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Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：377/42  |  提交时间：2017/12/18
Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 1
作者:  Yuan, Wen-Juan;  Ding, Xiao;  Wang, Zhe;  Yang, Bi-Juan;  Li, Xiao-Nian;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Chen, Quan;  Di, Ying-Tong;  Aisa, Haji Akber;  Hao, Xiao-Jiang
Adobe PDF(3375Kb)  |  收藏  |  浏览/下载：287/53  |  提交时间：2017/12/18
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 11, 页码: UNSP 1934
作者:  Song, Lihua;  Wang, Zhe;  Wang, Yurong;  Guo, Di;  Yang, Jianhong;  Chen, Lijuan;  Tan, Ninghua
Adobe PDF(4110Kb)  |  收藏  |  浏览/下载：150/36  |  提交时间：2018/05/08
Ra-xii  Cyclopeptide  Autophagy  Apoptosis  Mtor  Hepg2 Liver Cancer Cells  
Old drug, new indication: Olsalazine sodium reduced serum uric acid levels in mice via inhibiting xanthine oxidoreductase activity 期刊论文
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2017, 卷号: 135, 期号: 3, 页码: 114-120
作者:  Niu, Yanfen;  Li, Hongjian;  Gao, Lihui;  Lin, Hua;  Kung, Hsiangfu;  Lin, Marie Chia-mi;  Leung, Kwong-Sak;  Wong, Man-Hon;  Xiong, Wenyong;  Li, Ling
收藏  |  浏览/下载：96/0  |  提交时间：2018/05/08
Olsalazine Sodium  Hyperuricemia  Xanthine Oxidase  Uric Acid  
UFLC-MS-IT-TOF and Bioassay Guided Isolation of Flavonoids as Xanthine Oxidase Inhibitors from Diospyros dumetorum 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2017, 卷号: 12, 期号: 11, 页码: 1713-1715
作者:  Deng, Zhen-Tao;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Chen, Xing-Long;  Zhang, Jian-Gang;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
Adobe PDF(406Kb)  |  收藏  |  浏览/下载：274/80  |  提交时间：2018/05/08
Diospyros Dumetorum  Uflc-ms-it-tof  Bioassay-guided Isolation  Xod Inhibitory Activity  Flavonoids  
Bioactive ent-kaurane diterpenoids from Isodon rubescens 期刊论文
PHYTOCHEMISTRY, 2017, 卷号: 143, 页码: 199-207
作者:  Zhang, Yuan-Yuan;  Jiang, Hua-Yi;  Liu, Miao;  Hu, Kun;  Wang, Wei-Guang;  Du, Xue;  Li, Xiao-Nian;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(1170Kb)  |  收藏  |  浏览/下载：416/63  |  提交时间：2017/11/20
Isodon Rubescens  Lamiaceae  Cytotoxicity  7  Anti-inflammatory  20-epoxy-ent-kaurane Diterpenoids  
Metabolic profiling of dehydrodiisoeugenol using xenobiotic metabolomics 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2017, 卷号: 145, 页码: 725-733
作者:  Lv, Qian-Qian;  Yang, Xiao-Nan;  Yan, Dong-Mei;  Liang, Wei-Qing;  Liu, Hong-Ning;  Yang, Xiu-Wei;  Li, Fei
Adobe PDF(744Kb)  |  收藏  |  浏览/下载：328/73  |  提交时间：2017/10/23
Dehydrodiisoeugenol  Xenobiotic Metabolomics  Metabolic Profiling  Uplc-esi-qtofms  
Structural Elucidation and Biological Activity of a Highly Regular Fucosylated Glycosaminoglycan from the Edible Sea Cucumber Stichopus herrmanni 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017, 卷号: 65, 期号: 42, 页码: 9315-9323
作者:  Li, Xiaomei;  Luo, Lan;  Cai, Ying;  Yang, Wenjiao;  Lin, Lisha;  Li, Zi;  Gao, Na;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
Adobe PDF(1246Kb)  |  收藏  |  浏览/下载：329/126  |  提交时间：2017/12/18
Sea Cucumber  Fucosylated Glycosaminoglycan  Chemical Structure  Anticoagulant  Stiehopus Herrmanni  
Novel monoterpenoid indole alkaloids from Melodinus yunnanensis 期刊论文
TETRAHEDRON, 2017, 卷号: 73, 期号: 40, 页码: 5821-5826
作者:  Zhang, Bing-Jie;  Liu, Cheng;  Bao, Mei-Fen;  Zhong, Xiu-Hong;  Ni, Ling;  Wu, Jing;  Cai, Xiang-Hai
Adobe PDF(553Kb)  |  收藏  |  浏览/下载：315/68  |  提交时间：2017/10/23
Melodinus Yunnanensis  Apocynaceae  Monoterpenoid Indole Alkaloids  Structure Elucidation  
Virtual screening of B-Raf kinase inhibitors: A combination of pharmacophore modelling, molecular docking, 3D-QSAR model and binding free energy calculation studies 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2017, 卷号: 70, 页码: 186-190
作者:  Zhang, Wen;  Qiu, Kai-Xiong;  Yu, Fang;  Xie, Xiao-Guang;  Zhang, Shu-Qun;  Chen, Ya-Juan;  Xie, Hui-Ding
Adobe PDF(371Kb)  |  收藏  |  浏览/下载：139/23  |  提交时间：2017/12/11
B-raf Kinase Inhibitors  Virtual Screening  Pharmacophore  Molecular Docking  3d Qsar  Binding Free Energy Calculation