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Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：162/28  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：178/37  |  提交时间：2020/03/26
Structure and heparanase inhibitory activity of a new glycosaminoglycan from the slug Limacus flavus 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 220, 页码: 176-184
作者:  He, Zhicheng;  Zhou, Lutan;  Lin, Lisha;  Yin, Ronghua;  Zhao, Jinhua
浏览  |  Adobe PDF(1875Kb)  |  收藏  |  浏览/下载：158/20  |  提交时间：2019/07/29
Slug  Glycosaminoglycan  Chemical structure  Depolymerization  Heparanase inhibition  
Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.;  Wang, Wei-Guang;  Sun, Han-Dong;  Lillico, Ryan;  Lakowski, Ted M.;  Siahaan, Teruna J.;  Davies, Neal M.;  Puno, Pema-Tenzin;  Vanan, Magimairajan Issai;  Miller, Donald W.
浏览  |  Adobe PDF(3895Kb)  |  收藏  |  浏览/下载：185/46  |  提交时间：2019/12/20
blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma  
Anti-inflammatory Effect of Pomelo Peel and Its Bioactive Coumarins 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 32, 页码: 8810-8818
作者:  Zhao, Yun-Li;  Yang, Xiong-Wu;  Wu, Bai-Fen;  Shang, Jian-Hua;  Liu, Ya-Ping;  Zhi-Dai;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1099Kb)  |  收藏  |  浏览/下载：125/38  |  提交时间：2019/10/14
C. grandis  coumarins  anti-inflammatory effect  lipopolysaccharide  
Recombinant polyphenol oxidases for production of theaflavins from tea polyphenols 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 134, 页码: 139-145
作者:  Zeng, Jun;  Du, Gang;  Shao, Xue;  Feng, Ke-Na;  Zeng, Ying
浏览  |  Adobe PDF(1259Kb)  |  收藏  |  浏览/下载：131/36  |  提交时间：2019/08/19
Theaflavins  Recombinant polyphenol oxidase  Mesoporous silica  
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3136Kb)  |  收藏  |  浏览/下载：154/55  |  提交时间：2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：218/67  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1101Kb)  |  收藏  |  浏览/下载：216/99  |  提交时间：2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Renoprotective phenolic meroterpenoids from the mushroom Ganoderma cochlear 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 页码: 199-206
作者:  Wang, Xin-Long;  Wu, Ze-Hong;  Di, Lei;  Zhou, Feng-Jiao;  Yan, Yong-Ming;  Cheng, Yong-Xian
浏览  |  Adobe PDF(1343Kb)  |  收藏  |  浏览/下载：150/43  |  提交时间：2019/07/29
Ganoderma cochlear (Ganodermataceae)  Meroterpenoid  Calculated ECD  Renoprotection