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Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：74/15  |  提交时间：2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 874474
作者:  Arunachalam, Karuppusamy;  Sreeja, Puthanpura Sasidharan;  Yang, Xuefei
浏览  |  Adobe PDF(2493Kb)  |  收藏  |  浏览/下载：31/8  |  提交时间：2024/08/21
reactive oxygen species  oxidative stress  antioxidant  diabetes mellitus  mushroom polysaccharides  AGARICUS-BLAZEI MURILL  GANODERMA-LUCIDUM POLYSACCHARIDES  ACTIVATED SIGNALING PATHWAYS  TYPE-2 DIABETES-MELLITUS  PROTEIN-KINASE-C  MT-ALPHA-GLUCAN  MEDICINAL MUSHROOM  SUBMERGED-CULTURE  PHELLINUS-LINTEUS  STRUCTURAL-CHARACTERIZATION  
Bitter Melon and Diabetes Mellitus 期刊论文
FOOD REVIEWS INTERNATIONAL, 2021
作者:  Gao,Ya;  Li,Xian;  Huang,Yanjie;  Chen,Jianchao;  Qiu,Minghua
收藏  |  浏览/下载：104/0  |  提交时间：2022/04/02
Bitter melon  diabetes mellitus  crude extracts  phyto-metabolites  hypoglycemic mechanism  MOMORDICA-CHARANTIA L.  11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1  ALPHA-GLUCOSIDASE INHIBITION  INSULIN-RESISTANCE  ANTIDIABETIC ACTIVITIES  GUT MICROBIOTA  STRUCTURAL-CHARACTERIZATION  PHENOLIC-COMPOUNDS  OXIDATIVE STRESS  PROTEIN-KINASE  
Neo-clerodane Diterpenoids with Hypoglycemic Effects in Vivo from the Aerial Parts of Salvia hispanica L. 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 9, 页码: e2100517
作者:  Fan,Min;  Wang,Ting;  Peng,Li-Yan;  Huang,Jun-Shang;  Wu,Xing-De;  Wang,He-Yao;  Zhao,Qin-Shi
浏览  |  Adobe PDF(1403Kb)  |  收藏  |  浏览/下载：236/39  |  提交时间：2022/04/02
Salvia hispanica  neo-clerodane diterpenoid  salvihispin H  type 2 diabetes mellitus  GLUCOSE-TOLERANCE  RISK-FACTORS  THERAPY  
Multiple in vitro biological effects of phenolic compounds from Terminalia chebula var. tomentella 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 275, 页码: 114135
作者:  Zhang,Xiao-Rui;  Qiao,Yi-Jun;  Zhu,Hong-Tao;  Kong,Qing-Hua;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
浏览  |  Adobe PDF(2686Kb)  |  收藏  |  浏览/下载：224/40  |  提交时间：2022/04/02
Terminalia chebula var  tomentella  Combretaceae  Fructus Chebulae  Hydrolyzed tannins  Simple phenolic compounds  Anti-inflammation  Anti-diabetes  NITRIC-OXIDE  ANTIOXIDANT  TANNINS  CONSTITUENTS  VALIDATION  ALGORITHM  ESTERS  FRUITS  
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：299/76  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
A review of the polysaccharide, protein and selected nutrient content of Auricularia, and their potential pharmacological value 期刊论文
MYCOSPHERE, 2019, 卷号: 10, 期号: 1, 页码: 579-607
作者:  Bandara, A. R.;  Rapior, S.;  Mortimer, P. E.;  Kakumyan, P.;  Hyde, K. D.;  Xu, J.
浏览  |  Adobe PDF(569Kb)  |  收藏  |  浏览/下载：238/75  |  提交时间：2019/09/10
Cancer  Cardiovascular disorders  Constipation  Diabetes  Medicinal mushrooms  Metabolic Syndrome  Polysaccharides  
Simultaneous quantification of endogenous and exogenous plasma glucose by isotope dilution LC-MS/MS with indirect MRM of the derivative tag 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2018, 卷号: 410, 期号: 7, 页码: 2011-2018
作者:  Yu, Lingling;  Wen, Chao;  Li, Xing;  Fang, Shiqi;  Yang, Lichuan;  Wang, Tony;  Hu, Kaifeng
收藏  |  浏览/下载：156/0  |  提交时间：2018/05/08
Derivatization  Diabetes  Endogenous Glucose  Exogenous Glucose  Lc-ms/ms  
Gene Expression and Correlation of Pten and Fabp4 in Liver, Muscle, and Adipose Tissues of Type 2 Diabetes Rats 期刊论文
MEDICAL SCIENCE MONITOR, 2015, 卷号: 21, 期号: 8, 页码: 3616-3621
作者:  Su,Di;  Zhang,Chuan-ling;  Gao,Ying-chun;  Liu,Xiao-ying;  Li,Cai-ping;  Jian Huangfu;  Xiao,Rui
浏览  |  Adobe PDF(265Kb)  |  收藏  |  浏览/下载：192/65  |  提交时间：2016/01/19
Fatty Acid-binding Proteins  Diabetes Mellitus  Pten Phosphohydrolase  Type 2  
Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11 beta-HSD1 inhibitors: Potential impact in diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 65, 页码: 403-414
作者:  Deng, Xu;  Shen, Yu;  Yang, Jing;  He, Juan;  Zhao, Yu;  Peng, Li-Yan;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1215Kb)  |  收藏  |  浏览/下载：451/162  |  提交时间：2013/10/16
Ent-kaurene Diterpenoids  Structure-activity Relationship Studies  Selective 11 Beta-hsd1 Inhibitors  Urea Derivatives  Diabetes