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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：182/39  |  提交时间：2020/03/26
Rapid discovery and functional characterization of diterpene synthases from basidiomycete fungi by genome mining 期刊论文
FUNGAL GENETICS AND BIOLOGY, 2019, 卷号: 128, 页码: 36-42
作者:  Li, Xin-Lin;  Xu, Yu-Xing;  Li, Yuan;  Zhang, Rui;  Hu, Tian-Yuan;  Su, Ping;  Zhou, Man;  Tang, Ting;  Zeng, Ying;  Yang, Yan-Long;  Gao, Wei
浏览  |  Adobe PDF(1544Kb)  |  收藏  |  浏览/下载：220/39  |  提交时间：2019/07/29
Basidiomycete  Ditepene synthase  Genome mining  Cembrane diterpene  (-)-cyatha-3,12-diene  Ent-kauran-16 alpha-ol  
Synthesis and structure-activity relationship studies of water-soluble beta-cyclodextrin-glycyrrhetinic acid conjugates as potential anti-influenza virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 328-338
作者:  Liang, Shuobin;  Li, Man;  Yu, Xiaojuan;  Jin, Hongwei;  Zhang, Yongmin;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
浏览  |  Adobe PDF(1284Kb)  |  收藏  |  浏览/下载：220/27  |  提交时间：2019/04/15
Glycyrrhetinic acid  Cyclodextrin  Click reaction  Influenza virus  Inhibitors  
Facile preparation and characterization of novel oleanane-type triterpene functionalized beta-cyclodextrin conjugates 期刊论文
CHINESE CHEMICAL LETTERS, 2019, 卷号: 30, 期号: 3, 页码: 690-693
作者:  Jiao, Pingxuan;  Wang, Shouxin;  Liang, Shuobin;  Li, Man;  Gao, Qianqian;  Ji, Dezhong;  Chen, Yingying;  Li, Haiwei;  Ran, Fuxiang;  Zhang, Yongmin;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
浏览  |  Adobe PDF(1169Kb)  |  收藏  |  浏览/下载：155/46  |  提交时间：2019/07/29
beta-Cyclodextrin  DIBAL-H  Oleanolic acid  Echinocystic acid  Synthesis  
Synthesis, structure activity relationship and in vitro anti-influenza virus activity of novel polyphenol-pentacyclic triterpene conjugates 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163, 页码: 560-568
作者:  Li, Haiwei;  Li, Man;  Xu, Renyang;  Wang, Shouxin;  Zhang, Yongmin;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
浏览  |  Adobe PDF(1830Kb)  |  收藏  |  浏览/下载：152/27  |  提交时间：2019/03/25
Influenza virus  Pentacyclic triterpene  Polyphenol  Entry inhibitor  Hemagglutinin  
Protein Aggregation and Performance Optimization Based on Microconformational Changes of Aromatic Hydrophobic Regions 期刊论文
MOLECULAR PHARMACEUTICS, 2018, 卷号: 15, 期号: 6, 页码: 2257-2267
作者:  Wen, Lili;  Lyu, Man;  Xiao, Huashuai;  Lan, Hairong;  Zuo, Zhili;  Yin, Zongning
收藏  |  浏览/下载：112/0  |  提交时间：2018/07/16
Protein Aggregation  Aromatic Hydrophobic Regions  Amine Compounds  Guanidine Compounds  Microconformational Change  
Old drug, new indication: Olsalazine sodium reduced serum uric acid levels in mice via inhibiting xanthine oxidoreductase activity 期刊论文
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2017, 卷号: 135, 期号: 3, 页码: 114-120
作者:  Niu, Yanfen;  Li, Hongjian;  Gao, Lihui;  Lin, Hua;  Kung, Hsiangfu;  Lin, Marie Chia-mi;  Leung, Kwong-Sak;  Wong, Man-Hon;  Xiong, Wenyong;  Li, Ling
收藏  |  浏览/下载：89/0  |  提交时间：2018/05/08
Olsalazine Sodium  Hyperuricemia  Xanthine Oxidase  Uric Acid  
Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 期号: 0, 页码: 42176
作者:  Li, Mingyue;  Song, Li-Hua;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Zhao, Li-Mei;  Li, Lin;  Zhou, Xunian;  Tsui, Stephen Kwok-Wing;  Ng, Simon Siu-Man;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
浏览  |  Adobe PDF(3294Kb)  |  收藏  |  浏览/下载：187/40  |  提交时间：2017/04/17
Racemic alkaloids from the fungus Ganoderma cochlear 期刊论文
FITOTERAPIA, 2017, 卷号: 116, 期号: 1, 页码: 93-98
作者:  Wang, Xin-Long;  Dou, Man;  Luo, Qi;  Cheng, Li-Zhi;  Yan, Yong-Ming;  Li, Rong-Tao;  Cheng, Yong-Xian
浏览  |  Adobe PDF(445Kb)  |  收藏  |  浏览/下载：193/66  |  提交时间：2017/04/18
Ganoderma Cochlear  Alkaloids  Ecd Calculations  Racemates  Biosynthesis  
Diocollettines A, an unusual tricyclic diarylheptanoid derivative from the rhizomes of Dioscorea collettii 期刊论文
TETRAHEDRON LETTERS, 2016, 卷号: 57, 期号: 29, 页码: 3215-3217
作者:  Jing, Song-Song;  Wang, Ying;  Yan, Yong-Ming;  Li, Xia;  Li, Xue-Jiao;  Zhao, Cheng-Cheng;  Sun, Jia-Chen;  Qiu, Pei-Yu;  Man, Shu-Li;  Gao, Wen-Yuan
浏览  |  Adobe PDF(542Kb)  |  收藏  |  浏览/下载：244/49  |  提交时间：2016/09/28
Tricyclic Diarylheptanoid  Dioscorea Collettii  Absolute Configuration  Cytotoxicity