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Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：207/31  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：250/72  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Chloroplast phylogenomic analysis provides insights into the evolution of the largest eukaryotic genome holder, Paris japonica (Melanthiaceae) 期刊论文
BMC PLANT BIOLOGY, 2019, 卷号: 19, 页码: 11
作者:  Yang, Lifang;  Yang, Zhenyan;  Liu, Changkun;  He, Zhengshan;  Zhang, Zhirong;  Yang, Jing;  Liu, Haiyang;  Yang, Junbo;  Ji, Yunheng
Adobe PDF(2680Kb)  |  收藏  |  浏览/下载：342/63  |  提交时间：2019/07/29
Plastome  Phylogenomics  Giant genome  Evolution  Paris japonica  Paris  Trillium govanianum  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(3915Kb)  |  收藏  |  浏览/下载：244/41  |  提交时间：2019/07/29
Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 13
作者:  Guan, Ruowei;  Peng, Yuan;  Zhou, Lutan;  Zheng, Wenqi;  Liu, Xixi;  Wang, Pin;  Yuan, Qingxia;  Gao, Na;  Zhao, Longyan;  Zhao, Jinhua
Adobe PDF(2313Kb)  |  收藏  |  浏览/下载：177/6  |  提交时间：2019/06/24
Apostichopus japonicus  fucosylated glycosaminoglycan  oligosaccharide  unambiguous structure  anti-Fxase  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：179/36  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Statistically correlating NMR spectra and LC-MS data to facilitate the identification of individual metabolites in metabolomics mixtures 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, 卷号: 411, 期号: 7, 页码: 1301-1309
作者:  Li, Xing;  Luo, Huan;  Huang, Tao;  Xu, Li;  Shi, Xiaohuo;  Hu, Kaifeng
Adobe PDF(1588Kb)  |  收藏  |  浏览/下载：201/48  |  提交时间：2019/07/29
Deconvolution  LC-MS  NMR  Statistical correlation  Structure identification  
Response to climate change of montane herbaceous plants in the genus Rhodiola predicted by ecological niche modelling 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 页码: 5879
作者:  You, Jianling;  Qin, Xiaoping;  Ranjitkar, Sailesh;  Lougheed, Stephen C.;  Wang, Mingcheng;  Zhou, Wen;  Ouyang, Dongxin;  Zhou, Yin;  Xu, Jianchu;  Zhang, Wenju;  Wang, Yuguo;  Yang, Ji;  Song, Zhiping
Adobe PDF(3730Kb)  |  收藏  |  浏览/下载：184/40  |  提交时间：2018/05/08
Phylogeography of rare fern Polystichum glaciale endemic to the subnival zone of the Sino-Himalaya 期刊论文
PLANT SYSTEMATICS AND EVOLUTION, 2018, 卷号: 304, 期号: 4, 页码: 485-499
作者:  Luo, Dong;  Xu, Bo;  Rana, Santosh Kumar;  Li, Zhi-Min;  Sun, Hang
Adobe PDF(6093Kb)  |  收藏  |  浏览/下载：197/32  |  提交时间：2018/05/08
Ecological Niche Modelling  Genetic Diversity  Phylogeography  Polystichum Glaciale  Sino-himalaya  Subnival Vegetation  
Enzyme-Assisted Extraction Optimization, Characterization and Antioxidant Activity of Polysaccharides from Sea Cucumber Phyllophorus proteus 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 590
作者:  Qin, Yujing;  Yuan, Qingxia;  Zhang, Yuexing;  Li, Jialu;  Zhu, Xinjiao;  Zhao, Lingling;  Wen, Jing;  Liu, Jikai;  Zhao, Longyan;  Zhao, Jinhua
Adobe PDF(5270Kb)  |  收藏  |  浏览/下载：282/74  |  提交时间：2018/07/02
Sea Cucumber  Polysaccharide  Enzyme-assisted Extraction  Characterization  Antioxidant Activity