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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：183/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
浏览  |  Adobe PDF(4714Kb)  |  收藏  |  浏览/下载：332/43  |  提交时间：2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Identification of novel monoamine oxidase selective inhibitors employing a hierarchical ligand-based virtual screening strategy 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 8, 页码: 801-816
作者:  Wang, Dong;  Li, Zhaoyang;  Liu, Yi;  Chen, Mo;  Chen, Nianhang;  Zuo, Zhili;  Kong, De-Xin
浏览  |  Adobe PDF(1462Kb)  |  收藏  |  浏览/下载：166/33  |  提交时间：2019/09/10
BRS-3D  monoamine oxidase selective inhibitors  virtual screening  
(+)- and (-)-Alternarilactone A: Enantiomers with a Diepoxy-Cage-like Scaffold from an Endophytic Alternaria sp. 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 4, 页码: 735-740
作者:  Tang, Jian-Wei;  Xu, Hou-Chao;  Wang, Wei-Guang;  Hu, Kun;  Zhou, Yuan-Fei;  Chen, Rong;  Li, Xiao-Nian;  Du, Xue;  Sun, Han-Dong;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1213Kb)  |  收藏  |  浏览/下载：291/35  |  提交时间：2019/06/24
Structural Revision of Macropodumine A and Structure of 2-Deoxymacropodumine A, Daphniphyllum Alkaloids with 11-Membered Macrolactone Rings 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 3, 页码: 427-430
作者:  Zhang, Jiahui;  Cao, Pei;  Ma, Yuanliang;  Fang, Xin;  Yang, Jing;  Zhang, Yu;  Chen, Duozhi;  Gu, Yucheng;  Di, Yingtong;  Hao, Xiaojiang
浏览  |  Adobe PDF(1044Kb)  |  收藏  |  浏览/下载：215/70  |  提交时间：2019/07/29
Premnafulvol A: A Diterpenoid with a 6/5/7/3-Fused Tetracyclic Core and Its Biosynthetically Related Analogues from Premna fulva 期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 19, 页码: 6314-6317
作者:  Pu, De-Bing;  Du, Bao-Wen;  Chen, Wen;  Gao, Jun-Bo;  Hu, Kun;  Shi, Nan;  Li, Yi-Ming;  Zhang, Xing-Jie;  Zhang, Rui-Han;  Li, Xiao-Nian;  Zhang, Hong-Bin;  Wang, Fei;  Xiao, Wei-Lie
收藏  |  浏览/下载：181/0  |  提交时间：2018/11/12
Cirsitakaoside isolated from Prenma szemaoensis reduces LPS-induced inflammatory responses in vitro and in vivo 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 59, 页码: 384-390
作者:  Zhu, Huihui;  Pu, Debing;  Di, Qianqian;  Zhao, Xibao;  Ji, Feiyang;  Li, Hongrui;  Zhao, Zizhao;  Gao, Junbo;  Xiao, Weilie;  Chen, Weilin
收藏  |  浏览/下载：93/0  |  提交时间：2018/07/16
Cirsitakaoside  Lps  Inflammation  Macrophage  Nf-kappa b  
Rabdocoestin B exhibits antitumor activity by inducing G2/M phase arrest and apoptosis in esophageal squamous cell carcinoma 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018, 卷号: 81, 期号: 3, 页码: 469-481
作者:  Wang, Jingnan;  Zhang, Zhirong;  Che, Yun;  Yuan, Zuyang;  Lu, Zhiliang;  Li, Yuan;  Wan, Jun;  Sun, Handong;  Chen, Zhaoli;  Pu, Jianxin;  He, Jie
收藏  |  浏览/下载：296/0  |  提交时间：2018/05/08
Rabdocoestin b  G2/m Phase Arrest  Apoptosis  Cytotoxicity  Esophageal Squamous Cell Carcinoma  
SJP-L-5 inhibits HIV-1 polypurine tract primed plus-strand DNA elongation, indicating viral DNA synthesis initiation at multiple sites under drug pressure 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 期号: 1, 页码: 2574
作者:  Zhang, Xing-Jie;  Wang, Rui-Rui;  Chen, Huan;  Luo, Rong-Hua;  Yang, Liu-Meng;  Liu, Jing-Ping;  Sun, Han-Dong;  Zhang, Hong-Bin;  Xiao, Wei-Lie;  Zheng, Yong-Tang
浏览  |  Adobe PDF(2175Kb)  |  收藏  |  浏览/下载：380/27  |  提交时间：2018/05/08
Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 1
作者:  Yuan, Wen-Juan;  Ding, Xiao;  Wang, Zhe;  Yang, Bi-Juan;  Li, Xiao-Nian;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Chen, Quan;  Di, Ying-Tong;  Aisa, Haji Akber;  Hao, Xiao-Jiang
Adobe PDF(3375Kb)  |  收藏  |  浏览/下载：289/54  |  提交时间：2017/12/18