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Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
浏览  |  Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：165/34  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
作者:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
浏览  |  Adobe PDF(3138Kb)  |  收藏  |  浏览/下载：789/145  |  提交时间：2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 9, 页码: 10203-10214
作者:  Kong, Ling-Mei;  Feng, Tao;  Wang, Yuan-Yuan;  Li, Xing-Yao;  Ye, Zhen-Nan;  An, Tao;  Qing, Chen;  Luo, Xiao-Dong;  Li, Yan
浏览  |  Adobe PDF(7290Kb)  |  收藏  |  浏览/下载：237/51  |  提交时间：2016/08/22
Bisleuconothine a  Inhibitor  Wnt Signaling  Colorectal Cancer Cells  
Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway 期刊论文
TETRAHEDRON, 2015, 卷号: 71, 期号: 52, 页码: 9673-9678
作者:  Chen, Xiao-Qiang;  Zhao, Si-Meng;  Wang, Zhe;  Zeng, Guang-Zhi;  Huang, Mao-Bo;  Tan, Ning-Hua
浏览  |  Adobe PDF(1412Kb)  |  收藏  |  浏览/下载：684/140  |  提交时间：2016/02/01
Rubia Cordifolia  Rubicordins A-c  Cyclopeptides  Cytotoxicity  Nf-kappa b Signaling Pathway  
Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNF alpha and ROS production 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 4, 页码: 1995-2008
作者:  Yu, Xinfang;  Deng, Qipan;  Li, Wei;  Xiao, Lanbo;  Luo, Xiangjian;  Liu, Xiaolan;  Yang, Lifang;  Peng, Songling;  Ding, Zhihui;  Feng, Tao;  Zhou, Jian;  Fan, Jia;  Bode, Ann M.;  Dong, Zigang;  Liu, Jikai;  Cao, Ya;  Liu,JK (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Beijing 100864,Yunnan,Peoples R China.;  jkliu@mail.kib.ac.cn;  ycao98@vip.sina.com
浏览  |  Adobe PDF(2848Kb)  |  收藏  |  浏览/下载：426/57  |  提交时间：2015/06/29
Necoalbaconol  Necroptosis  Ripk  Tnf Alpha  Nf-kappa b Signaling Pathway  Ros  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：282/71  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Adenanthin targets peroxiredoxin I/II to kill hepatocellular carcinoma cells 期刊论文
CELL DEATH & DISEASE, 2014, 卷号: 5, 页码: e1400
作者:  Hou, J-K;  Huang, Y.;  He, W.;  Yan, Z-W;  Fan, L.;  Liu, M-H;  Xiao, W-L;  Sun, H-D;  Chen, G-Q;  Chen,GQ (reprint author),Shandong Jiaotong Univ,Sch Med,Dept Pathophysiol,280 Chong Qing South Rd,Shanghai 200025,Peoples R China.;  huangying@shsmu.edu.cn;  hdsun@mail.kib.ac.cn;  chengq@shsmu.edu.cn
Adobe PDF(4719Kb)  |  收藏  |  浏览/下载：263/65  |  提交时间：2014/11/25
Reactive Oxygen  Cancer-cells  Signaling Pathway  Mechanisms  Apoptosis  Ros  Roles  Death  Prdx1  
Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 7, 页码: e103760
作者:  Kong, Yanjie;  Chen, Jianchao;  Zhou, Zhongmei;  Xia, Houjun;  Qiu, Ming-Hua;  Chen, Ceshi;  Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  qiuminghua@mail.kib.ac.cn;  chenc@mail.kiz.ac.cn
Adobe PDF(3184Kb)  |  收藏  |  浏览/下载：197/38  |  提交时间：2014/11/25
Inhibitory-activity  Signaling Pathway  Carcinoma  Growth  Activation  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：677/103  |  提交时间：2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e73527
作者:  Hu, Rongkuan;  Yan, Huan;  Hao, Xiaojiang;  Liu, Haiyang;  Wu, Jiarui
浏览  |  Adobe PDF(1041Kb)  |  收藏  |  浏览/下载：555/75  |  提交时间：2013/10/16
Activated Protein-kinase  Fatty-acid Oxidation  Respiratory Complex-i  Insulin-resistance  Malonyl-coa  Signaling Pathways  Glucose-uptake  L6 Myotubes  Hepg2 Cells  Metformin