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The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
作者:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
收藏  |  浏览/下载:65/0  |  提交时间:2022/04/02
Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Bioactivity Ingredients of Chaenomeles speciosa against Microbes: Characterization by LC-MS and Activity Evaluation 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 16, 页码: 4686-4696
作者:  Wang,Zhao-Jie;  Jin,Dan-Ni;  Zhou,Ying;  Sang,Xu-Yan;  Zhu,Yan-Yan;  He,Ying-Jie;  Xie,Tian-Zhen;  Dai,Zhi;  Zhao,Yun-Li;  Luo,Xiao-Dong
收藏  |  浏览/下载:76/0  |  提交时间:2022/04/02
antimicrobial  Chaenomeles speciosa  LC-MS  metabolomics  LUNG INFLAMMATION  ANTIOXIDANT  FRUITS  POLYSACCHARIDE  
Development of a LC-HRMS based approach to boost structural annotation of isomeric citrus flavanones 期刊论文
PHYTOCHEMICAL ANALYSIS, 2021, 卷号: 32, 期号: 5, 页码: 749-756
作者:  He,Ying-Jie;  Zhou,Ying;  Qin,Yan;  Zhou,Zhong-Shun;  Zhu,Meng;  Zhu,Yan-Yan;  Wang,Zhao-Jie;  Xie,Tian-Zhen;  Zhao,Li-Xing;  Luo,Xiao-Dong
收藏  |  浏览/下载:79/0  |  提交时间:2022/04/02
citrus flavanones  collision energy  fragmentation pattern  high‐  resolution mass spectrometry  ion ratio  RESOLUTION MASS-SPECTROMETRY  HESPERETIN ENANTIOMERS  QUANTIFICATION  NARINGENIN  
Migration of (non-) intentionally added substances and microplastics from microwavable plastic food containers 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 417, 页码: 126074
作者:  He,Ying-Jie;  Qin,Yan;  Zhang,Tie-Li;  Zhu,Yan-Yan;  Wang,Zhao-Jie;  Zhou,Zhong-Shun;  Xie,Tian-Zhen;  Luo,Xiao-Dong
收藏  |  浏览/下载:55/0  |  提交时间:2022/04/02
(Non-) intentionally added substances  Microplastics  High resolution mass spectrometry  Scanning electron microscopy  BISPHENOL-A  POLYPROPYLENE  DEGRADATION  METABOLISM  MICROBIOTA  PARTICLES  SIMULANTS  WATER  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
Adobe PDF(2120Kb)  |  收藏  |  浏览/下载:162/45  |  提交时间:2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Antioxidant and Cytoprotective Effects of New Diarylheptanoids from Rhynchanthus beesianus 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 22, 页码: 6229-6239
作者:  Zhu,Pei-Feng;  Cheng,Gui-Guang;  Zhao,Lan-Qin;  Khan,Afsar;  Yang,Xing-Wei;  Zhang,Bu-Yun;  Li,Meng-Cheng;  Liu,Ya-Ping;  Luo,Xiao-Dong
Adobe PDF(2113Kb)  |  收藏  |  浏览/下载:98/31  |  提交时间:2022/04/02
Rhynchanthus beesianus  diarylheptanoid  antioxidant activity  intracellular reactive oxygen species  cell apoptosis  GINGER ZINGIBER-OFFICINALE  PC12 CELLS  RHIZOMES  NEUROPROTECTION  ACTIVATION  ENZYMES  L.  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
Adobe PDF(2630Kb)  |  收藏  |  浏览/下载:152/82  |  提交时间:2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 11, 页码: 4158-4162
作者:  Hu,Bin-Yuan;  Zhao,Yun-Li;  Xiong,Deng-Sen;  He,Ying-Jie;  Zhou,Zhong-Shun;  Zhu,Pei-Feng;  Wang,Zhao-Jie;  Wang,Yong-Liang;  Zhao,Li-Xing;  Luo,Xiao-Dong
Adobe PDF(1568Kb)  |  收藏  |  浏览/下载:71/19  |  提交时间:2022/04/02
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