Two New Compounds from Medicinal Insect Blaps japanensis and Their Biological Evaluation
Zheng, Tao1,3; Ming, Yan-Yong1,4; Tu, Zheng-Chao5; Xu, Fu Rong3; Cheng, Yong-Xian1,2,4
2018-02-01
Source PublicationNATURAL PRODUCT COMMUNICATIONS
ISSN1934-578X
Volume13Issue:2Pages:149-151
AbstractNaps japanensis is a medicinal insect used for the treatment of a variety of disorders in Yi-nationality of Yunnan province, China. In the present study, two new compounds, named pipajiains F and G (1 and 2), along with four known compounds, 3-indolealdehyde (3), L-tryptophan (4), ginsenine (5), and anoectochine (6) were isolated from B. japanensis. Their structures were identified on the basis of spectroscopic methods. Compound 1 is a phenolic compound bearing a pyridine-1-ium-1carboxylate motif in the structure which made 1 an unusual architecture. Compounds 2 is an indole alkaloid derivative. Biological activities of all these compounds towards COX-2, ROCK1/2, and JAK3 kinases were evaluated.
KeywordBlaps Japanensis Insect Pipajiains f And g Biological Evaluation
Language英语
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/61348
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China
2.Henan Univ Chinese Med, Zhengzhou 450008, Henan, Peoples R China
3.Yunnan Univ Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China
4.Shenzhen Univ, Gziangdong Key Lab Genome Stabil & Dis Prevent, Sch Pharmaceut Sci, Sch Med,Hlth Sci Ctr, Shenzhen 518060, Peoples R China
5.Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510530, Guangdong, Peoples R China
Recommended Citation
GB/T 7714
Zheng, Tao,Ming, Yan-Yong,Tu, Zheng-Chao,et al. Two New Compounds from Medicinal Insect Blaps japanensis and Their Biological Evaluation[J]. NATURAL PRODUCT COMMUNICATIONS,2018,13(2):149-151.
APA Zheng, Tao,Ming, Yan-Yong,Tu, Zheng-Chao,Xu, Fu Rong,&Cheng, Yong-Xian.(2018).Two New Compounds from Medicinal Insect Blaps japanensis and Their Biological Evaluation.NATURAL PRODUCT COMMUNICATIONS,13(2),149-151.
MLA Zheng, Tao,et al."Two New Compounds from Medicinal Insect Blaps japanensis and Their Biological Evaluation".NATURAL PRODUCT COMMUNICATIONS 13.2(2018):149-151.
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