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The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载:80/1  |  提交时间:2017/07/24
The compound BTB06584 is an IF1-dependent selective inhibitor of the mitochondrial F1Fo-ATPase1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-38
作者:  Fabrice Ivanes;  Danilo Faccenda;  Jemma Gatliff;  Ahmed A Ahmed;  Stefania Cocco;  Carol Ho Ka Cheng;  Emma Allan;  Claire Russell;  Michael R Duchen;  Michelangelo Campanella
Adobe PDF(1228Kb)  |  收藏  |  浏览/下载:1/1  |  提交时间:2017/07/24
Mitochondrial F1fo Atp Synthase  If1  Ischemia-induced Death  Btb06584  Pinotage  
Anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal through inhibition of STAT3 pathway 期刊论文
出版物, 3111, 期号: 0, 页码: 1-50
作者:  Jung Ok Ban;  Dae Hwan Kim;  Hee Pom Lee;  Chul Ju Hwang;  Jung-Hyun Shim;  Dae Joong Kim;  Tae Myoung Kim;  Heon Sang Jeong;  Seong Su Nah;  Hanyong Chen;  Zigang Dong;  Young Wan Ham;  Youngsoo Kim;  Sang-Bae Han;  Jin Tae Hong
Adobe PDF(1327Kb)  |  收藏  |  浏览/下载:2/1  |  提交时间:2017/07/24
Natural Breviscapin, Mangiferin, and a Modified Mangostin Present Inhibitory Effect on Dipeptidyl Peptidase-IV 期刊论文
CHEMISTRYSELECT, 2018, 卷号: 3, 期号: 39, 页码: 10864-10868
作者:  Hou, Bo;  Kuang, Meng-Ting;  Chi, Xiao-Qian;  Li, Jin-Yu;  Yang, Liu;  Liu, Zhen-Hua;  Yuan, Ming-Yan;  Kong, Qing-Hua;  Hu, Jiang-Miao;  Zhou, Jun
收藏  |  浏览/下载:61/0  |  提交时间:2018/12/03
DPP-IV inhibitors  Scutellaria baicalensis  Mango  Natural products  Virtual Screening  
Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60
作者:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying;  Liu, Xingyong;  Siddique, Abu Nasar;  Zhang, Li;  Zuo, Zhili
收藏  |  浏览/下载:1/0  |  提交时间:2018/11/12
Checkpoint kinase 1 inhibitor  Virtual screening  Pharmacophore modeling  Molecular docking  Molecular dynamics simulations  
Discovery of novel wee1 inhibitors via structure-based virtual screening and biological evaluation 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2018, 卷号: 32, 期号: 9, 页码: 901-915
作者:  Li, Yaping;  Pu, Yinglan;  Liu, Hui;  Zhang, Li;  Liu, Xingyong;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载:61/0  |  提交时间:2018/11/06
Wee1 inhibitors  Pharmacophore model  Molecular docking  Virtual screening  Molecular dynamics simulation  
Ecological and Genetic Divergences with Gene Flow of Two Sister Species (&ITLeucomeris decora&IT and &ITNouelia insignis&IT) Driving by Climatic Transition in Southwest China 期刊论文
FRONTIERS IN PLANT SCIENCE, 2018, 卷号: 9, 页码: 31
作者:  Zhao, Yujuan;  Yin, Genshen;  Pan, Yuezhi;  Gong, Xun
Adobe PDF(2640Kb)  |  收藏  |  浏览/下载:13/1  |  提交时间:2018/05/08
Climatic Shift  Coalescent Analyses  Endemic Species  Gene Flow  Niche Differentiation  Speciation  
Domestication Origin and Breeding History of the Tea Plant (Camellia sinensis) in China and India Based on Nuclear Microsatellites and cpDNA Sequence Data 期刊论文
FRONTIERS IN PLANT SCIENCE, 2018, 卷号: 8, 期号: 1, 页码: 2270
作者:  Meegahakumbura, Muditha K.;  Wambulwa, Moses C.;  Li, Miao-Miao;  Thapa, Kishore K.;  Sun, Yong-Shuai;  Moller, Michael;  Xu, Jian-Chu;  Yang, Jun-Bo;  Liu, Jie;  Liu, Ben-Ying;  Li, De-Zhu;  Gao, Lian-Ming
Adobe PDF(2640Kb)  |  收藏  |  浏览/下载:46/1  |  提交时间:2018/05/08
Camellia Sinensis  Nssr  Cpdna Sequence  Domestication Center  Breeding History  
Manginoids A-G: Seven Monoterpene-Shikimate-Conjugated Meroterpenoids with a Spiro Ring System from Guignardia mangiferae 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 21, 页码: 5956-5959
作者:  Chen, Keliang;  Zhang, Xuwen;  Sun, Weiguang;  Liu, Junjun;  Yang, Jing;  Chen, Chunmei;  Liu, Xiulan;  Gao, Limin;  Wang, Jianping;  Li, Hua;  Luo, Zengwei;  Xue, Yongbo;  Zhu, Hucheng;  Zhang, Yonghui
Adobe PDF(1771Kb)  |  收藏  |  浏览/下载:115/0  |  提交时间:2017/12/18
Old drug, new indication: Olsalazine sodium reduced serum uric acid levels in mice via inhibiting xanthine oxidoreductase activity 期刊论文
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2017, 卷号: 135, 期号: 3, 页码: 114-120
作者:  Niu, Yanfen;  Li, Hongjian;  Gao, Lihui;  Lin, Hua;  Kung, Hsiangfu;  Lin, Marie Chia-mi;  Leung, Kwong-Sak;  Wong, Man-Hon;  Xiong, Wenyong;  Li, Ling
收藏  |  浏览/下载:11/0  |  提交时间:2018/05/08
Olsalazine Sodium  Hyperuricemia  Xanthine Oxidase  Uric Acid