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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:
Zhu,Yan-Yan
;
Jin,Qiong
;
Chen,Shan-Shan
;
Jin,Dan-Ni
;
Wang,Zhao-Jie
;
He,Ying-Jie
;
Chen,Hui-Cheng
;
Zhao,Yun-Li
;
Zhao,Li-Xing
;
Dai,Zhi
;
Luo,Xiao-Dong
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浏览/下载:225/51
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提交时间:2022/04/02
Neothalfine
Bisbenzylisoquinoline alkaloid
Metastatic colorectal cancer
Metabolomic
Mitochondrial apoptosis
SMALL MOLECULES
IRINOTECAN
RESISTANCE
CELL
IMMUNOTHERAPY
OPPORTUNITIES
CHEMOTHERAPY
VINORELBINE
ALKALOIDS
PATHWAY
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations
期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:
Peng,Wan
;
Dai,Man-Yun
;
Bao,Li-Juan
;
Zhu,Wei-Feng
;
Li,Fei
Adobe PDF(2010Kb)
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浏览/下载:135/18
  |  
提交时间:2022/04/02
Tripterygium wilfordii
liver injury
farnesoid X receptor
bile acid metabolism
metabolomics
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Li,Tian-Ze
;
Hu,Jing
;
Huang,Xiao-Yan
;
Zhang,Xue-Mei
;
Guo,Yuan-Qiang
;
Geng,Chang-An
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浏览/下载:150/63
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提交时间:2022/04/02
Alpinia katsumadai
Katsumadainols B-1-B-15
Natural products
Structure elucidation
Biological activity
TYROSINE-PHOSPHATASE 1B
GLYCOGEN-PHOSPHORYLASE
ALPHA-GLUCOSIDASE
ABSOLUTE-CONFIGURATION
STRUCTURE ELUCIDATION
DUAL INHIBITION
SEEDS
CONSTITUENT
DERIVATIVES
CHALCONE
Hypermonones A-I, New Polyprenylated Acylphloroglucinols from Hypericum monogynum with Multidrug Resistance Reversal Activity
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 9, 页码: 2422-2432
作者:
Zeng,Yan-Rong
;
Li,Ya-Nan
;
Yang,Jue
;
Yi,Ping
;
Huang,Lei
;
Huang,Lie-Jun
;
Gu,Wei
;
Hu,Zhan-Xing
;
Li,Yan-Mei
;
Yuan,Chun-Mao
;
Hao,Xiao-Jiang
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浏览/下载:103/30
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提交时间:2022/04/02
Hypericum monogynum
Phytochemistry
Structure elucidation
Biological activity
Multidrug resistance reversal activity
P-GLYCOPROTEIN
MODULATORS
CANCER
Fungal succession in decomposing woody debris across a tropical forest disturbance gradient
期刊论文
SOIL BIOLOGY & BIOCHEMISTRY, 2021, 卷号: 155, 页码: 108142
作者:
Dossa,Gbadamassi G. O.
;
Yang,Yun-Qiang
;
Hu,Weiming
;
Paudel,Ekananda
;
Schaefer,Douglas
;
Yang,Yong-Ping
;
Cao,Kun-Fang
;
Xu,Jian-Chu
;
Bushley,Kathryn E.
;
Harrison,Rhett D.
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Adobe PDF(6343Kb)
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浏览/下载:107/13
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提交时间:2022/04/02
Carbon cycle
Coarse woody debris
Decomposition
Fungi
Ecosystem function
Landscape
Tropical forest
Wood density
INHABITING FUNGI
DECAY
DIVERSITY
BARK
COMMUNITIES
TERMITES
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors
期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Huang,Xiao-Yan
;
Hu,Jing
;
Zhang,Xu-Ke
;
Guo,Yuan-Qiang
;
Zhang,Xue-Mei
;
Geng,Chang-An
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Adobe PDF(5184Kb)
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浏览/下载:104/30
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提交时间:2022/04/02
Amomum tsao-ko
Amomutsaokins A-H
Flavanol-menthane conjugates
PTP1B selective inhibitors
alpha-Glucosidase inhibitors
ANTIOXIDANT ACTIVITY
ESSENTIAL OIL
CONSTITUENTS
TANNINS
CREVOST
ACID
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
作者:
Hu,Mi
;
Varier,Krishnapriya M.
;
Li,Zhicao
;
Qin,Xujie
;
Rao,Qing
;
Song,Jingrui
;
Hu,Anling
;
Hang,Yubing
;
Yuan,Chunmao
;
Gajendran,Babu
;
Shu,Liping
;
Wen,Min
;
Li,Yanmei
;
Liu,Haiyang
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浏览/下载:123/44
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提交时间:2022/04/02
Acylphloroglucinol
HEL cells
Intrinsic apoptotic pathway
Anti-angiogenesis
STAT3
Flk-1
CALLISTEMON-CITRINUS
TUMOR ANGIOGENESIS
DNA
DERIVATIVES
ANTICANCER
APOPTOSIS
ACTIVATION
INHIBITORS
TARGETS
LEAVES
Targeting ubiquitin conjugating enzyme UbcH5b by a triterpenoid PC3-15 from Schisandra plants sensitizes triple-negative breast cancer cells to lapatinib
期刊论文
CANCER LETTERS, 2021, 卷号: 504, 页码: 125-136
作者:
Huang,Maobo
;
Zhou,Yuanfei
;
Duan,Dongzhu
;
Yang,Chuanyu
;
Zhou,Zhongmei
;
Li,Fubing
;
Kong,Yanjie
;
Hsieh,Yi-Ching
;
Zhang,Ruihan
;
Ding,Wenping
;
Xiao,Weilie
;
Puno,PemaTenzin
;
Chen,Ceshi
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Adobe PDF(9762Kb)
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浏览/下载:107/23
  |  
提交时间:2022/04/02
HECTD3
UbcH5b
Ubiquitination
Autophagy
Schisandraceae triterpenoid
Musarin, a novel protein with tyrosine kinase inhibitory activity from Trametes versicolor, accepted inhibits colorectal cancer stem cell growth
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 144, 页码: 112339
作者:
He,YingYing
;
Liu,Shubai
;
Newburg,David S.
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浏览/下载:133/25
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提交时间:2022/04/02
Trametes versicolor
Cancer stem cell
Tyrosine kinase inhibitor
EGFR
Colorectal cancer
FACTOR RECEPTOR
POLYSACCHAROPEPTIDE
RESISTANCE
TARGET
EGFR
TOOL
PSP
DNA
Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway
期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
作者:
Yang,Hao-Jie
;
Li,Ya-Nan
;
Yan,Chen
;
Yang,Jue
;
Zeng,Yan-Rong
;
Yi,Ping
;
Li,Yan-Mei
;
Hao,Xiao-Jiang
;
Yuan,Chun-Mao
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Adobe PDF(2804Kb)
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浏览/下载:99/28
  |  
提交时间:2022/04/02
Dysoxylum gotadhora
Rocaglaol derivatives
HCT116
Cytotoxic activity
MAPK pathway
FLAVAGLINES