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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
Authors:
Dai, Manyun
;
Peng, Wan
;
Zhang, Ting
;
Zhao, Qi
;
Ma, Xiaofang
;
Cheng, Yan
;
Wang, Chunyan
;
Li, Fei
Favorite
  |  
View/Download:156/0
  |  
Submit date:2022/07/15
Tripterygium wilfordii
Liver injury
PPAR alpha
IL6-STAT3
Metabolomics
Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
Authors:
Li,Xu-xia
;
Zhang,Peng
;
Yang,Yang
;
Wang,Jing-jing
;
Zheng,Yan-jun
;
Tan,Ji-liang
;
Liu,Shen-yan
;
Yan,Yong-ming
;
Zhang,You-yi
;
Cheng,Yong-xian
;
Yang,Huang-tian
Favorite
  |  
View/Download:11/0
  |  
Submit date:2022/04/02
cardiac hypertrophy
pyrazine derivative
QF84139
phenylephrine
transverse aortic constriction
AMPK signaling pathway
PROTEIN-KINASE
MAMMALIAN TARGET
OVERLOAD
METFORMIN
MACROPHAGES
MECHANISMS
MEDICINE
ALPHA
CELLS
MODEL
PXR mediates mifepristone-induced hepatomegaly in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:
Yao,Xin-peng
;
Jiao,Ting-ying
;
Jiang,Yi-ming
;
Fan,Shi-cheng
;
Zhao,Ying-yuan
;
Yang,Xiao
;
Gao,Yue
;
Li,Fei
;
Zhou,Yan-ying
;
Chen,Pan-pan
;
Huang,Min
;
Bi,Hui-chang
Favorite
  |  
View/Download:19/0
  |  
Submit date:2022/04/02
mifepristone
hepatomegaly
pregnane X receptor (PXR)
yes-associated protein (YAP)
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models
期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 1, 页码: 17-24
Authors:
Wang,Gan
;
Yang,Meng-Li
;
Duan,Zi-Lei
;
Liu,Feng-Liang
;
Jin,Lin
;
Long,Cheng-Bo
;
Zhang,Min
;
Tang,Xiao-Peng
;
Xu,Ling
;
Li,Ying-Chang
;
Kamau,Peter Muiruri
;
Yang,Lian
;
Liu,Hong-Qi
;
Xu,Jing-Wen
;
Chen,Jie-Kai
;
Zheng,Yong-Tang
;
Peng,Xiao-Zhong
;
Lai,Ren
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  |  
View/Download:20/0
  |  
Submit date:2022/04/02
SARS
ENTRY
MERS
High-quality evergreen azalea genome reveals tandem duplication-facilitated low-altitude adaptability and floral scent evolution
期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 期号: 12, 页码: 2544-2560
Authors:
Wang,Xiuyun
;
Gao,Yuan
;
Wu,Xiaopei
;
Wen,Xiaohui
;
Li,Danqing
;
Zhou,Hong
;
Li,Zheng
;
Liu,Bing
;
Wei,Jianfen
;
Chen,Fei
;
Chen,Feng
;
Zhang,Chengjun
;
Zhang,Liangsheng
;
Xia,Yiping
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  |  
View/Download:18/0
  |  
Submit date:2022/04/02
Azalea
Rhododendron ovatum
altitude
adaptability
floral scent
terpene synthase (TPS)
tandem duplication
defence response
PHYLOGENETIC ANALYSIS
TERPENE SYNTHASES
PLANT VOLATILES
SALICYLIC-ACID
JASMONIC ACID
WHOLE-GENOME
GENE
DIVERSITY
TOOL
TRANSCRIPTOME
Genome-Wide Analysis of the TCP Transcription Factor Genes in Dendrobium catenatum Lindl.
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 19, 页码: 10269
Authors:
Zhang,Li
;
Li,Cheng
;
Yang,Danni
;
Wang,Yuhua
;
Yang,Yongping
;
Sun,Xudong
Favorite
  |  
View/Download:19/0
  |  
Submit date:2022/04/02
Dendrobium catenatum Lindl.& nbsp
TCP transcription factor family & nbsp
phylogenetic analysis & nbsp
expression profiles & nbsp
phytohormone response
EXPRESSION ANALYSIS
JASMONIC ACID
DOMAIN
IDENTIFICATION
BIOSYNTHESIS
BRANCHED1
EVOLUTION
SEQUENCE
ELEMENTS
BINDING
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:
Zhu,Yan-Yan
;
Jin,Qiong
;
Chen,Shan-Shan
;
Jin,Dan-Ni
;
Wang,Zhao-Jie
;
He,Ying-Jie
;
Chen,Hui-Cheng
;
Zhao,Yun-Li
;
Zhao,Li-Xing
;
Dai,Zhi
;
Luo,Xiao-Dong
Favorite
  |  
View/Download:36/0
  |  
Submit date:2022/04/02
Neothalfine
Bisbenzylisoquinoline alkaloid
Metastatic colorectal cancer
Metabolomic
Mitochondrial apoptosis
SMALL MOLECULES
IRINOTECAN
RESISTANCE
CELL
IMMUNOTHERAPY
OPPORTUNITIES
CHEMOTHERAPY
VINORELBINE
ALKALOIDS
PATHWAY
HRESIMS-guided isolation of aspidosperma-scandine type bisindole alkaloids from Melodinus cochinchinensis and their anti-inflammatory and cytotoxic activities
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 184, 页码: 112673
Authors:
Li,Fang-Ru
;
Liu,Lu
;
Liu,Ya-Ping
;
Wang,Jin-Tang
;
Yang,Mei-Lian
;
Khan,Afsar
;
Qin,Xu-Jie
;
Wang,Yu-Dan
;
Cheng,Gui-Guang
Favorite
  |  
View/Download:14/0
  |  
Submit date:2022/04/02
Melodinus cochinchinensis (Lour.) Merr. (Apocynaceae)
melokhanines
Bisindole alkaloids
Anti-inflammatory
Cytotoxicity
MONOTERPENOID INDOLE ALKALOIDS
CHEMISTRY
FRUITS
New Genes Interacted With Recent Whole-Genome Duplicates in the Fast Stem Growth of Bamboos
期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2021, 卷号: 38, 期号: 12, 页码: 5752-5768
Authors:
Jin,Guihua
;
Ma,Peng-Fei
;
Wu,Xiaopei
;
Gu,Lianfeng
;
Long,Manyuan
;
Zhang,Chengjun
;
Li,De-Zhu
Favorite
  |  
View/Download:20/0
  |  
Submit date:2022/04/02
fast stem growth
orphan genes
de novo genes
WGD
woody bamboos
evolutionary innovation
EVOLUTIONARY ORIGIN
DROSOPHILA-MELANOGASTER
PHYLOGENETIC ANALYSIS
VERTEBRATE EVOLUTION
RAPID EVOLUTION
HUMAN TISSUE
YOUNG GENES
TRANSCRIPTION
EXPRESSION
HOURGLASS
Genetic innovations: Transposable element recruitment and de novo formation lead to the birth of orphan genes in the rice genome
期刊论文
JOURNAL OF SYSTEMATICS AND EVOLUTION, 2021, 卷号: 59, 期号: 2, 页码: 341-351
Authors:
Jin,Gui-Hua
;
Zhou,Yan-Li
;
Yang,Hong
;
Hu,Yan-Ting
;
Shi,Yong
;
Li,Ling
;
Siddique,Abu N.
;
Liu,Chang-Ning
;
Zhu,An-Dan
;
Zhang,Cheng-Jun
;
Li,De-Zhu
Favorite
  |  
View/Download:24/0
  |  
Submit date:2022/04/02
comparative genomics
origin
orphan gene
transposable element
LINEAGE-SPECIFIC GENES
EVOLUTION
ORIGIN
IDENTIFICATION
EMERGENCE
PROTEIN
DUPLICATION
ALIGNMENT
SETS