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Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.;  Wang, Wei-Guang;  Sun, Han-Dong;  Lillico, Ryan;  Lakowski, Ted M.;  Siahaan, Teruna J.;  Davies, Neal M.;  Puno, Pema-Tenzin;  Vanan, Magimairajan Issai;  Miller, Donald W.
Adobe PDF(3895Kb)  |  收藏  |  浏览/下载：199/48  |  提交时间：2019/12/20
blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：290/63  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载：211/0  |  提交时间：2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC  
Diterpenoids from Isodon species: an update 期刊论文
NATURAL PRODUCT REPORTS, 2017, 卷号: 34, 期号: 9, 页码: 1090-1140
作者:  Liu, Miao;  Wang, Wei-Guang;  Sun, Han-Dong;  Pu, Jian-Xin
浏览  |  Adobe PDF(10292Kb)  |  收藏  |  浏览/下载：253/29  |  提交时间：2017/10/23
Ent-kaurane Diterpenoids  Japonica Var. Glaucocalyx  Nf-kappa-b  Hepatocellular-carcinoma Cells  C-h Functionalization  Dna-binding Activity  Serra Maxim. Hara  Maoecrystal-v  Abietane Diterpenoids  Chemical-constituents  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
浏览  |  Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：443/205  |  提交时间：2017/02/28
Eriocalyxin B, a Novel Autophagy Inducer, Exerts Anti-tumor Activity Through the Suppression of Akt/mTOR/p70S6K Signaling Pathway In breast Cancer 期刊论文
Biochemical Pharmacology, 2017, 卷号: 142, 页码: 58–70
作者:  Xunian Zhou;  Grace Gar-Lee Yue;  Andrew Man-Lok Chan;   Stephen Kwok-Wing Tsui;  Kwok-Pui Fung;   Handong Sun;  Jianxin Pu;  Clara Bik-San Lau
Adobe PDF(5871Kb)  |  收藏  |  浏览/下载：199/51  |  提交时间：2017/11/20
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
Adobe PDF(13632Kb)  |  收藏  |  浏览/下载：291/33  |  提交时间：2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Bioactive ent-kaurane diterpenoids from Isodon serra 期刊论文
PHYTOCHEMISTRY, 2016, 卷号: 130, 页码: 244-251
作者:  Wan, Jun;  Liu, Miao;  Jiang, Hua-Yi;  Yang, Jin;  Du, Xue;  Li, Xiao-Nian;  Wang, Wei-Guang;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(653Kb)  |  收藏  |  浏览/下载：460/79  |  提交时间：2016/11/04
Isodon Serra  Lamiaceae  Cytotoxic Activity  7  Anti-inflammatory  20-epoxy-ent-kaurane Diterpenoids  
Bioactive Enmein-Type ent-Kaurane Diterpenoids from Isodon phyllostachys 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 132-140
作者:  Yang, Jin;  Wang, Wei-Guang;  Wu, Hai-Yan;  Du, Xue;  Li, Xiao-Nian;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(1386Kb)  |  收藏  |  浏览/下载：388/82  |  提交时间：2016/06/27
SJP-L-5, a novel small-molecule compound, inhibits HIV-1 infection by blocking viral DNA nuclear entry 期刊论文
BMC MICROBIOLOGY, 2015, 卷号: 15
作者:  Bai,Ru;  Zhang,Xing-Jie;  Li,Yan-Li;  Liu,Jing-Ping;  Zhang,Hong-Bin;  Xiao,Wei-Lie;  Pu,Jian-Xin;  Sun,Han-Dong;  Zheng,Yong-Tang;  Liu,Li-Xin
浏览  |  Adobe PDF(2540Kb)  |  收藏  |  浏览/下载：199/49  |  提交时间：2016/01/19
Hiv-1  Pre-integration Complex  Nuclear Entry  Capsid  Sjp-l-5