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Synthesis, structure activity relationship and in vitro anti-influenza virus activity of novel polyphenol-pentacyclic triterpene conjugates 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163, 页码: 560-568
作者:  Li, Haiwei;  Li, Man;  Xu, Renyang;  Wang, Shouxin;  Zhang, Yongmin;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
浏览  |  Adobe PDF(1830Kb)  |  收藏  |  浏览/下载：136/27  |  提交时间：2019/03/25
Influenza virus  Pentacyclic triterpene  Polyphenol  Entry inhibitor  Hemagglutinin  
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：259/45  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
作者:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
收藏  |  浏览/下载：349/0  |  提交时间：2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization  
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 期号: 0, 页码: 381-393
作者:  Yang, Tong-Hua;  Ma, Yun-Bao;  Geng, Chang-An;  Yan, De-Xiu;  Huang, Xiao-Yan;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2088Kb)  |  收藏  |  浏览/下载：194/68  |  提交时间：2018/10/04
Depression  Magnolol Derivatives  Mt1/2 Receptors  Metabolites  Monoamine Neurotransmitter