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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：331/41  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：312/67  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：299/50  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Leucoflavonine, a new bioactive racemic flavoalkaloid from the leaves of Leucosceptrum canum 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 2, 页码: 442-446
作者:  Feng, Ling;  Zhang, Yu;  Liu, Yan-Chun;  Liu, Yan;  Luo, Shi-Hong;  Huang, Chun-Shuai;  Li, Sheng-Hong
Adobe PDF(1106Kb)  |  收藏  |  浏览/下载：186/33  |  提交时间：2019/03/18
Leucosceptrum canum  Lamiaceae  Flavoalkaloid  Leucoflavonine  Biological activities  
Cytotoxic Effects of Compounds Isolated from Ricinodendron heudelotii 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 11
作者:  Yakubu, Omolara F.;  Adebayo, Abiodun H.;  Dokunmu, Titilope M.;  Zhang, Ying-Jun;  Iweala, Emeka E. J.
Adobe PDF(1826Kb)  |  收藏  |  浏览/下载：214/45  |  提交时间：2019/03/18
anticancer  Ricinodendron heudelotii  chemoprevention  
Diversified abietane family diterpenoids from the leaves of Leucosceptrurn canum and their cytotoxic activity 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 157, 页码: 43-52
作者:  Guo, Kai;  Liu, Yan-Chun;  Liu, Yan;  Luo, Shi-Hong;  Li, Wen-Yuan;  Li, Xiao-Nian;  Li, Sheng-Hong
Adobe PDF(3814Kb)  |  收藏  |  浏览/下载：241/46  |  提交时间：2019/03/18
Leucosceptrum canum  Lamiaceae  Diterpenoids  Abietane family  Cytotoxic activity  
Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 9
作者:  Hu, Yu;  Li, Xiao-Nian;  Ma, Ze-Jin;  Puno, Pema-Tenzin;  Zhao, Yong;  Zhao, Yan;  Xiao, Ye-Zhi;  Zhang, Wei;  Liu, Jing-Ping
收藏  |  浏览/下载：164/0  |  提交时间：2019/03/18
ent-kaurane-type diterpenoid derivatives  antitumor  synthesis  
Seeing the light: Shifting from wild rhizomes to extraction of active ingredients from above-ground parts of Paris polyphylla var. yunnanensis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 224, 期号: 1, 页码: 134-139
作者:  Qin, Xu-Jie;  Ni, Wei;  Chen, Chang-Xiang;  Liu, Hai-Yang
Adobe PDF(944Kb)  |  收藏  |  浏览/下载：297/90  |  提交时间：2018/09/27
Paris Polyphylla Var. Yunnanensis  Rhizoma Paridis  Steroidal Saponins  Sustainable Utilization  
Cytotoxicity-Guided Isolation of Two New Phenolic Derivatives from Dryopteris fragrans (L.) Schott 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 7, 页码: 11
作者:  Zhang, Tong;  Wang, Li;  Duan, De-Hua;  Zhang, Yi-Hao;  Huang, Sheng-Xiong;  Chang, Ying
收藏  |  浏览/下载：136/0  |  提交时间：2018/11/12
cytotoxicity-guided  phenolic derivatives  Dryopteris fragrans  chemical derivatization  immuno-regulation activity