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Cytotoxic phenolic constituents from Hypericum japonicum 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 33-40
作者:  Zhu, Wei;  Qiu, Jie;  Zeng, Yan-Rong;  Yi, Ping;  Lou, Hua-Yong;  Jian, Jun-You;  Zuo, Ming-Xing;  Duan, Lian;  Gu, Wei;  Huang, Lie-Jun;  Li, Yan-Mei;  Yuan, Chun-Mao;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(902Kb)  |  收藏  |  浏览/下载：381/171  |  提交时间：2019/09/10
Hypericum japonicum thunb. (Hypericaceae)  Phenolic compounds  Xanthone and flavonoid derivatives  Cytotoxic activities  Structure-activity relationship  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：312/37  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
浏览  |  Adobe PDF(2055Kb)  |  收藏  |  浏览/下载：268/37  |  提交时间：2019/04/15
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：280/47  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 1
作者:  Yuan, Wen-Juan;  Ding, Xiao;  Wang, Zhe;  Yang, Bi-Juan;  Li, Xiao-Nian;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Chen, Quan;  Di, Ying-Tong;  Aisa, Haji Akber;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3375Kb)  |  收藏  |  浏览/下载：285/53  |  提交时间：2017/12/18
Meroterpenoids with Antitumor Activities from Guava (Psidium guajava) 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017, 卷号: 65, 期号: 24, 页码: 4993-4999
作者:  Qin, Xu-Jie;  Yu, Qian;  Yan, Huan;  Khan, Afsar;  Feng, Mi-Yan;  Li, Pan-Pan;  Hao, Xiao-Jiang;  An, Lin-Kun;  Liu, Hai-Yang
浏览  |  Adobe PDF(3439Kb)  |  收藏  |  浏览/下载：281/86  |  提交时间：2017/07/31
Guava  Meroterpenoids  Cytotoxicity  Dna Topoisomerase i Inhibitors  Antiproliferative Activity  
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
作者:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(3775Kb)  |  收藏  |  浏览/下载：143/37  |  提交时间：2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 10, 页码: 1617
作者:  Hong, Ming;  Zhang, Yongsheng;  Li, Sha;  Tan, Hor Yue;  Wang, Ning;  Mu, Shuzhen;  Hao, Xiaojiang;  Feng, Yibin
浏览  |  Adobe PDF(92Kb)  |  收藏  |  浏览/下载：171/68  |  提交时间：2018/05/08
Wuweizi  Network Pharmacology  Hepatoprotective Effect  
Garmultins A-G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 22, 页码: 5904-5907
作者:  Tian, Dong Song;  Yi, Ping;  Xia, Lei;  Xiao, Xin;  Fan, Yi Min;  Gu, Wei;  Huang, Lie Jun;  Ben-David, Yaacov;  Di, Ying Tong;  Yuan, Chun Mao;  Hao, Xiao Jiang
Adobe PDF(1168Kb)  |  收藏  |  浏览/下载：356/71  |  提交时间：2017/01/05
Synthesis, Neuro-protection and Anti-cancer Activities of Simple Isatin Mannich and Schiff Bases 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2016, 卷号: 13, 期号: 5, 页码: 395-400
作者:  Chen, Gang;  Ning, Yang;  Zhao, Wei;  Zhang, Yanqiu;  Zhang, Yu;  Hao, Xiaojiang;  Wang, Ye;  Mu, Shuzhen
浏览  |  Adobe PDF(1361Kb)  |  收藏  |  浏览/下载：229/70  |  提交时间：2016/08/22
Isatin  Mannich Base  Schiff Base  Synthesis  Neuro-protection  Anti-tumor