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KIB OpenIR
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Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
浏览  |  Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：171/35  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Discovery of new dual binding TNKS inhibitors of Wnt signaling inhibition by pharmacophore modeling, molecular docking and bioassay 期刊论文
MOLECULAR BIOSYSTEMS, 2017, 卷号: 13, 期号: 2, 页码: 363-370
作者:  Pu, Yinglan;  Zhang, Shuqun;  Chang, Zhe;  Zhang, Yunqin;  Wang, Dong;  Zhang, Li;  Li, Yan;  Zuo, Zhili
浏览  |  Adobe PDF(972Kb)  |  收藏  |  浏览/下载：693/120  |  提交时间：2017/05/19
RACK1 is required for adipogenesis 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, 卷号: 311, 期号: 5, 页码: C831-C836
作者:  Kong, Qinghua;  Gao, Lan;  Niu, Yanfen;  Gongpan, Pianchou;  Xu, Yuhui;  Li, Yan;  Xiong, Wenyong
浏览  |  Adobe PDF(1017Kb)  |  收藏  |  浏览/下载：316/48  |  提交时间：2017/02/14
Rack1  3t3-l1  Adipogenesis  Wnt  Pi3k-akt-mtor-s6k  
Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 116, 页码: 39-50
作者:  Zhou, Hongyu;  Shang, Chaowei;  Wang, Min;  Shen, Tao;  Kong, Lingmei;  Yu, Chunlei;  Ye, Zhennan;  Luo, Yan;  Liu, Lei;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(3794Kb)  |  收藏  |  浏览/下载：181/38  |  提交时间：2017/01/05
Ciclopirox  Mtor  Ampk  Tsc2  Raptor  
Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 9, 页码: 10203-10214
作者:  Kong, Ling-Mei;  Feng, Tao;  Wang, Yuan-Yuan;  Li, Xing-Yao;  Ye, Zhen-Nan;  An, Tao;  Qing, Chen;  Luo, Xiao-Dong;  Li, Yan
浏览  |  Adobe PDF(7290Kb)  |  收藏  |  浏览/下载：240/51  |  提交时间：2016/08/22
Bisleuconothine a  Inhibitor  Wnt Signaling  Colorectal Cancer Cells  
Novel beta-carbolines inhibit Wnt/beta-catenin signaling 期刊论文
CELL DEATH & DISEASE, 2015, 卷号: 6, 期号: 11, 页码: e1983
作者:  Kong, LM;  Mao, BY;  Zhu, HJ;  Li, Y.
浏览  |  Adobe PDF(232Kb)  |  收藏  |  浏览/下载：226/65  |  提交时间：2016/02/01
The Ubiquitin Ligase RNF220 Enhances Canonical Wnt Signaling through USP7-Mediated Deubiquitination of beta-Catenin 期刊论文
MOLECULAR AND CELLULAR BIOLOGY, 2014, 卷号: 34, 期号: 23, 页码: 4355-4366
作者:  Ma, Pengcheng;  Yang, Xiangcai;  Kong, Qinghua;  Li, Chaocui;  Yang, Shuangjuan;  Li, Yan;  Mao, Bingyu;  Mao,BY (reprint author),Kunming Inst Zool,State Key Lab Genet Resources & Evolut,Kunming,Peoples R China.;  mao@mail.kiz.ac.cn
浏览  |  Adobe PDF(1708Kb)  |  收藏  |  浏览/下载：282/56  |  提交时间：2015/01/20
Stem-cell Fate  Shoot Apical Meristem  Arabidopsis Shoot  Crabs-claw  Nectary Development  Expression  Thaliana  Family  Loop  Polarity  Iayabby2  Ad-abaxial Polarity  Incarvillea Arguta  Arabidopsis Thaliana  
Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 20, 页码: 10140-10150
作者:  Zhou, Hongyu;  Shen, Tao;  Shang, Chaowei;  Luo, Yan;  Liu, Lei;  Yan, Juming;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(2703Kb)  |  收藏  |  浏览/下载：219/47  |  提交时间：2015/06/17
Ciclopirox  Autophagy  Rhabdomyosarcoma  Reactive Oxygen Species  Jnk  
Mangiferin and its aglycone, norathyriol, improve glucose metabolism by activation of AMP-activated protein kinase 期刊论文
PHARMACEUTICAL BIOLOGY, 2014, 卷号: 52, 期号: 1, 页码: 68-73
作者:  Wang, Fang;  Yan, Juming;  Niu, Yanfen;  Li, Yan;  Lin, Hua;  Liu, Xu;  Liu, Jikai;  Li, Ling
浏览  |  Adobe PDF(383Kb)  |  收藏  |  浏览/下载：290/61  |  提交时间：2014/04/09
Active Metabolite  Ampk  Insulin Resistance  L6 Muscle Cells  Norathyriol  
Bioactive phenolics and terpenoids from Manglietia insignis 期刊论文
FITOTERAPIA, 2013, 卷号: 84, 页码: 58-63
作者:  Shang, Shan-Zhai;  Kong, Ling-Mei;  Yang, Li-Ping;  Jiang, Jing;  Huang, Jin;  Zhang, Hai-Bo;  Shi, Yi-Ming;  Zhao, Wei;  Li, Hong-Lin;  Luo, Huai-Rong;  Li, Yan;  Xiao, Wei-Lie;  Sun, Han-Dong
浏览  |  Adobe PDF(340Kb)  |  收藏  |  浏览/下载：497/128  |  提交时间：2013/07/24
Manglietia Insignis  Magnoliaceae  Neolignan  Sesquiterpene  Bioactivity