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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：187/39  |  提交时间：2020/03/26
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1740Kb)  |  收藏  |  浏览/下载：183/21  |  提交时间：2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：225/68  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3915Kb)  |  收藏  |  浏览/下载：209/40  |  提交时间：2019/07/29
Prophylactic Effects of Bifidobacterium adolescentis on Anxiety and Depression-Like Phenotypes After Chronic Stress: A Role of the Gut Microbiota-Inflammation Axis 期刊论文
FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 2019, 卷号: 13, 页码: 17
作者:  Guo, Ying;  Xie, Jian-Ping;  Deng, Ke;  Li, Xia;  Yuan, Yun;  Xuan, Qun;  Xie, Jing;  He, Xiao-Ming;  Wang, Qian;  Li, Juan-Juan;  Luo, Huai-Rong
浏览  |  Adobe PDF(4609Kb)  |  收藏  |  浏览/下载：177/27  |  提交时间：2019/07/29
Bifidobacterium adolescentis  antidepressant  chronic restraint stress  gut microbiota  inflammation  
Sense Ginsenosides From Ginsengs: Structure-Activity Relationship in Autophagy 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2019, 卷号: 14, 期号: 6, 页码: 10
作者:  Wu, Tao;  Kwaku, Osafo Raymond;  Li, Hai-Zhou;  Yang, Chong-Ren;  Ge, Long-Jiao;  Xu, Min
浏览  |  Adobe PDF(1069Kb)  |  收藏  |  浏览/下载：160/35  |  提交时间：2019/09/10
ginsengs  ginsenosides  structure-activity relationship  autophagy  
RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 14
作者:  Guo, Di;  Wang, Yurong;  Wang, Jing;  Song, Lihua;  Wang, Zhe;  Mao, Bingyu;  Tan, Ninghua
浏览  |  Adobe PDF(9639Kb)  |  收藏  |  浏览/下载：138/25  |  提交时间：2019/07/29
RA-XII  lipogenesis  SCAP  SREBP  liver cancer  
Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176
作者:  Li, Yingying;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Liu, Xingyong;  Zhang, Li;  Wang, Liang-Liang;  Zuo, Zhili
浏览  |  Adobe PDF(7335Kb)  |  收藏  |  浏览/下载：228/25  |  提交时间：2019/07/29
Pharmacophore modeling  Molecular docking  Quantitative structure activity relationship (QSAR)  Molecular dynamics  AMPK  Activator  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
浏览  |  Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：152/34  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
作者:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(4782Kb)  |  收藏  |  浏览/下载：159/58  |  提交时间：2019/07/29