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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
作者:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  收藏  |  浏览/下载：260/1  |  提交时间：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
Phenolic compounds from the insect Blaps japanensis with inhibitory activities towards cancer cells, COX-2, ROCK1 and JAK3 期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 8, 页码: 1029-1033
作者:  Yan, Yong-Ming;  Zhu, Hong-Jie;  Zhou, Feng-Jiao;  Tu, Zheng-Chao;  Cheng, Yong-Xian
浏览  |  Adobe PDF(458Kb)  |  收藏  |  浏览/下载：206/46  |  提交时间：2019/03/25
Insect  Blaps japanensis  Phenolic compounds  Cytotoxicity  COX-2  ROCK1  JAK3  
Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 189-199
作者:  Li, Mingyue;  Yue, Grace Gar-Lee;  Song, Li-Hua;  Huang, Mao-Bo;  Lee, Julia Kin-Ming;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
浏览  |  Adobe PDF(2333Kb)  |  收藏  |  浏览/下载：173/38  |  提交时间：2018/07/02
Bigelovin  Colorectal Cancer  Metastasis  Tumor Microenvironment  Ll6/stat3 Pathway  
Two New Compounds from Medicinal Insect Blaps japanensis and Their Biological Evaluation 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2018, 卷号: 13, 期号: 2, 页码: 149-151
作者:  Zheng, Tao;  Ming, Yan-Yong;  Tu, Zheng-Chao;  Xu, Fu Rong;  Cheng, Yong-Xian
收藏  |  浏览/下载：82/0  |  提交时间：2018/07/16
Blaps Japanensis  Insect  Pipajiains f And g  Biological Evaluation  
Phenolic derivatives from Blaps japanensis and their biological evaluation 期刊论文
FITOTERAPIA, 2017, 卷号: 120, 页码: 58-60
作者:  Zheng, Tao;  Yan, Yong-Ming;  Tu, Zheng-Chao;  Luo, Qi;  Xu, Fu-Rong;  Cheng, Yong-Xian
浏览  |  Adobe PDF(294Kb)  |  收藏  |  浏览/下载：202/71  |  提交时间：2017/10/23
Blaps Japanensis  Insect  Biological Evaluation  Phenolic Derivatives  
Compounds from Polyphaga plancyi and their inhibitory activities against JAK3 and DDR1 kinases 期刊论文
FITOTERAPIA, 2016, 卷号: 114, 页码: 163-167
作者:  Zhu, Hong-Jie;  Yan, Yong-Ming;  Tu, Zheng-Chao;  Luo, Jin-Feng;  Liang, Rui;  Yang, Tong-Hua;  Cheng, Yong-Xian;  Wang, Shu-Mei
浏览  |  Adobe PDF(448Kb)  |  收藏  |  浏览/下载：202/66  |  提交时间：2017/01/05
Polyphaga Plancyi Bolivar  Insect  Computational Methods  Jak3  Ddr1  
RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Leung,Hoi-Wing;  Zhao,Si-Meng;  Yue,Grace Gar-Lee;  Lee,Julia Kin-Ming;  Fung,Kwok-Pui;  Leung,Ping-Chung;  Tan,Ning-Hua;  Lau,Clara Bik-San
浏览  |  Adobe PDF(2369Kb)  |  收藏  |  浏览/下载：182/50  |  提交时间：2016/01/19
Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-kappa B signaling pathways 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2015, 卷号: 1853, 期号: 8, 页码: 1827-1840
作者:  Leung, Hoi-Wing;  Wang, Zhe;  Yue, Grace Gar-Lee;  Zhao, Si-Meng;  Lee, Julia Kin-Ming;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Lau, Clara Bik-San;  Tan, Ning-Hua;  Lau,CBS (reprint author),Chinese Univ Hong Kong,Inst Chinese Med,Shatin,Hong Kong,Peoples R China.;  claralau@cuhk.edu.hk;  nhtan@mail.kib.ac.cn
浏览  |  Adobe PDF(2434Kb)  |  收藏  |  浏览/下载：285/45  |  提交时间：2015/07/20
Cyclopeptide  Cell Adhesion  Cell Invasion  Metastasis  Breast Cancer  
Dopamine derivatives from the insect Polyrhachis dives as inhibitors of ROCK1/2 and stimulators of neural stem cell proliferation 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 46, 页码: 8852-8857
作者:  Tang, Jian-Jun ab;  Zhang, Li;  Jiang, Li-Ping;  Di, Lei;  Yan, Yong-Ming;  Tu, Zheng-Chao;  Yang, Cui-Ping;  Zuo, Zhi-Li;  Hou, Bo;  Xia, Hou-Lin;  Chen, Yong-Bin;  Cheng, Yong-Xian;  Tu,ZC (reprint author),Chinese Acad Sci,Guangzhou Inst Biomed & Hlth,Key Lab Regenerat Biol,Guangzhou 510530,Guangdong,Peoples R China.;  tu_zhengchao@gibh.ac.cn;  ybchen@mail.kiz.ac.cn;  yxcheng@mail.kib.ac.cn
浏览  |  Adobe PDF(678Kb)  |  收藏  |  浏览/下载：436/94  |  提交时间：2015/01/20
Polyrhachis Dives  Dopamine Derivative  Rock1/2 Inhibitors  Nscs