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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：249/70  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Aurovertin B sensitizes colorectal cancer cells to NK cell recognition and lysis 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 503, 期号: 4, 页码: 3057-3063
作者:  Zhu, Huifang;  Wang, Fei;  Ju, Xiaoman;  Kong, Lingmei;  An, Tao;  Zhao, Zhangxun;  Liu, Jikai;  Li, Yan
收藏  |  浏览/下载：436/0  |  提交时间：2018/10/22
Aurovertin B  Cytotoxicity  Immunotherapy  NK cell  NKG2D ligands  
Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 17, 页码: 10158-10165
作者:  Zhang, Shuaibing;  Huang, Ying;  He, Shijun;  Chen, Heping;  Wu, Bin;  Li, Shanyong;  Zhao, Zhenzhu;  Li, Zhenghui;  Wang, Xian;  Zuo, Jianping;  Feng, Tao;  Liu, Jikai
收藏  |  浏览/下载：132/0  |  提交时间：2018/10/22
Digestibility of fucosylated glycosaminoglycan from sea cucumber and its effects on digestive enzymes under simulated salivary and gastrointestinal conditions 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 186, 页码: 217-225
作者:  Zhao, Longyan;  Qin, Yujing;  Guan, Ruowei;  Zheng, Wenqi;  Liu, Jikai;  Zhao, Jinhua
收藏  |  浏览/下载：159/0  |  提交时间：2018/05/08
Sea Cucumber  Polysaccharide  Fucosylated Glycosaminoglycan  In Vitro Digestion  Digestive Enzyme  
Enzyme-Assisted Extraction Optimization, Characterization and Antioxidant Activity of Polysaccharides from Sea Cucumber Phyllophorus proteus 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 590
作者:  Qin, Yujing;  Yuan, Qingxia;  Zhang, Yuexing;  Li, Jialu;  Zhu, Xinjiao;  Zhao, Lingling;  Wen, Jing;  Liu, Jikai;  Zhao, Longyan;  Zhao, Jinhua
浏览  |  Adobe PDF(5270Kb)  |  收藏  |  浏览/下载：283/75  |  提交时间：2018/07/02
Sea Cucumber  Polysaccharide  Enzyme-assisted Extraction  Characterization  Antioxidant Activity  
Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
作者:  Xu, Yuhui;  Niu, Yanfen;  Gao, Yuan;  Wang, Fang;  Qin, Wanying;  Lu, Yanting;  Hu, Jing;  Peng, Li;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4940Kb)  |  收藏  |  浏览/下载：375/61  |  提交时间：2017/10/23
Insulin-resistance  Tuberculata Beumee  Metabolic Syndrome  Srebp  Liver  Cholesterol  Constituents  Homeostasis  Inhibition  Receptors  
Neoalbaconol inhibits angiogenesis and tumor growth by suppressing EGFR-mediated VEGF production 期刊论文
MOLECULAR CARCINOGENESIS, 2017, 卷号: 56, 期号: 5, 页码: 1414-1426
作者:  Yu, Xinfang;  Li, Wei;  Deng, Qipan;  You, Shuo;  Liu, Haidan;  Peng, Songling;  Liu, Xiaolan;  Lu, Jingchen;  Luo, Xiangjian;  Yang, Lifang;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Liu, Wenbin;  Wu, Shengqi;  Ding, Zhihui;  Feng, Tao;  Zhou, Jian;  Fan, Jia;  Bode, Ann M.;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
浏览  |  Adobe PDF(6365Kb)  |  收藏  |  浏览/下载：364/115  |  提交时间：2017/06/30
Angiogenesis  Breast Cancer  Egfr  Neoalbaconol  Vegf  
A New Sesquiterpene from the Endophytic Fungus Nigrospora sphaerica #003 期刊论文
RECORDS OF NATURAL PRODUCTS, 2016, 卷号: 10, 期号: 3, 页码: 307-310
作者:  Chen, Ziming;  Dong, Zejun;  Wen, Jing;  Feng, Tao;  Liu, Jikai
浏览  |  Adobe PDF(1343Kb)  |  收藏  |  浏览/下载：278/79  |  提交时间：2016/08/22
Endophytic Fungus  Nigrospora Sphaerica  Sesquiterpene  
Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 40, 页码: 42704-42716
作者:  Luo, Xiangjian;  Yang, Lifang;  Xiao, Lanbo;  Xia, Xiaofeng;  Dong, Xin;  Zhong, Juanfang;  Liu, Ying;  Li, Namei;  Chen, Ling;  Li, Hongde;  Li, Wei;  Liu, Wenbin;  Yu, Xinfang;  Chen, Hanyong;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Bode, Ann;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
浏览  |  Adobe PDF(5262Kb)  |  收藏  |  浏览/下载：224/36  |  提交时间：2016/06/27
Grifolin  Erk1/2  Dnmt1  Metastasis  
The role of targeting kinase activity by natural products in cancer chemoprevention and chemotherapy (Review) 期刊论文
ONCOLOGY REPORTS, 2015, 卷号: 34, 期号: 2, 页码: 547-554
作者:  Luo, Xiangjian;  Yu, Xinfang;  Liu, Sufang;  Deng, Qipan;  Liu, Xiaolan;  Peng, Songling;  Li, Hongde;  Liu, Jikai;  Cao, Ya
浏览  |  Adobe PDF(755Kb)  |  收藏  |  浏览/下载：358/173  |  提交时间：2015/12/17
Natural Products  Grifolin  Neoalbaconol  Epigallocatechin-3-gallate  Cancer Prevention