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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:76/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
Authors:  M Song;  D Chen;  S P Yu
Adobe PDF(1390Kb)  |  Favorite  |  View/Download:80/1  |  Submit date:2017/07/24
Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis 期刊论文
PHYTOMEDICINE, 2020
Authors:  Wang Yu-Ling;  Wu Wei;  Su Yong-Nan;  Ai Zhi-Peng;  Mou Han-Chuan;  Wan Luo-Sheng;  Luo Ying;  Qiu Ming-Hua;  Zhang Ji-Hong
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Polyphyllosides A-F, six new spirostanol saponins from the stems and leaves of Paris polyphylla var. chinensis 期刊论文
BIOORGANIC CHEMISTRY, 2020
Authors:  Qin, Xu-Jie;  Zhang, Lan-Jun;  Zhang, Yu;  Ni, Wei;  Yang, Xing-Zhi;  Yu, Qian;  Yan, Huan;  An, Lin-Kun;  Liu, Hai-Yang
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Discovery of isopenicin A, a meroterpenoid as a novel inhibitor of tubulin polymerization 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020
Authors:  Chen, Lin;  Fan, Dong-Mei;  Tang, Jian-Wei;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Puno, Pema-Tenzin;  Li, Yan
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Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
Authors:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
View  |  Adobe PDF(2215Kb)  |  Favorite  |  View/Download:53/12  |  Submit date:2020/03/18
B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells 期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 18, 页码: 3371-3386
Authors:  Zhou, Hongyu;  Yu, Chunlei;  Kong, Lingmei;  Xu, Xiaoliang;  Yan, Juming;  Li, Yingchao;  An, Tao;  Gong, Liang;  Gong, Yaxiao;  Zhu, Huifang;  Zhang, Hongbin;  Yang, Xiaodong;  Li, Yan
View  |  Adobe PDF(5225Kb)  |  Favorite  |  View/Download:127/8  |  Submit date:2019/06/24
RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 14
Authors:  Guo, Di;  Wang, Yurong;  Wang, Jing;  Song, Lihua;  Wang, Zhe;  Mao, Bingyu;  Tan, Ninghua
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RA-XII  lipogenesis  SCAP  SREBP  liver cancer  
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
Authors:  Deng, Guogang;  Zhou, Bei;  Wang, Jing;  Chen, Zhuo;  Gong, Liang;  Gong, Yaxiao;  Wu, Dongmei;  Li, Yan;  Zhang, Hongbin;  Yang, Xiaodong
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Diosgenin  Cholesterol  Dehydroepiandrosterone  Imidazolium salt  Antitumor activities  Structure-activity relationships  
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
Authors:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li;  Fu, Yan-Hui;  Morris-Natschke, Susan L.;  Hamel, Ernest;  Lee, Kuo-Hsiung;  Hao, Xiao-Jiang
View  |  Adobe PDF(3129Kb)  |  Favorite  |  View/Download:57/7  |  Submit date:2019/07/29
aspidosperma-type  monoterpenoid indole alkaloids  antiproliferative activity  tubulin inhibitor  Bousigonia mekongensis