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Biomimetic Intramolecular Diels-Alder Reaction to Construct the Tetrahydroindane Core of Elansolid A1/A2 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 7, 页码: 2820-2830
作者:  Yu Qi;  Yang Shuai;  Tang Congyun;  Peng Lin;  Zuo Zhili;  Wang Liangliang
浏览  |  Adobe PDF(657Kb)  |  收藏  |  浏览/下载：99/31  |  提交时间：2022/04/02
biomimetic synthesis  Diels-Alder reaction  tetrahydroindane  elansolid  ACID  OLEFIN  
Enantioselective access to tricyclic tetrahydropyran derivatives by a remote hydrogen bonding mediated intramolecular IEDHDA reaction 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 7188
作者:  Jin,Min;  Tang,Congyun;  Li,Yingying;  Yang,Shuai;  Yang,Ying-Tao;  Peng,Lin;  Li,Xiao-Nian;  Zhang,Wenjing;  Zuo,Zhili;  Gagosz,Fabien;  Wang,Liang-Liang
浏览  |  Adobe PDF(2328Kb)  |  收藏  |  浏览/下载：127/20  |  提交时间：2022/04/02
DIELS-ALDER REACTION  BIOMIMETIC TOTAL-SYNTHESIS  ORTHO-QUINONE METHIDES  BRONSTED ACID  CYCLIZATION  ACTIVATION  OLEFINS  CYCLOADDITIONS  CATALYSIS  ENTRY  
Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 166, 页码: 105527
作者:  Zhou,Lutan;  Yin,Ronghua;  Gao,Na;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Ren,Lin;  Yang,Lian;  Zuo,Zhili;  Zhang,Hongbin;  Zhao,Jinhua
浏览  |  Adobe PDF(8336Kb)  |  收藏  |  浏览/下载：90/11  |  提交时间：2022/04/02
Oligosaccharides  Heparanase  Angiogenesis  Metastasis  FIBROBLAST-GROWTH-FACTOR  TUMOR-GROWTH  SULFATE PROTEOGLYCANS  MAMMALIAN HEPARANASE  COMBINATION  MECHANISMS  DISCOVERY  BINDING  TARGET  PI-88  
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives 期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
作者:  Yin,Ronghua;  Zhou,Lutan;  Gao,Na;  Lin,Lisha;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Zuo,Zhili;  Hu,Kaifeng;  Huang,Shengxiong;  Liu,Jikai;  Zhao,Jinhua
浏览  |  Adobe PDF(4401Kb)  |  收藏  |  浏览/下载：107/25  |  提交时间：2022/04/02
FUCOSYLATED CHONDROITIN SULFATE  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  SEA-CUCUMBER  FUCOSE BRANCHES  BODY-WALL  INDEPENDENT INHIBITION  POLYSACCHARIDE ACCOUNT  FACTOR XASE  HEPARIN  
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
浏览  |  Adobe PDF(4714Kb)  |  收藏  |  浏览/下载：325/42  |  提交时间：2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
阿片类药物研发近期热点 期刊论文
有机化学, 2018, 页码: 10
作者:  潘陈玲;  孟浩;  汪亮亮;  沈悦海;  左之利;  王冠林;  张宽仁
收藏  |  浏览/下载：125/0  |  提交时间：2018/11/26
阿片药物  阿片受体  阿片样副作用  药物研究  
Comparative QSAR studies using HQSAR, CoMFA, and CoMSIA methods on cyclic sulfone hydroxyethylamines as BACE1 inhibitors 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2017, 卷号: 67, 期号: 1, 页码: 38-47
作者:  Zhang, Shuqun;  Lin, Zichun;  Pu, Yinglan;  Zhang, Yunqin;  Zhang, Li;  Zuo, Zhili
浏览  |  Adobe PDF(1591Kb)  |  收藏  |  浏览/下载：308/64  |  提交时间：2017/05/19
Bace1  Ad  Hqsar  Comfa  Comsia  
Clinoposides A-F: meroterpenoids with protective effects on H9c2 cardiomyocyte from Clinopodium chinense 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 9, 页码: 7260-7266
作者:  Zhu, Yin-Di;  Wu, Hai-Feng;  Ma, Guo-Xu;  Chen, Rong-Chang;  Long, Hai-Lin;  Zuo, Zhi-Li;  Luo, Yun;  Zhu, Nai-Liang;  Hou, Bo;  Xu, Xu-Dong;  Sun, Gui-Bo;  Yang, Jun-Shan
浏览  |  Adobe PDF(1215Kb)  |  收藏  |  浏览/下载：199/55  |  提交时间：2016/06/27
Ganocochlearic acid A, a rearranged hexanorlanostane triterpenoid, and cytotoxic triterpenoids from the fruiting bodies of Ganoderma cochlear 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 115, 页码: 95212-95222
作者:  Peng, Xing-Rong;  Wang, Xia;  Zhou, Lin;  Hou, Bo;  Zuo, Zhi-Li;  Qiu, Ming-Hua
浏览  |  Adobe PDF(1014Kb)  |  收藏  |  浏览/下载：194/45  |  提交时间：2016/01/19
Dopamine derivatives from the insect Polyrhachis dives as inhibitors of ROCK1/2 and stimulators of neural stem cell proliferation 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 46, 页码: 8852-8857
作者:  Tang, Jian-Jun ab;  Zhang, Li;  Jiang, Li-Ping;  Di, Lei;  Yan, Yong-Ming;  Tu, Zheng-Chao;  Yang, Cui-Ping;  Zuo, Zhi-Li;  Hou, Bo;  Xia, Hou-Lin;  Chen, Yong-Bin;  Cheng, Yong-Xian;  Tu,ZC (reprint author),Chinese Acad Sci,Guangzhou Inst Biomed & Hlth,Key Lab Regenerat Biol,Guangzhou 510530,Guangdong,Peoples R China.;  tu_zhengchao@gibh.ac.cn;  ybchen@mail.kiz.ac.cn;  yxcheng@mail.kib.ac.cn
Adobe PDF(678Kb)  |  收藏  |  浏览/下载：461/97  |  提交时间：2015/01/20
Polyrhachis Dives  Dopamine Derivative  Rock1/2 Inhibitors  Nscs