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Branched Chondroitin Sulfate Oligosaccharides Derived from the Sea Cucumber Acaudina molpadioides Stimulate Neurite Outgrowth 期刊论文
MARINE DRUGS, 2022, 卷号: 20, 期号: 10, 页码: 653
作者:  Wang, Weili;  Mao, Hui;  Li, Sujuan;  Zhang, Longlong;  Yang, Lian;  Yin, Ronghua;  Zhao, Jinhua
浏览  |  Adobe PDF(5142Kb)  |  收藏  |  浏览/下载：9/2  |  提交时间：2024/04/30
fucosylated chondroitin sulfate  sea cucumber  disaccharide branch  oligosaccharide  neurite outgrowth  stimulation  HIPPOCAMPAL-NEURONS  PROMOTING ACTIVITY  GLYCOSAMINOGLYCAN  DISACCHARIDE  INHIBITOR  
Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118290
作者:  Li,Shanni;  Zhong,Wei;  Pan,Ying;  Lin,Lisha;  Cai,Ying;  Mao,Hui;  Zhang,Taocui;  Li,Sujuan;  Chen,Ru;  Zhou,Lutan;  Wang,Weili;  Cui,Qinghua;  Yin,Ronghua;  Huang,Shengxiong;  Zhao,Jinhua
浏览  |  Adobe PDF(2581Kb)  |  收藏  |  浏览/下载：179/19  |  提交时间：2022/04/02
Disaccharide branch  Fucosylated glycosaminoglycan  Holothuria nobilis  Oligosaccharide  Anticoagulant  INTRINSIC TENASE COMPLEX  CHONDROITIN SULFATE  ACAUDINA-MOLPADIOIDEA  FACTOR XASE  HEPARIN  DEPOLYMERIZATION  OLIGOSACCHARIDES  POLYSACCHARIDES  DERIVATIVES  
Structural characterization of oligosaccharides from free radical depolymerized fucosylated glycosaminoglycan and suggested mechanism of depolymerization 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 270, 页码: 118368
作者:  Chen,Ru;  Yin,Ronghua;  Li,Shanni;  Pan,Ying;  Mao,Hui;  Cai,Ying;  Lin,Lisha;  Wang,Weili;  Zhang,Taocui;  Zhou,Lutan;  Gao,Na;  Luo,Xiaodong;  Zhao,Jinhua
浏览  |  Adobe PDF(3356Kb)  |  收藏  |  浏览/下载：89/22  |  提交时间：2022/04/02
Fucosylated glycosaminoglycan  Free radical depolymerization  Chemical structure  Oligosaccharide  NMR  INTRINSIC TENASE COMPLEX  ANTICOAGULANT ACTIVITIES  SEA-CUCUMBER  CHONDROITIN SULFATE  PHYSICOCHEMICAL CHARACTERISTICS  FACTOR XASE  POLYSACCHARIDES  DERIVATIVES  HEPARIN  
Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats by Bioanalytical Methods 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 4, 页码: 212
作者:  Liu,Shuang;  Zhang,Taocui;  Sun,Huifang;  Lin,Lisha;  Gao,Na;  Wang,Weili;  Li,Sujuan;  Zhao,Jinhua
浏览  |  Adobe PDF(1230Kb)  |  收藏  |  浏览/下载：154/53  |  提交时间：2022/04/02
pharmacokinetics  pharmacodynamics  anticoagulant  fucosylated glycosaminoglycan  dHG-5  method validation  
High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on alpha(IIb)beta(3) and platelet secretion 期刊论文
PLATELETS, 2021, 卷号: 32, 期号: 7, 页码: 975-983
作者:  Lin,Lisha;  Yang,Lian;  Chen,Jun;  Zhou,Lutan;  Li,Sujuan;  Gao,Na;  Zhao,Jinhua
浏览  |  Adobe PDF(3733Kb)  |  收藏  |  浏览/下载：60/16  |  提交时间：2022/04/02
Aggregation  fucosylated glycosaminoglycan  human platelets  secretion  alpha(IIb beta 3)  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  INTEGRIN ALPHA(IIB)BETA(3)  ACTIVATION  AGGLUTINATION  RECEPTOR  ADP  INHIBITION  GENERATION  MECHANISM  
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives 期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
作者:  Yin,Ronghua;  Zhou,Lutan;  Gao,Na;  Lin,Lisha;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Zuo,Zhili;  Hu,Kaifeng;  Huang,Shengxiong;  Liu,Jikai;  Zhao,Jinhua
浏览  |  Adobe PDF(4401Kb)  |  收藏  |  浏览/下载：109/25  |  提交时间：2022/04/02
FUCOSYLATED CHONDROITIN SULFATE  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  SEA-CUCUMBER  FUCOSE BRANCHES  BODY-WALL  INDEPENDENT INHIBITION  POLYSACCHARIDE ACCOUNT  FACTOR XASE  HEPARIN  
Effects of Native Fucosylated Glycosaminoglycan, Its Depolymerized Derivatives on Intrinsic Factor Xase, Coagulation, Thrombosis, and Hemorrhagic Risk 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2020
作者:  Zhou, Lutan;  Gao, Na;  Sun, Huifang;  Xiao, Chuang;  Yang, Lian;  Lin, Lisha;  Yin, Ronghua;  Li, Zi;  Zhang, Hongbin;  Ji, Xu;  Zhao, Jinhua
浏览  |  Adobe PDF(1210Kb)  |  收藏  |  浏览/下载：222/53  |  提交时间：2021/01/05
From multi-target anticoagulants to DOACs, and intrinsic coagulation factor inhibitors 期刊论文
BLOOD REVIEWS, 2020
作者:  Lin, Lisha;  Zhao, Longyan;  Gao, Na;  Yin, Ronghua;  Li, Sujuan;  Sun, Huifang;  Zhou, Lutan;  Zhao, Guiling;  Purcell, Steven W.;  Zhao, Jinhua
浏览  |  Adobe PDF(943Kb)  |  收藏  |  浏览/下载：101/25  |  提交时间：2021/01/05
A new fucosylated glycosaminoglycan containing disaccharide branches from Acaudina molpadioides: Unusual structure and anti-intrinsic tenase activity 期刊论文
CARBOHYDRATE POLYMERS, 2020
作者:  Mao, Hui;  Cai, Ying;  Li, Shanni;  Sun, Huifang;  Lin, Lisha;  Pan, Ying;  Yang, Wenjiao;  He, Zhicheng;  Chen, Ru;  Zhou, Lutan;  Wang, Weili;  Yin, Ronghua;  Zhao, Jinhua
浏览  |  Adobe PDF(2623Kb)  |  收藏  |  浏览/下载：102/20  |  提交时间：2021/01/05
Characterization of the Hydrolysis Kinetics of Fucosylated Glycosaminoglycan in Mild Acid and Structures of the Resulting Oligosaccharides 期刊论文
MARINE DRUGS, 2020
作者:  Liu, Xixi;  Zhang, Zhexian;  Mao, Hui;  Wang, Pin;  Zuo, Zhichuang;  Gao, Li;  Shi, Xiang;  Yin, Ronghua;  Gao, Na;  Zhao, Jinhua
浏览  |  Adobe PDF(1321Kb)  |  收藏  |  浏览/下载：137/45  |  提交时间：2021/01/05