Novel monoterpenoid indole alkaloids from Melodinus yunnanensis | |
Zhang, Bing-Jie1,2; Liu, Cheng3; Bao, Mei-Fen1; Zhong, Xiu-Hong1; Ni, Ling1,2; Wu, Jing1,2; Cai, Xiang-Hai1 | |
2017-10-05 | |
发表期刊 | TETRAHEDRON |
ISSN | 0040-4020 |
卷号 | 73期号:40页码:5821-5826 |
摘要 | Five monoterpenoid indole alkaloids, namely meloyines A-B (1-2), meloyines II-III (3-4), and 10-O-glucosyl-scandine (5) together with thirty-four known alkaloids were isolated from leaves and twigs of Melodinus yunnanensis. Alkaloid 1 was characterized as an unprecedented skeleton with a 6/5/5/6/6/4 ring system, and alkaloids 3-4 were dimeric monoterpenoid quinolone alkaloids. Their structures were elucidated based on 1D and 2D- NMR, FTIR, UV, and MS spectroscopic data. The cytotoxic activity of new alkaloids were evaluated against three human cancer cell lines. (C) 2017 Elsevier Ltd. All rights reserved. |
关键词 | Melodinus Yunnanensis Apocynaceae Monoterpenoid Indole Alkaloids Structure Elucidation |
学科领域 | Chemistry, Organic |
DOI | 10.1016/j.tet.2017.08.008 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000412036700001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/54873 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Southwest China Germplasm Bank Wild Species, Kunming 650201, Yunnan, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Bing-Jie,Liu, Cheng,Bao, Mei-Fen,et al. Novel monoterpenoid indole alkaloids from Melodinus yunnanensis[J]. TETRAHEDRON,2017,73(40):5821-5826. |
APA | Zhang, Bing-Jie.,Liu, Cheng.,Bao, Mei-Fen.,Zhong, Xiu-Hong.,Ni, Ling.,...&Cai, Xiang-Hai.(2017).Novel monoterpenoid indole alkaloids from Melodinus yunnanensis.TETRAHEDRON,73(40),5821-5826. |
MLA | Zhang, Bing-Jie,et al."Novel monoterpenoid indole alkaloids from Melodinus yunnanensis".TETRAHEDRON 73.40(2017):5821-5826. |
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