Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway

doi:10.1016/j.tet.2015.10.044

	Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway
	Chen, Xiao-Qiang; Zhao, Si-Meng; Wang, Zhe; Zeng, Guang-Zhi; Huang, Mao-Bo; Tan, Ning-Hua
	2015-12-30
发表期刊	TETRAHEDRON
卷号	71 期号:52 页码:9673-9678
摘要	Three new cyclic hexapeptides, named as rubicordins A-C (1-3), together with seven known ones (4-10) were isolated from the roots and rhizomes of Rubia cordifolia. Their structures were elucidated by spectroscopic analysis, and the cytotoxic and NF-kappa B signaling pathway activities were tested. The results indicated that 1-10 showed cytotoxicity against SGC-7901, A549 or Hela cancer cell lines, and 1-3 inhibited NF-kappa B signaling pathway. (C) 2015 Elsevier Ltd. All rights reserved.
关键词	Rubia Cordifolia Rubicordins A-c Cyclopeptides Cytotoxicity Nf-kappa b Signaling Pathway
DOI	10.1016/j.tet.2015.10.044
收录类别	SCI
语种	英语
WOS记录号	WOS:000366535800012
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25321
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Chen, Xiao-Qiang,Zhao, Si-Meng,Wang, Zhe,et al. Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway[J]. TETRAHEDRON,2015,71(52):9673-9678.
APA	Chen, Xiao-Qiang,Zhao, Si-Meng,Wang, Zhe,Zeng, Guang-Zhi,Huang, Mao-Bo,&Tan, Ning-Hua.(2015).Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway.TETRAHEDRON,71(52),9673-9678.
MLA	Chen, Xiao-Qiang,et al."Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway".TETRAHEDRON 71.52(2015):9673-9678.

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