Novel monoterpenoid indole alkaloids from Melodinus yunnanensis
Zhang, Bing-Jie1,2; Liu, Cheng3; Bao, Mei-Fen1; Zhong, Xiu-Hong1; Ni, Ling1,2; Wu, Jing1,2; Cai, Xiang-Hai1
2017-10-05
发表期刊TETRAHEDRON
ISSN0040-4020
卷号73期号:40页码:5821-5826
摘要Five monoterpenoid indole alkaloids, namely meloyines A-B (1-2), meloyines II-III (3-4), and 10-O-glucosyl-scandine (5) together with thirty-four known alkaloids were isolated from leaves and twigs of Melodinus yunnanensis. Alkaloid 1 was characterized as an unprecedented skeleton with a 6/5/5/6/6/4 ring system, and alkaloids 3-4 were dimeric monoterpenoid quinolone alkaloids. Their structures were elucidated based on 1D and 2D- NMR, FTIR, UV, and MS spectroscopic data. The cytotoxic activity of new alkaloids were evaluated against three human cancer cell lines. (C) 2017 Elsevier Ltd. All rights reserved.
关键词Melodinus Yunnanensis Apocynaceae Monoterpenoid Indole Alkaloids Structure Elucidation
学科领域Chemistry, Organic
DOI10.1016/j.tet.2017.08.008
收录类别SCI
语种英语
WOS记录号WOS:000412036700001
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/54873
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Southwest China Germplasm Bank Wild Species, Kunming 650201, Yunnan, Peoples R China
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Zhang, Bing-Jie,Liu, Cheng,Bao, Mei-Fen,et al. Novel monoterpenoid indole alkaloids from Melodinus yunnanensis[J]. TETRAHEDRON,2017,73(40):5821-5826.
APA Zhang, Bing-Jie.,Liu, Cheng.,Bao, Mei-Fen.,Zhong, Xiu-Hong.,Ni, Ling.,...&Cai, Xiang-Hai.(2017).Novel monoterpenoid indole alkaloids from Melodinus yunnanensis.TETRAHEDRON,73(40),5821-5826.
MLA Zhang, Bing-Jie,et al."Novel monoterpenoid indole alkaloids from Melodinus yunnanensis".TETRAHEDRON 73.40(2017):5821-5826.
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