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Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：391/43  |  提交时间：2017/12/18
Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 1
作者:  Yuan, Wen-Juan;  Ding, Xiao;  Wang, Zhe;  Yang, Bi-Juan;  Li, Xiao-Nian;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Chen, Quan;  Di, Ying-Tong;  Aisa, Haji Akber;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3375Kb)  |  收藏  |  浏览/下载：294/56  |  提交时间：2017/12/18
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 11, 页码: UNSP 1934
作者:  Song, Lihua;  Wang, Zhe;  Wang, Yurong;  Guo, Di;  Yang, Jianhong;  Chen, Lijuan;  Tan, Ninghua
浏览  |  Adobe PDF(4110Kb)  |  收藏  |  浏览/下载：158/37  |  提交时间：2018/05/08
Ra-xii  Cyclopeptide  Autophagy  Apoptosis  Mtor  Hepg2 Liver Cancer Cells  
UFLC-MS-IT-TOF and Bioassay Guided Isolation of Flavonoids as Xanthine Oxidase Inhibitors from Diospyros dumetorum 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2017, 卷号: 12, 期号: 11, 页码: 1713-1715
作者:  Deng, Zhen-Tao;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Chen, Xing-Long;  Zhang, Jian-Gang;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(406Kb)  |  收藏  |  浏览/下载：285/84  |  提交时间：2018/05/08
Diospyros Dumetorum  Uflc-ms-it-tof  Bioassay-guided Isolation  Xod Inhibitory Activity  Flavonoids  
New neo-clerodane diterpenoids with neurotrophic activity from the aerial parts of Salvia tiliifolia 期刊论文
FITOTERAPIA, 2017, 卷号: 123, 页码: 44-50
作者:  Fan, Min;  Bao, Ying;  Zhang, Zhi-Jun;  Zhang, Hong-Bin;  Zhao, Qin-Shi
浏览  |  Adobe PDF(515Kb)  |  收藏  |  浏览/下载：166/64  |  提交时间：2018/05/08
Salvia Tiliifolia  Neo-clerodane Diterpenoids  Neurotrophic Activities  Cytotoxicity  
Bioactive ent-kaurane diterpenoids from Isodon rubescens 期刊论文
PHYTOCHEMISTRY, 2017, 卷号: 143, 页码: 199-207
作者:  Zhang, Yuan-Yuan;  Jiang, Hua-Yi;  Liu, Miao;  Hu, Kun;  Wang, Wei-Guang;  Du, Xue;  Li, Xiao-Nian;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(1170Kb)  |  收藏  |  浏览/下载：432/71  |  提交时间：2017/11/20
Isodon Rubescens  Lamiaceae  Cytotoxicity  7  Anti-inflammatory  20-epoxy-ent-kaurane Diterpenoids  
Structural Elucidation and Biological Activity of a Highly Regular Fucosylated Glycosaminoglycan from the Edible Sea Cucumber Stichopus herrmanni 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017, 卷号: 65, 期号: 42, 页码: 9315-9323
作者:  Li, Xiaomei;  Luo, Lan;  Cai, Ying;  Yang, Wenjiao;  Lin, Lisha;  Li, Zi;  Gao, Na;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(1246Kb)  |  收藏  |  浏览/下载：341/132  |  提交时间：2017/12/18
Sea Cucumber  Fucosylated Glycosaminoglycan  Chemical Structure  Anticoagulant  Stiehopus Herrmanni  
Virtual screening of B-Raf kinase inhibitors: A combination of pharmacophore modelling, molecular docking, 3D-QSAR model and binding free energy calculation studies 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2017, 卷号: 70, 页码: 186-190
作者:  Zhang, Wen;  Qiu, Kai-Xiong;  Yu, Fang;  Xie, Xiao-Guang;  Zhang, Shu-Qun;  Chen, Ya-Juan;  Xie, Hui-Ding
浏览  |  Adobe PDF(371Kb)  |  收藏  |  浏览/下载：150/26  |  提交时间：2017/12/11
B-raf Kinase Inhibitors  Virtual Screening  Pharmacophore  Molecular Docking  3d Qsar  Binding Free Energy Calculation  
Potential role of CYP1B1 in the development and treatment of metabolic diseases 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2017, 卷号: 178, 页码: 18-30
作者:  Li, Fei;  Zhu, Weifeng;  Gonzalez, Frank J.
浏览  |  Adobe PDF(2083Kb)  |  收藏  |  浏览/下载：187/61  |  提交时间：2017/11/20
Cyp1b1  Metabolic Diseases  Metabolic Pathways  Metabolomics  
New Bioactive Macrocyclic Diterpenoids from Euphorbia helioscopia 期刊论文
CHEMISTRY & BIODIVERSITY, 2017, 卷号: 14, 期号: 10, 页码: 1
作者:  Hua, Juan;  Luo, Shi-Hong;  Liu, Yan;  Liu, Yan-Chun;  Tan, Yan-Yun;  Feng, Ling;  Xiao, Chao-Jiang;  Zhang, Ke-Qin;  Li, Sheng-Hong;  Niu, Xue-Mei
浏览  |  Adobe PDF(544Kb)  |  收藏  |  浏览/下载：302/89  |  提交时间：2017/11/17
Euphorbia Helioscopia  Euphoscopoids a -c  Diterpenoids  Antifeedant Activities  Cytotoxic Activities.