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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
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Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Phenolic compounds from the insect Blaps japanensis with inhibitory activities towards cancer cells, COX-2, ROCK1 and JAK3 期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 8, 页码: 1029-1033
作者:  Yan, Yong-Ming;  Zhu, Hong-Jie;  Zhou, Feng-Jiao;  Tu, Zheng-Chao;  Cheng, Yong-Xian
浏览  |  Adobe PDF(458Kb)  |  收藏  |  浏览/下载：195/45  |  提交时间：2019/03/25
Insect  Blaps japanensis  Phenolic compounds  Cytotoxicity  COX-2  ROCK1  JAK3  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
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Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Emeridones A-F, a Series of 3,5-Demethylorsellinic Acid-Based Meroterpenoids with Rearranged Skeletons from an Endophytic Fungus Emericella sp. TJ29 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 84, 期号: 3, 页码: 1534-1541
作者:  Li, Qin;  Chen, Chunmei;  Cheng, Li;  Wei, Mengsha;  Dai, Chong;  He, Yan;  Gong, Jiaojiao;  Zhu, Runqi;  Li, Xiao-Nian;  Liu, Junjun;  Wang, Jianping;  Zhu, Hucheng;  Zhang, Yonghui
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Synthesis, structure activity relationship and in vitro anti-influenza virus activity of novel polyphenol-pentacyclic triterpene conjugates 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163, 页码: 560-568
作者:  Li, Haiwei;  Li, Man;  Xu, Renyang;  Wang, Shouxin;  Zhang, Yongmin;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
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Influenza virus  Pentacyclic triterpene  Polyphenol  Entry inhibitor  Hemagglutinin  
Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 3, 页码: 771-775
作者:  Tang, Jian-Wei;  Kong, Ling-Mei;  Zu, Wen-Yu;  Hu, Kun;  Li, Xiao-Nian;  Yan, Bing-Chao;  Wang, Wei-Guang;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
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Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
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Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Leucoflavonine, a new bioactive racemic flavoalkaloid from the leaves of Leucosceptrum canum 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 2, 页码: 442-446
作者:  Feng, Ling;  Zhang, Yu;  Liu, Yan-Chun;  Liu, Yan;  Luo, Shi-Hong;  Huang, Chun-Shuai;  Li, Sheng-Hong
浏览  |  Adobe PDF(1106Kb)  |  收藏  |  浏览/下载：151/28  |  提交时间：2019/03/18
Leucosceptrum canum  Lamiaceae  Flavoalkaloid  Leucoflavonine  Biological activities  
Maoeriocalysins A-D, four novel ent-kaurane diterpenoids from Isodon eriocalyx and their structure determination utilizing quantum chemical calculation in conjunction with quantitative interproton distance analysis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 1, 页码: 45-53
作者:  Yang, Qian;  Hu, Kun;  Yan, Bing-Chao;  Liu, Miao;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
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Cytotoxic Effects of Compounds Isolated from Ricinodendron heudelotii 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 11
作者:  Yakubu, Omolara F.;  Adebayo, Abiodun H.;  Dokunmu, Titilope M.;  Zhang, Ying-Jun;  Iweala, Emeka E. J.
浏览  |  Adobe PDF(1826Kb)  |  收藏  |  浏览/下载：162/24  |  提交时间：2019/03/18
anticancer  Ricinodendron heudelotii  chemoprevention