| Racemic alkaloids from the fungus Ganoderma cochlear | |
Wang, Xin-Long1,2; Dou, Man2,3; Luo, Qi2 ; Cheng, Li-Zhi2,4; Yan, Yong-Ming2; Li, Rong-Tao3; Cheng, Yong-Xian1,2
| |
| 2017 | |
| Source Publication | FITOTERAPIA
 |
| Volume | 116Issue:1Pages:93-98 |
| Abstract | Seven pairs of new alkaloid enantiomers, ganocochlearines C-I (1, 3-8), and three pairs of known alkaloids were isolated from the fruiting bodies of Ganoderma cochlear. The chemical structures of new compounds were elucidated on the basis of 1D and 2D NMR data. The absolute configurations of compounds 1,3-10 were assigned by ECD calculations. Biological activities of these isolates against renal fibrosis were accessed in rat normal or diseased renal interstitial fibroblast cells. Importantly, the plausible biosynthetic pathway for this class of alkaloids was originally proposed. (C) 2016 Elsevier B.V. All rights reserved. |
| Keyword | Ganoderma Cochlear Alkaloids Ecd Calculations Racemates Biosynthesis |
| DOI | 10.1016/j.fitote.2016.11.011 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000392779200014 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/45766 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Henan Univ Tradit Chinese Med, Zhengzhou 450008, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 3.Kunming Univ Sci & Technol, Fac Life Sci & Engn, Kunming 650500, Peoples R China 4.Guangdong Pharmaceut Univ, Guangzhou 510006, Guangdong, Peoples R China |
| Recommended Citation GB/T 7714 | Wang, Xin-Long,Dou, Man,Luo, Qi,et al. Racemic alkaloids from the fungus Ganoderma cochlear[J]. FITOTERAPIA,2017,116(1):93-98. |
| APA | Wang, Xin-Long.,Dou, Man.,Luo, Qi.,Cheng, Li-Zhi.,Yan, Yong-Ming.,...&Cheng, Yong-Xian.(2017).Racemic alkaloids from the fungus Ganoderma cochlear.FITOTERAPIA,116(1),93-98. |
| MLA | Wang, Xin-Long,et al."Racemic alkaloids from the fungus Ganoderma cochlear".FITOTERAPIA 116.1(2017):93-98. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| 1-s2.0-S0367326X1630（445KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment