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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  Favorite  |  View/Download：317/1  |  Submit date：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines 期刊论文
出版物, 3111, 期号: 0, 页码: 1—28
Authors:  Ming-Ju Hsieh;  Chiao-Wen Lin;  Shun-Fa Yang;  Mu-Kuan Chen;  Hui-Ling Chiou
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Glabridin  Migration  Invasion  Matrix Metalloproteinase-9  Hepatoma  
Structurally diverse spirocyclic polycyclic polyprenylated acylphloroglucinols from Hypericum ascyron Linn. and their anti-tumor activity 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 212, 页码: 113727
Authors:  Hu,Ya-Li;  Yue,Grace Gar-Lee;  Li,Xing-Ren;  Xu,Gang;  Lau,Clara Bik-San
View  |  Adobe PDF(6872Kb)  |  Favorite  |  View/Download：22/12  |  Submit date：2024/07/25
Hypericaceae  Polycyclic polyprenylated acylphloroglucinols  Spirocyclic polyprenylated acylphloroglucinols  HCT116 cells  Zebrafish model  Hypericum ascyron Linn  NATURAL-PRODUCTS  A-H  DERIVATIVES  FLOWERS  VEGF  
Canthin-6-one ameliorates TNBS-induced colitis in rats by modulating inflammation and oxidative stress. An in vivo and in silico approach 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 186, 页码: 114490
Authors:  Arunachalam,Karuppusamy;  Damazo,Amilcar Sabino;  Macho,Antonio;  Matchado,Monica Steffi;  Pavan,Eduarda;  Figueiredo,Fabiana de Freitas;  Oliveira,Darley Maria;  Duckworth,Carrie A.;  Thangaraj,Parimelazhagan;  Leonti,Marco;  de Oliveira Martins,Domingos Tabajara
Favorite  |  View/Download：58/0  |  Submit date：2022/04/02
Canthin-6-one  Inflammatory bowel disease  TNBS  Cytokines  Colitis  BOWEL-DISEASE  PROINFLAMMATORY CYTOKINES  CLINICAL-ASPECTS  ACTIVITY SPECTRA  PATHOGENESIS  DOCKING  CELLS  ACCUMULATION  PREDICTION  MODEL  
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
Authors:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
View  |  Adobe PDF(8744Kb)  |  Favorite  |  View/Download：145/53  |  Submit date：2022/04/02
Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
Milk Exosomes Transfer Oligosaccharides into Macrophages to Modulate Immunity and Attenuate Adherent-Invasive E. coli (AIEC) Infection 期刊论文
NUTRIENTS, 2021, 卷号: 13, 期号: 9, 页码: 3198
Authors:  He,Yingying;  He,Zhicheng;  Leone,Serena;  Liu,Shubai
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HMOs  exosome  mucosal immunity  2 '-FL  macrophages  INTESTINAL HOMEOSTASIS  MECHANISM  VESICLES  RECEPTOR  CELLS  
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects? 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
Authors:  Gou,Leilei;  Yue,Grace Gar-Lee;  Puno,Pema Tenzin;  Lau,Clara Bik-San
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Breast cancer  Mast cell  Macrophage  Natural products  Herbs  Extracts  TUMOR-ASSOCIATED MACROPHAGES  NF-KAPPA-B  MEDIATED ALLERGIC REACTIONS  PRO-INFLAMMATORY CYTOKINES  ANTIINFLAMMATORY ACTIVITY  ATOPIC-DERMATITIS  UMBROSA ROOT  TNF-ALPHA  IN-VIVO  C-KIT  
Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 166, 页码: 105527
Authors:  Zhou,Lutan;  Yin,Ronghua;  Gao,Na;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Ren,Lin;  Yang,Lian;  Zuo,Zhili;  Zhang,Hongbin;  Zhao,Jinhua
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Oligosaccharides  Heparanase  Angiogenesis  Metastasis  FIBROBLAST-GROWTH-FACTOR  TUMOR-GROWTH  SULFATE PROTEOGLYCANS  MAMMALIAN HEPARANASE  COMBINATION  MECHANISMS  DISCOVERY  BINDING  TARGET  PI-88  
Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans 期刊论文
CELL CALCIUM, 2021, 卷号: 93, 页码: 102327
Authors:  Yang,Zhong-Lin;  Chen,Jian-Ning;  Lu,Yu-Yang;  Lu,Min;  Wan,Qin-Li;  Wu,Gui-Sheng;  Luo,Huai-Rong
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Inositol polyphosphates  Inositol polyphosphate multikinase  Type I inositol 5-phosphatase  Development  Calcium signaling  Defecation rhythm  C. elegans  C-ELEGANS  PHOSPHOLIPASE-C  CALCIUM  1,4,5-TRISPHOSPHATE  CALCINEURIN  KINASE  IDENTIFICATION  TRISPHOSPHATE  METABOLISM  RECEPTOR  
Traditional Chinese medicine compound, Bu Sheng Hui Yang Fang, promotes the proliferation of lymphocytes in the immunosuppressed mice potentially by upregulating IL-4 signaling 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 134, 页码: 111107
Authors:  Wang,Yajie;  Tan,Jiabin;  Hu,Peng;  Pei,Qiang;  Wen,Yan;  Ma,Wenqing;  Shi,Keqian;  Li,Zengzheng;  Li,Huiyuan;  Cheng,Fengyu;  Gu,Xuezhong;  Yao,Xiangmei;  Man,Yan;  Zhao,Renbin;  Feng,Shuai;  Ding,Xiao;  Yang,Tonghua
View  |  Adobe PDF(7551Kb)  |  Favorite  |  View/Download：106/29  |  Submit date：2022/04/02
Bu Shen Hui Yang Fang (BSHY)  Immunoenhancement  Lymphocytes  Proliferation  Cytokine  IL-4  ACUTE MYELOID-LEUKEMIA  IMMUNE-SYSTEM  CANCER  CELLS  IMMUNOSURVEILLANCE  EXPRESSION