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Leucosceptrane Sesterterpenoids as a New Type of Natural Immunosuppressive Agents in Treating Sepsis 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 67, 期号: 1, 页码: 513-528
作者:  Guo,Kai;  Zhou,Ting-Ting;  Luo,Shi-Hong;  Liu,Yan-Chun;  Liu,Yan;  Li,Sheng-Hong
Adobe PDF(12263Kb)  |  收藏  |  浏览/下载：185/31  |  提交时间：2024/07/10
GLANDULAR TRICHOMES  PRODUCTS  HARBOR  CANUM  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
作者:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
收藏  |  浏览/下载：240/0  |  提交时间：2022/04/02
Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 11, 页码: 7404-7421
作者:  Zhou,Zongyuan;  Li,Yiming;  Ma,Xiaofang;  Cao,Biyun;  Peng,Ting;  Sheng,Yuwen;  Peng,Huipan;  Li,Runze;  Cao,Yu;  Xi,Ruiying;  Li,Fu;  Wang,Mengru;  Sun,Handong;  Zhang,Guolin;  Zhang,Hongbin;  Hu,Kaifeng;  Xiao,Weilie;  Wang,Fei
收藏  |  浏览/下载：215/0  |  提交时间：2022/04/02
GOMISIN-A  DIBENZOCYCLOOCTADIENE LIGNANS  SCHISANDRA-CHINENSIS  MASS-SPECTROMETRY  MIRNA EXPRESSION  DOWN-REGULATION  NONCODING RNA  MICRORNA  LIVER  DICER  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2630Kb)  |  收藏  |  浏览/下载：332/105  |  提交时间：2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Design and synthesis of novel artemisinin hybrids with potent activities against human colorectal cancer cells in vitro and in vivo (vol 182, 111665, 2019) 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020
作者:  Wang, Liang-Liang;  Kong, Lingmei;  Liu, Hui;  Zhang, Yunqin;  Zhang, Li;  Liu, Xingyong;  Yuan, Feng;  Li, Yan;  Zuo, Zhili
浏览  |  Adobe PDF(169Kb)  |  收藏  |  浏览/下载：239/50  |  提交时间：2021/01/05
Congenetic Hybrids Derived from Dearomatized Isoprenylated Acylphloroglucinol with Opposite Effects on Ca(v)3.1 Low Voltage Gated Ca2+ Channel 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020
作者:  Ye, Yan-Song;  Li, Wen-Yan;  Du, Shu-Zong;  Yang, Jian;  Nian, Yin;  Xu, Gang
浏览  |  Adobe PDF(2605Kb)  |  收藏  |  浏览/下载：263/51  |  提交时间：2021/01/05
The discovery, design and synthesis of potent agonists of adenylyl cyclase type 2 by virtual screening combining biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020
作者:  Xu, Guowei;  Yang, Yaqing;  Yang, Yanming;  Song, Gao;  Li, Shanshan;  Zhang, Jiajun;  Yang, Weimin;  Wang, Liang-Liang;  Weng, Zhiying;  Zuo, Zhili
浏览  |  Adobe PDF(2526Kb)  |  收藏  |  浏览/下载：258/49  |  提交时间：2021/01/05
Rhodamine B-based fluorescent probes for molecular mechanism study of the anti-influenza activity of pentacyclic triterpenes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020
作者:  Li, Man;  Yuan, Lan;  Chen, Yingying;  Ma, Wenxiao;  Ran, Fuxiang;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
浏览  |  Adobe PDF(2312Kb)  |  收藏  |  浏览/下载：272/68  |  提交时间：2021/01/05
Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 10
作者:  Wang, Liang-Liang;  Kong, Lingmei;  Liu, Hui;  Zhang, Yunqin;  Zhang, Li;  Liu, Xingyong;  Yuan, Feng;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：246/0  |  提交时间：2020/03/02
Artemisinin  Quinazoline  Hybridization  Colorectal cancer  Chemotherapy  
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:  Deng, Guogang;  Zhou, Bei;  Wang, Jing;  Chen, Zhuo;  Gong, Liang;  Gong, Yaxiao;  Wu, Dongmei;  Li, Yan;  Zhang, Hongbin;  Yang, Xiaodong
浏览  |  Adobe PDF(1727Kb)  |  收藏  |  浏览/下载：482/66  |  提交时间：2019/07/29
Diosgenin  Cholesterol  Dehydroepiandrosterone  Imidazolium salt  Antitumor activities  Structure-activity relationships