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Diversity-oriented one-pot multicomponent synthesis of spirooxindole derivatives and their biological evaluation for anticancer activities 期刊论文
TETRAHEDRON, 2016, 卷号: 72, 期号: 52, 页码: 8523-8536
作者:  Yang, Jun;  Liu, Xiong-Wei;  Wang, Dan-Dan;  Tian, Min-Yi;  Han, Shuo-Nan;  Feng, Ting-Ting;  Liu, Xiong-Li;  Mei, Ren-Qiang;  Zhou, Ying
Adobe PDF(2552Kb)  |  收藏  |  浏览/下载：548/54  |  提交时间：2017/02/14
Five-membered Carbocyclic Spirooxindoles  One-pot Multicomponent Synthesis  Knoevenagel Condensation/michael/cyclization  Aminomethylation  Antitumor Activity  
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
Adobe PDF(13632Kb)  |  收藏  |  浏览/下载：295/33  |  提交时间：2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Two key biogenetic intermediates of Cephalotaxus alkaloids from Cephalotaxus oliveri and C. lanceolata 期刊论文
TETRAHEDRON LETTERS, 2016, 卷号: 57, 期号: 47, 页码: 5201-5204
作者:  Ni, Ling;  Schinnerl, Johann;  Bao, Mei-fen;  Zhang, Bing-jie;  Wu, Jing;  Cai, Xiang-hai
Adobe PDF(953Kb)  |  收藏  |  浏览/下载：226/52  |  提交时间：2017/01/05
Cephalotaxus Oliveri  Cephalotaxus Lanceolata  (+/-)-cephaloliverine a  Cephalolancine a  Biogenetic Intermediates  
CDDO-Me reveals USP7 as a novel target in ovarian cancer cells 期刊论文
Oncotarget, 2016, 卷号: 7, 期号: 47, 页码: 77096-77109
作者:  Qin, Dongjun;  Wang, Weiwei;  Lei, Hu;  Luo, Hao;  Cai, Haiyan;  Tang, Caixia;  Wu, Yunzhao;  Wang, Yingying;  Jin, Jin;  Xiao, Weilie;  Wang, Tongdan;  Ma, Chunmin;  Xu, Hanzhang;  Zhang, Jinfu;  Gao, Fenghou;  Wu, Ying-Li
Adobe PDF(8973Kb)  |  收藏  |  浏览/下载：181/67  |  提交时间：2017/02/14
Cddo-me  Ovarian Cancer  Usp7  Cetsa  Deubiquitinating Enzymes  
New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: 1, 页码: 1
作者:  Yue, Grace Gar-Lee;  Xie, Sida;  Lee, Julia Kin-Ming;  Kwok, Hin-Fai;  Gao, Si;  Nian, Yin;  Wu, Xiao-Xiao;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
Adobe PDF(2501Kb)  |  收藏  |  浏览/下载：261/49  |  提交时间：2016/12/21
Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 66689-66699
作者:  Zhang, Ruowen;  Che, Xun;  Zhang, Jingjie;  Li, Yang;  Li, Jingxia;  Deng, Xu;  Zhu, Junlan;  Jin, Honglei;  Zhao, Qinshi;  Huang, Chuanshu
Adobe PDF(9106Kb)  |  收藏  |  浏览/下载：199/45  |  提交时间：2017/01/05
Chel a  Human Bladder Cancer  Apoptosis  Phlpp2  C-jun  
Compounds from Polyphaga plancyi and their inhibitory activities against JAK3 and DDR1 kinases 期刊论文
FITOTERAPIA, 2016, 卷号: 114, 页码: 163-167
作者:  Zhu, Hong-Jie;  Yan, Yong-Ming;  Tu, Zheng-Chao;  Luo, Jin-Feng;  Liang, Rui;  Yang, Tong-Hua;  Cheng, Yong-Xian;  Wang, Shu-Mei
Adobe PDF(448Kb)  |  收藏  |  浏览/下载：223/69  |  提交时间：2017/01/05
Polyphaga Plancyi Bolivar  Insect  Computational Methods  Jak3  Ddr1  
Bioactive ent-kaurane diterpenoids from Isodon serra 期刊论文
PHYTOCHEMISTRY, 2016, 卷号: 130, 页码: 244-251
作者:  Wan, Jun;  Liu, Miao;  Jiang, Hua-Yi;  Yang, Jin;  Du, Xue;  Li, Xiao-Nian;  Wang, Wei-Guang;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(653Kb)  |  收藏  |  浏览/下载：462/79  |  提交时间：2016/11/04
Isodon Serra  Lamiaceae  Cytotoxic Activity  7  Anti-inflammatory  20-epoxy-ent-kaurane Diterpenoids  
Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 116, 页码: 39-50
作者:  Zhou, Hongyu;  Shang, Chaowei;  Wang, Min;  Shen, Tao;  Kong, Lingmei;  Yu, Chunlei;  Ye, Zhennan;  Luo, Yan;  Liu, Lei;  Li, Yan;  Huang, Shile
Adobe PDF(3794Kb)  |  收藏  |  浏览/下载：178/37  |  提交时间：2017/01/05
Ciclopirox  Mtor  Ampk  Tsc2  Raptor  
Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 37, 页码: 58995-59005
作者:  Wu, Jingjing;  Lei, Hu;  Zhang, Jinfu;  Chen, Xiangyun;  Tang, Caixia;  Wang, Weiwei;  Xu, Hanzhang;  Xiao, Weilie;  Gu, Wenli;  Wu, Yingli
Adobe PDF(2389Kb)  |  收藏  |  浏览/下载：138/32  |  提交时间：2017/01/05
Momordin Ic  Senp1  Sumoylation  Proliferation  Prostate Cancer