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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
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Abt-263  Sorafenib  Combination Therapy  Cancer  
Identification of limonoids from Walsura yunnanensis and evaluation of their cytotoxicity against cancer cell lines 期刊论文
Fitoterapia, 2022
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Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 卷号: 17, 期号: 11, 页码: 2703-2717
Authors:  Wei,Ruiran;  Zhao,Yueqin;  Wang,Juan;  Yang,Xu;  Li,Shunlin;  Wang,Yinyuan;  Yang,Xingzhi;  Fei,Jimin;  Hao,Xiaojiang;  Zhao,Yuhan;  Gui,Liming;  Ding,Xiao
Favorite  |  View/Download：29/0  |  Submit date：2022/04/02
ferroptosis  tagitinin C  ROS  ER stress  Nrf2-HO-1 pathway  ENDOPLASMIC-RETICULUM STRESS  ER-STRESS  OXIDATIVE STRESS  TUMOR-SUPPRESSOR  NRF2  DEATH  IRON  DIFFERENTIATION  MECHANISMS  RESISTANCE  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
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Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Antimicrobial Peptide Brevivin-1RL1 from Frog Skin Secretion Induces Apoptosis and Necrosis of Tumor Cells 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 7, 页码: 2059
Authors:  Ju,Xiaoman;  Fan,Dongmei;  Kong,Lingmei;  Yang,Qihong;  Zhu,Yiying;  Zhang,Shaohua;  Su,Guifeng;  Li,Yan
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antimicrobial peptide  Brevivin-1RL1  apoptosis  necrosis  caspase  anticancer  BULLFROG  PHOSPHATIDYLSERINE  MECHANISMS  ANTITUMOR  SURFACE  
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
Authors:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
View  |  Adobe PDF(8744Kb)  |  Favorite  |  View/Download：19/0  |  Submit date：2022/04/02
Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
Musarin, a novel protein with tyrosine kinase inhibitory activity from Trametes versicolor, accepted inhibits colorectal cancer stem cell growth 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 144, 页码: 112339
Authors:  He,YingYing;  Liu,Shubai;  Newburg,David S.
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Trametes versicolor  Cancer stem cell  Tyrosine kinase inhibitor  EGFR  Colorectal cancer  FACTOR RECEPTOR  POLYSACCHAROPEPTIDE  RESISTANCE  TARGET  EGFR  TOOL  PSP  DNA  
Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway 期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
Authors:  Yang,Hao-Jie;  Li,Ya-Nan;  Yan,Chen;  Yang,Jue;  Zeng,Yan-Rong;  Yi,Ping;  Li,Yan-Mei;  Hao,Xiao-Jiang;  Yuan,Chun-Mao
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Dysoxylum gotadhora  Rocaglaol derivatives  HCT116  Cytotoxic activity  MAPK pathway  FLAVAGLINES  
Sesquiterpene lactones from Carpesium abrotanoides L. and their activity in inducing protective autophagy 期刊论文
NATURAL PRODUCT RESEARCH, 2021
Authors:  Yang,Bao-Jia;  Wang,Juan;  Zeng,Zheng-Quan;  Yang,Xu;  Huang,Ai-Ying;  Hao,Xiao-Jiang;  Ding,Xiao;  Li,Shun-Lin
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Carpesium abrotanoides L  sesquiterpene lactone  autophagy  lysosomal biogenesis  cytotoxic activity  
USP47 maintains the stemness of colorectal cancer cells and is inhibited by parthenolide 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 卷号: 562, 页码: 21-28
Authors:  Zhang,Shaohua;  Ju,Xiaoman;  Yang,Qihong;  Zhu,Yiying;  Fan,Dongmei;  Su,Guifeng;  Kong,Lingmei;  Li,Yan
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USP47  Cancer stem cell  Colorectal cancer  Parthenolide  Deubiquitinase  SESQUITERPENE LACTONE PARTHENOLIDE  DEUBIQUITINASES  STABILIZATION  LEUKEMIA