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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载:4/1  |  提交时间:2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Steroidal alkaloid with unprecedented triheterocyclic architecture 期刊论文
CHEMICAL COMMUNICATIONS, 2023, 卷号: 59, 期号: 3, 页码: 326-329
作者:  Zhou,Zhong-Shun;  Zhao,Yun-Li;  Hu,Bin-Yuan;  Wang,Bei;  Liu,Ya-Ping;  Zhu,Yan-Yan;  He,Ying-Jie;  Wang,Zhao-Jie;  Dai,Zhi;  Zhao,Li-Xing;  Luo,Xiao-Dong
Adobe PDF(975Kb)  |  收藏  |  浏览/下载:12/2  |  提交时间:2024/07/22
MALIC-ACID  SKELETON  
Dimeric benzylisoquinoline alkaloids from Thalictrum delavayi and their biological activities 期刊论文
FITOTERAPIA, 2023, 卷号: 164, 页码: 105356
作者:  Jin,Qiong;  Qin,Xu-Jie;  Dai,Zhi;  Zhao,Yun;  Zhu,Yan-Yan;  Chen,Shan-Shan;  Liu,Ya-Ping;  Luo,Xiao-Dong
Adobe PDF(1861Kb)  |  收藏  |  浏览/下载:6/3  |  提交时间:2024/07/25
Thalictrum delavayi  Ranunculaceae  Bisbenzylisoquinoline alkaloids  Cytotoxicities  Immunosuppressive effects  CYCLOARTANE GLYCOSIDES  APORPHINE  LEAVES  PLANTS  
Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
作者:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
浏览  |  Adobe PDF(4759Kb)  |  收藏  |  浏览/下载:46/10  |  提交时间:2024/04/30
Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
Phenolic Amides with Immunomodulatory Activity from the Nonpolysaccharide Fraction of Lycium barbarum Fruits 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
作者:  Zhu, Pei-Feng;  Zhao, Yun-Li;  Dai, Zhi;  Qin, Xu-Jie;  Yuan, Hai-Lian;  Jin, Qiong;  Wang, Yi-Fen;  Liu, Ya-Ping;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1621Kb)  |  收藏  |  浏览/下载:219/84  |  提交时间:2021/01/05
Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii 期刊论文
FITOTERAPIA, 2020, 卷号: 140, 页码: 6
作者:  Jin, Qiong;  Wei, Xin;  Qin, Xu-Jie;  Gao, Fei;  Zhu, Pei-Feng;  Yuan, Hai-Lian;  Njateng, Guy Sedar Singor;  Dai, Zhi;  Liu, Ya-Ping;  Luo, Xiao-Dong
收藏  |  浏览/下载:130/0  |  提交时间:2020/03/24
seco-aporphine derivatives  Immunosuppressive bioactivity  Thalictrum wangii  
Antitumor pyridine alkaloids hybrid with diverse units from Alangium chinense 期刊论文
TETRAHEDRON LETTERS, 2020
作者:  Wei, Xin;  Yang, Jing;  Dai, Zhi;  Yu, Hao-Fei;  Ding, Cai-Feng;  Khan, Afsar;  Zhao, Yun-Li;  Liu, Ya-Ping;  Luo, Xiao-Dong
浏览  |  Adobe PDF(977Kb)  |  收藏  |  浏览/下载:117/40  |  提交时间:2021/01/05
Bioassay-guided isolation of anti-inflammatory diterpenoids with highly oxygenated substituents from kidney tea (Clerodendranthus spicatus) 期刊论文
JOURNAL OF FOOD BIOCHEMISTRY, 2020
作者:  Chen, Wei-Di;  Zhao, Yun-Li;  Dai, Zhi;  Zhou, Zhong-Shun;  Zhu, Pei-Feng;  Liu, Ya-Ping;  Zhao, Li-Xing;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1146Kb)  |  收藏  |  浏览/下载:146/48  |  提交时间:2021/01/05
Cytotoxic androstane derivatives from Sarcococca ruscifolia 期刊论文
FITOTERAPIA, 2020
作者:  Yi, Xin;  Dai, Zhi;  Xie, Tian-Zhen;  Xiao, Xia;  Liu, Ya-Ping;  Zhao, Li-Xing;  Yang, Xing-Wei;  Luo, Xiao-Dong
浏览  |  Adobe PDF(822Kb)  |  收藏  |  浏览/下载:120/51  |  提交时间:2021/01/05
Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 19, 页码: 3428-3434
作者:  Ding, Cai-Feng;  Zhang, Rong-Ping;  Yu, Hao-Fei;  Yang, Jing;  Qin, Xu-Jie;  Dai, Zhi;  Liu, Ya-Ping;  Lu, Qiu-Min;  Lai, Ren;  Luo, Xiao-Dong
浏览  |  Adobe PDF(2565Kb)  |  收藏  |  浏览/下载:223/34  |  提交时间:2019/11/07