Racemic alkaloids from the fungus Ganoderma cochlear
Wang, Xin-Long1,2; Dou, Man2,3; Luo, Qi2; Cheng, Li-Zhi2,4; Yan, Yong-Ming2; Li, Rong-Tao3; Cheng, Yong-Xian1,2
Source PublicationFITOTERAPIA
AbstractSeven pairs of new alkaloid enantiomers, ganocochlearines C-I (1, 3-8), and three pairs of known alkaloids were isolated from the fruiting bodies of Ganoderma cochlear. The chemical structures of new compounds were elucidated on the basis of 1D and 2D NMR data. The absolute configurations of compounds 1,3-10 were assigned by ECD calculations. Biological activities of these isolates against renal fibrosis were accessed in rat normal or diseased renal interstitial fibroblast cells. Importantly, the plausible biosynthetic pathway for this class of alkaloids was originally proposed. (C) 2016 Elsevier B.V. All rights reserved.
KeywordGanoderma Cochlear Alkaloids Ecd Calculations Racemates Biosynthesis
Indexed BySCI
WOS IDWOS:000392779200014
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Document Type期刊论文
Affiliation1.Henan Univ Tradit Chinese Med, Zhengzhou 450008, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
3.Kunming Univ Sci & Technol, Fac Life Sci & Engn, Kunming 650500, Peoples R China
4.Guangdong Pharmaceut Univ, Guangzhou 510006, Guangdong, Peoples R China
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GB/T 7714
Wang, Xin-Long,Dou, Man,Luo, Qi,et al. Racemic alkaloids from the fungus Ganoderma cochlear[J]. FITOTERAPIA,2017,116(1):93-98.
APA Wang, Xin-Long.,Dou, Man.,Luo, Qi.,Cheng, Li-Zhi.,Yan, Yong-Ming.,...&Cheng, Yong-Xian.(2017).Racemic alkaloids from the fungus Ganoderma cochlear.FITOTERAPIA,116(1),93-98.
MLA Wang, Xin-Long,et al."Racemic alkaloids from the fungus Ganoderma cochlear".FITOTERAPIA 116.1(2017):93-98.
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