| New neo-clerodane diterpenoids with neurotrophic activity from the aerial parts of Salvia tiliifolia | |
Fan, Min1,2,3 ; Bao, Ying1,2,3; Zhang, Zhi-Jun2,3; Zhang, Hong-Bin1; Zhao, Qin-Shi2
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| 2017-11-01 | |
| Source Publication | FITOTERAPIA
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| ISSN | 0367-326X |
| Volume | 123Pages:44-50 |
| Abstract | Five new neo-clerodane diterpenoids, tiliifolins A-E (1-5), along with ten known ones, were isolated from the aerial part of Salvia tiliifolia. Their structures were proposed based on 1D and 2D NMR spectroscopic data analysis. All new compounds were evaluated for their neurotrophic activity on PC12 cells and cytotoxicity against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW480), and compound 5 showed statistically significant neuroprotective effect in vitro assay. |
| Keyword | Salvia Tiliifolia Neo-clerodane Diterpenoids Neurotrophic Activities Cytotoxicity |
| DOI | 10.1016/j.fitote.2017.09.013 |
| Language | 英语 |
| WOS ID | WOS:000417963500008 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/60608 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resources, Kunming 650091, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Fan, Min,Bao, Ying,Zhang, Zhi-Jun,et al. New neo-clerodane diterpenoids with neurotrophic activity from the aerial parts of Salvia tiliifolia[J]. FITOTERAPIA,2017,123:44-50. |
| APA | Fan, Min,Bao, Ying,Zhang, Zhi-Jun,Zhang, Hong-Bin,&Zhao, Qin-Shi.(2017).New neo-clerodane diterpenoids with neurotrophic activity from the aerial parts of Salvia tiliifolia.FITOTERAPIA,123,44-50. |
| MLA | Fan, Min,et al."New neo-clerodane diterpenoids with neurotrophic activity from the aerial parts of Salvia tiliifolia".FITOTERAPIA 123(2017):44-50. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| fan2017.pdf（515KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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