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Metabolic profiling of tyrosine kinase inhibitor nintedanib using metabolomics 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020
Authors:  Zhou, Zi-Meng;  Wang, Yi-Kun;  Yan, Dong-Mei;  Fang, Jian-He;  Xiao, Xue-Rong;  Zhang, Ting;  Cheng, Yan;  Xu, Kang-Ping;  Li, Fei
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Metabolic profiling of coumarins by the combination of UPLC-MS-based metabolomics and multiple mass defect filter 期刊论文
XENOBIOTICA, 2020
Authors:  Xiao, Yao;  Wang, Yi-Kun;  Xiao, Xue-Rong;  Zhao, Qi;  Huang, Jian-Feng;  Zhu, Wei-Feng;  Li, Fei
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The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
Authors:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(1740Kb)  |  Favorite  |  View/Download:12/0  |  Submit date:2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(3136Kb)  |  Favorite  |  View/Download:30/10  |  Submit date:2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
Authors:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
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A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(1101Kb)  |  Favorite  |  View/Download:54/7  |  Submit date:2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
Authors:  Zhu, Xu;  Wang, Yi-Kun;  Yang, Xiao-Nan;  Xiao, Xue-Rong;  Zhang, Ting;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Li, Fei
Adobe PDF(4316Kb)  |  Favorite  |  View/Download:85/5  |  Submit date:2019/05/24
myristicin  1 '-hydroxymyristicin  metabolic activation  metabolomics  
PPAR alpha Mediates the Hepatoprotective Effects of Nutmeg 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 5, 页码: 1887-1897
Authors:  Yang, Xiao-Nan;  Liu, Xue-Mei;  Fang, Jian-He;  Zhu, Xu;  Yang, Xiu-Wei;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(2643Kb)  |  Favorite  |  View/Download:125/20  |  Submit date:2018/07/02
Nutmeg  Hepatoprotective Activity  Metabolomics  Myrislignan  Ppar Alpha  
胆汁淤积性肝损伤的代谢组学研究 学位论文
硕士, 2018
Authors:  杨锐
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Metabolic map of osthole and its effect on lipids 期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 3, 页码: 285-299
Authors:  Zhao, Qi;  Li, Xin-Mei;  Liu, Hong-Ning;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(2482Kb)  |  Favorite  |  View/Download:159/32  |  Submit date:2017/11/17
Lipid  Metabolomics  Metabolic Disease  Osthole  Time-of-flight Mass Spectrometry  Ultra-performance Liquid Chromatography