du,Hu;  Fang,Suqin;  Giardina,Christian P.;  Hao,Zhanqing;  Hector,Andrew;  Hubbell,Stephen P.;  Janik,David;  Jansen,Patrick A.;  Jiang,Mingxi;  Jin,Guangze;  Kenfack,David;  Kral,Kamil;  Larson,Andrew J.;  Li,Buhang;  Li,Xiankun;  Li,Yide;  Lian,Juyu;  Lin,Luxiang;  Liu,Feng;  Liu,Yankun;  Liu,Yu;  Luan,Fuchen;  Luo,Yahuang;  Ma,Keping;  Malhi,Yadvinder;  McMahon,Sean M.;  McShea,William;  Memiaghe,Herve;  Mi,Xiangcheng;  Morecroft,Mike;  Novotny,Vojtech;  O'Brien,Michael J.;  den Ouden,Jan;  Parker,Geoffrey G.;  Qiao,Xiujuan;  Ren,Haibao;  Reynolds,Glen;  Samonil,Pavel;  Sang,Weiguo;  Shen,Guochun;  Shen,Zhiqiang;  Song,Guo-Zhang Michael;  Sun,I-Fang;  Tang,Hui;  Tian,Songyan;  Uowolo,Amanda L.;  Uriarte,Maria;  Wang,Bin;  Wang,Xihua;  Wang,Youshi;  Weiblen,George D.;  Wu,Zhihong;  Xi,Nianxun;  Xiang,Wusheng;  Xu,Han;  Xu,Kun;  Ye,Wanhui;  Yu,Mingjian;  Zeng,Fuping;  Zhang,Minhua;  Zhang,Yingming;  Zhu,Li;  Zimmerman,Jess K.
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NEGATIVE DENSITY-DEPENDENCE  NESTEDNESS  TEMPERATURE  COMPONENTS  TURNOVER  PLANTS  FUNGI  ASSOCIATIONS  ECOLOGY  NETWORK  
FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105338
作者:  Peng,Xing-Rong;  Wang,Qian;  Wang,Hui-Rong;  Hu,Kun;  Xiong,Wen-Yong;  Qiu,Ming-Hua
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Ganoderma applanatum  Meroterpenoid dimers  Molecular docking  Anti-lipogenesis  FPR2-based inflammation  INDUCED INSULIN-RESISTANCE  ADIPOCYTE DIFFERENTIATION  OBESITY  INFLAMMATION  DEFICIENCY  MACROPHAGES  ACTIVATION  EXPRESSION  LIGAND  MICE  
Chaetolactam A, an Azaphilone Derivative from the Endophytic Fungus Chaetomium sp. g1 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 1, 页码: 475-483
作者:  Zu,Wen-Yu;  Tang,Jian-Wei;  Hu,Kun;  Zhou,Yuan-Fei;  Gou,Lei-Lei;  Su,Xiao-Zheng;  Lei,Xinxiang;  Sun,Han-Dong;  Puno,Pema-Tenzin
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MASS-SPECTROMETRY  A-D  CASPASE-3  H-1