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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：160/24  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Physiological response and photosynthetic recovery to an extreme drought: Evidence from plants in a dry-hot valley savanna of Southwest China 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 868, 页码: 161711
作者:  Yang,Da;  Wang,Yang-Si-Ding;  Wang,Qin;  Ke,Yan;  Zhang,Yun-Bing;  Zhang,Shi-Bao;  Zhang,Yong-Jiang;  McDowell,Nate G.;  Zhang,Jiao-Lin
浏览  |  Adobe PDF(3590Kb)  |  收藏  |  浏览/下载：156/14  |  提交时间：2024/07/17
Extreme drought  Gas exchange  Hydraulic conductance  Photosynthesis  Physiological response  Valley savannas  LEAF HYDRAULIC CONDUCTANCE  WATER-USE EFFICIENCY  STOMATAL CLOSURE  TROPICAL SAVANNA  CLIMATE-CHANGE  SEGMENTATION  MECHANISMS  STEM  VULNERABILITY  PRODUCTIVITY  
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Lee,Julia Kin -Ming;  Puno,Pema Tenzin;  Lau,Clara Bik-San
浏览  |  Adobe PDF(16654Kb)  |  收藏  |  浏览/下载：142/17  |  提交时间：2024/07/22
Breast cancer  Metastasis  Natural products  Eriocalyxin B  Cancer recurrence  Cancer stem cells  Gut microbiome  NF-KAPPA-B  STEM-CELLS  MOLECULAR-MECHANISMS  EXTRACELLULAR-MATRIX  TUMOR-GROWTH  APOPTOSIS  ANGIOGENESIS  PROGRESSION  CARCINOMA  LEUKEMIA  
RUNX1-Regulated Signaling Pathways in Ovarian Cancer 期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
作者:  Chen,Yuanzhi;  He,Yingying;  Liu,Shubai
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Runt-related transcription factor 1 (RUNX1)  ovarian cancer  apoptosis  signaling pathways  clinical therapeutic target  GROWTH-FACTOR  TRANSCRIPTION FACTORS  STEM-CELLS  RUNX1  STAT3  FAMILY  ACTIVATION  APOPTOSIS  LEUKEMIA  SURVIVAL  
Two Novel Iboga-Type and an Oxindole Glucuronide Alkaloid from Tabernaemontana peduncularis Disclose Related Biosynthetic Pathways to Tabernaemontana divaricata 期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 18, 页码: 6664
作者:  Traxler,Florian;  Zhang,Haoqi;  Mahavorasirikul,Wiratchanee;  Krivanek,Katharina;  Cai,Xiang-Hai;  Aiyakool,Wichai;  Pfeiffer,Martin;  Brecker,Lothar;  Schinnerl,Johann
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Apocynaceae  Tabernaemontana peduncularis  Tabernaemontana divaricata  javaniside  indole alkaloid  glucuronide alkaloid  MONOTERPENE INDOLE ALKALOIDS  BISINDOLE ALKALOIDS  ALANGIUM-JAVANICUM  STEM BARK  GLYCOSIDES  OXIDATION  LOGANIN  LEAVES  GENUS  
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
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PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
seco-Prezizanne Sesquiterpenes and Prenylated C6-C3 Compounds from the Fruits of Illicium lanceolatum A. C. Smith 期刊论文
CHEMISTRY & BIODIVERSITY, 2022, 卷号: 19, 期号: 1, 页码: e202100868
作者:  Nie,Wei;  Ding,Lin-Fen;  Tie-Lei;  Zhou,Hao-Feng;  Bao,Yi;  Song,Liu-Dong;  Pan,Zheng-Hong;  Wu,Xing-De;  Zhao,Qin-Shi
浏览  |  Adobe PDF(1850Kb)  |  收藏  |  浏览/下载：325/94  |  提交时间：2022/04/02
Illicium lanceolatum A  C  Smith  seco-prezizanne sesquiterpene  prenylated C6-C3 compound  neuroprotective activity  NEUROTROPHIC ACTIVITY  C-6-C-3 COMPOUNDS  STEM BARK  ROOTS  SKELETON  
Genome-Wide Analysis of the WOX Transcription Factor Genes in Dendrobium catenatum Lindl. 期刊论文
GENES, 2022, 卷号: 13, 期号: 8, 页码: 1481
作者:  Li, Hefan;  Li, Cheng;  Wang, Yuhua;  Qin, Xiangshi;  Meng, Lihua;  Sun, Xudong
浏览  |  Adobe PDF(4464Kb)  |  收藏  |  浏览/下载：82/22  |  提交时间：2024/08/21
Dendrobium catenatum Lindl  WOX transcription factor family  phylogenetic analysis  regulation of gene expression  expression profiles  phytohormone response  STEM-CELL REGULATION  EXPRESSION ANALYSIS  ARABIDOPSIS  WUSCHEL  FAMILY  IDENTIFICATION  ROLES  SHOOT  RICE  
New Genes Interacted With Recent Whole-Genome Duplicates in the Fast Stem Growth of Bamboos 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2021, 卷号: 38, 期号: 12, 页码: 5752-5768
作者:  Jin,Guihua;  Ma,Peng-Fei;  Wu,Xiaopei;  Gu,Lianfeng;  Long,Manyuan;  Zhang,Chengjun;  Li,De-Zhu
收藏  |  浏览/下载：253/0  |  提交时间：2022/04/02
fast stem growth  orphan genes  de novo genes  WGD  woody bamboos  evolutionary innovation  EVOLUTIONARY ORIGIN  DROSOPHILA-MELANOGASTER  PHYLOGENETIC ANALYSIS  VERTEBRATE EVOLUTION  RAPID EVOLUTION  HUMAN TISSUE  YOUNG GENES  TRANSCRIPTION  EXPRESSION  HOURGLASS  
A new antimicrobial nor-friedelane-type triterpenoid and other constituents from Plectranthus glandulosus Hook. f. (Lamiaceae) 期刊论文
NATURAL PRODUCT RESEARCH, 2021
作者:  Tedonkeu,Alex Tchinda;  Tamokou,Jean-De-Dieu;  Mpetga,James D. Simo;  Nzogong,Raissa Tioyem;  Kengne,Irene Chinda;  Hao,Xiao-Jiang;  Tene,Mathieu
收藏  |  浏览/下载：185/0  |  提交时间：2022/04/02
Plectranthus glandulosus  Lamiaceae  triterpenoids  nor-friedelane  antimicrobial activity  STEM BARK  ACID  FLAVONE  EXTRACT  PLANT