Racemic alkaloids from the fungus Ganoderma cochlear
Wang, Xin-Long1,2; Dou, Man2,3; Luo, Qi2; Cheng, Li-Zhi2,4; Yan, Yong-Ming2; Li, Rong-Tao3; Cheng, Yong-Xian1,2
2017
Source PublicationFITOTERAPIA
Volume116Issue:1Pages:93-98
AbstractSeven pairs of new alkaloid enantiomers, ganocochlearines C-I (1, 3-8), and three pairs of known alkaloids were isolated from the fruiting bodies of Ganoderma cochlear. The chemical structures of new compounds were elucidated on the basis of 1D and 2D NMR data. The absolute configurations of compounds 1,3-10 were assigned by ECD calculations. Biological activities of these isolates against renal fibrosis were accessed in rat normal or diseased renal interstitial fibroblast cells. Importantly, the plausible biosynthetic pathway for this class of alkaloids was originally proposed. (C) 2016 Elsevier B.V. All rights reserved.
KeywordGanoderma Cochlear Alkaloids Ecd Calculations Racemates Biosynthesis
DOI10.1016/j.fitote.2016.11.011
Indexed BySCI
Language英语
WOS IDWOS:000392779200014
Citation statistics
Cited Times:15[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/45766
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Henan Univ Tradit Chinese Med, Zhengzhou 450008, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
3.Kunming Univ Sci & Technol, Fac Life Sci & Engn, Kunming 650500, Peoples R China
4.Guangdong Pharmaceut Univ, Guangzhou 510006, Guangdong, Peoples R China
Recommended Citation
GB/T 7714
Wang, Xin-Long,Dou, Man,Luo, Qi,et al. Racemic alkaloids from the fungus Ganoderma cochlear[J]. FITOTERAPIA,2017,116(1):93-98.
APA Wang, Xin-Long.,Dou, Man.,Luo, Qi.,Cheng, Li-Zhi.,Yan, Yong-Ming.,...&Cheng, Yong-Xian.(2017).Racemic alkaloids from the fungus Ganoderma cochlear.FITOTERAPIA,116(1),93-98.
MLA Wang, Xin-Long,et al."Racemic alkaloids from the fungus Ganoderma cochlear".FITOTERAPIA 116.1(2017):93-98.
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