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Ten new nortriterpenes from Euphorbia resinifera and their anti-tomato yellow leaf curl virus activities 期刊论文
FITOTERAPIA, 2021, 卷号: 153, 页码: 104989
作者:  Zhao,Ning-Dong;  Li,Yu-Lin;  Song,Yu;  Yang,Bao-Jia;  Ding,Xiao;  Gao,Fang;  Ye,Jian;  Hao,Xiao-Jiang;  Zhang,Yu;  Li,Shun-Lin
Adobe PDF(799Kb)  |  收藏  |  浏览/下载：84/33  |  提交时间：2022/04/02
Euphorbia resinifera  Nortriterpenes  Anti-TYLCV  POLYFUNCTIONAL DITERPENES  TRITERPENOIDS  IRRITANT  ESTERS  RESISTANCE  EUPHANE  LATEX  
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：270/46  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
作者:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
收藏  |  浏览/下载：356/0  |  提交时间：2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization  
Identification of Ingol and Rhamnofolane Diterpenoids from Euphorbia resinifera and Their Abilities to Induce Lysosomal Biosynthesis 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 5, 页码: 1209-1218
作者:  Zhao, Ning-Dong;  Ding, Xiao;  Song, Yu;  Yang, Dong-Qiong;  Adelakun, Tiwalade Adegoke;  Qian, Wen-Dan;  Zhang, Yu;  Di, Ying-Tong;  Gao, Fang;  Hao, Xiao-Jiang;  Li, Shun-Lin
收藏  |  浏览/下载：441/0  |  提交时间：2018/07/16
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
作者:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
收藏  |  浏览/下载：402/0  |  提交时间：2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Efficient synthesis of new phenanthridine Wnt/b-catenin signaling pathway agonists 期刊论文
European Journal of Medicinal Chemistry, 2018, 卷号: 157, 页码: 1491-1499
作者:  Duozhi Chen;  Heng Zhang;  Chenxu Jing;  Xiaoli He;  Bijuan Yang;  Jieyun Cai;  Yunfu Zhou;  Xiaoming Song;  Lin Li;  Xiaojiang Hao
浏览  |  Adobe PDF(1966Kb)  |  收藏  |  浏览/下载：197/78  |  提交时间：2019/03/27
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
作者:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(3775Kb)  |  收藏  |  浏览/下载：131/34  |  提交时间：2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
巨大戟醇及其衍生物在增强溶酶体生成中的应用 专利
申请日期: 2016-03-28, 公开日期: 2017-05-10
发明人:  杨崇林;  郝小江;  李洋;  徐猛;  丁骁;  晏晨;  邸迎彤;  穆淑珍;  蹇友理;  宋智琴;  郭伟翔
收藏  |  浏览/下载：119/0  |  提交时间：2018/05/10
Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction 期刊论文
NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82
作者:  Wang, Sheng;  Yin, Junlin;  Chen, Duozhi;  Nie, Fen;  Song, Xiaomin;  Fei, Cong;  Miao, Haofei;  Jing, Changbin;  Ma, Wenjing;  Wang, Lei;  Xie, Sichun;  Li, Chen;  Zeng, Rong;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(1157Kb)  |  收藏  |  浏览/下载：602/119  |  提交时间：2013/10/16
Glycogen-synthase Kinase-3  Beta-catenin  Negative Regulator  Dix Domain  Stem-cells  In-vivo  Axin  Activation  Pathway  Phosphorylation  
影响经典Wnt信号途径的药物的筛选方法及其应用 专利
专利类型: 发明, 专利号: CN201310074003.5, 申请日期: 2013-03-07, 公开日期: 2014-09-10
发明人:  李林;  汪胜;  郝小江;  宋晓敏;  尹俊林;  陈铎之
Adobe PDF(1252Kb)  |  收藏  |  浏览/下载：152/9  |  提交时间：2016/12/19