Garmultins A-G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora
Tian, Dong Song1,2,4; Yi, Ping1,2; Xia, Lei1,2; Xiao, Xin4; Fan, Yi Min1,2; Gu, Wei1,2; Huang, Lie Jun1,2; Ben-David, Yaacov1,2; Di, Ying Tong3; Yuan, Chun Mao1,2; Hao, Xiao Jiang1,2,3
2016-11-18
发表期刊ORGANIC LETTERS
卷号18期号:22页码:5904-5907
摘要Garmultins A and B (1 and 2), two polycyclic polyprenylated acylphloroglucinols characterized by the coupling of two novel cages, 2,11-dioxatricyclo [4.4.1.0(3,9)]undecane and tricydo[4.3.1.0(3,7)]decane, along with five biogenetically related analogues (3-7), were isolated from Garcinia multiflora. Their structures and absolute configurations were determined by extensive NMR analysis, X-ray crystallography, and electronic circular dichroism calculations. Three compounds were capable of inhibiting oncogene expression and inducing apoptosis in human erythroleukemia cells.
资助信息National Natural Science Foundation of China(81502959); Natural Science Foundation of Guizhou(QKH J-2015-2106); 100 Leading Talents of Guizhou Province; science and technology project of Guizhou(QKHT Z-2014-4007)
DOI10.1021/acs.orglett.6b03004
收录类别SCI
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000388428600034
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被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/33675
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Peoples R China
2.Chinese Acad Sci, Guiyang 550002, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
4.Guizhou Univ, Guiyang 550025, Peoples R China
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Tian, Dong Song,Yi, Ping,Xia, Lei,et al. Garmultins A-G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora[J]. ORGANIC LETTERS,2016,18(22):5904-5907.
APA Tian, Dong Song.,Yi, Ping.,Xia, Lei.,Xiao, Xin.,Fan, Yi Min.,...&Hao, Xiao Jiang.(2016).Garmultins A-G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora.ORGANIC LETTERS,18(22),5904-5907.
MLA Tian, Dong Song,et al."Garmultins A-G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora".ORGANIC LETTERS 18.22(2016):5904-5907.
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